Alex Puissant Lab

Alex Puissant, Ph.D., is a Principal Investigator in the Hematology-Oncology Department at the Saint Louis Research Institute & Hospital, Paris, France.

[Mick Milsom @MilsomMick]

Just over 2 weeks to go

[Alex Puissant Lab @LabPuissant]

@lane_andy @Ran47800515 @BloodAdvances Outstanding technology! Congrats Andy and the Team!

[Science Translational Medicine @ScienceTM]

New #GeneEditing systems named PRINCE and Little Prince employ small molecules to control both nuclease and guide RNAs—achieving precise control over the duration of gene editing and reducing off-target edits in mouse models. @Shenzhensuat_sz https://t.co/TCVzWlnhQM

[Alex Puissant Lab @LabPuissant]

@Michelkahi Amazing study! Congrats Michel!

[Michel Kahi @Michelkahi]

Excited to share a publication from my PhD work in Nature Communications. Grateful to Dr. Frederic Bost for his mentorship and to the Ligue contre le cancer for supporting this research.

#NatureCommunications #ProstateCancer #c3m https://t.co/GTfllbcbEE

[Alex Puissant Lab @LabPuissant]

@DanaFarber That’s amazing! Congratulations Andy! @lane_andy

[Alex Puissant Lab @LabPuissant]

@jer_06200 @ChicheJohanna Congratulations to the whole Team 🎉🎉

[Alex Puissant Lab @LabPuissant]

@FagnanAlexandre @Nature Congrats Alex on this outstanding study!

[Alex Puissant Lab @LabPuissant]

@lydfinley @CellCellPress @jules_stef Congrats Lydia and the Team on this great study!

[Alex Puissant Lab @LabPuissant]

@bdcrompton @DanaFarberNews @DFBC_PedCare Congratulations Brian! Very exciting news :)

[Science Translational Medicine @ScienceTM]

The new issue of #ScienceTranslationalMedicine is out!

A marker of poor outcomes during invasive candidiasis could inform personalized therapies, a skin temperature study in patients helps answer a longstanding question in narcolepsy research, and more. https://t.co/u3oDwRFF4H

[Nature Metabolism @NatMetabolism]

Methylation, acetylation and cell fate https://t.co/g0OtJpokZu

[Science Translational Medicine @ScienceTM]

A screening study that leverages SPOKE knowledge graphing examines over 1500 known drugs, and reveals that the drug candidate #bavisant has remyelinating and neuroprotective properties in models of #MultipleSclerosis. @InstitutCerveau https://t.co/24AtPtQHEG

[Nature Metabolism @NatMetabolism]

RESEARCH | AE Stewart, DK Zachman, A Puissant, KC Wood, @matthewhirschey et al (@Inserm)

A #MachineLearning based approach probing pathway coessentiality reveals that #ComplexII of the ETC regulates de novo #purine synthesis, and can be targeted for AML

https://t.co/LT9SARYZje

[Alex Puissant Lab @LabPuissant]

@LinPierreZhao Congrats Lin-Pierre!!

[nature @Nature]

Nature research paper: Polyamine-dependent metabolic shielding regulates alternative splicing

https://t.co/SwtpzBJe8d

[Science Translational Medicine @ScienceTM]

Monitoring markers of #tau protein in the blood can predict functional outcomes in patients recovering from ischemic #stroke better than MRI, according to a comprehensive study of more than 1200 patients. @ISD_Research https://t.co/1WYuJk8eeT

[Alex Puissant Lab @LabPuissant]

@BCD_AACR Congratulations Ross!!!

[Science Translational Medicine @ScienceTM]

A team applies CT/PET imaging in #tuberculosis lung lesions in marmosets receiving 22 different treatment protocols, and shows imaging can predict known clinical outcomes from shortened and standard regimens. @AldridgeLab @taliagreenstein @TuftsMedSchool https://t.co/OLb5AZ1HsP

[Science Translational Medicine @ScienceTM]

Gene expression profiling of #dengue infections finds that peripheral blood mononuclear cells #PBMC drawn from symptomatic and symptomatic individuals have distinct immune profiles. @sangerinstitute @MahidolU https://t.co/y5eypd49Ru