The ScorranoLab

Scorrano Lab @DiBio_UniPD & @VIMMPadua. We study #mitochondria #celldeath #contactsites #metabolism #cristae #Opa1. Luca's tweets are signed LS

[Fusion Conferences @Fusion_Conf]

This is your reminder there is only ✨2 WEEKS✨to go until our final registration deadline for #FusionAging25
📜Final Few Poster Slots Remaining!
🗓️Deadline: Thursday 07 Aug 2025
🔗Register here: https://t.co/fDNHBiblPJ

[The ScorranoLab @LabScorrano]

This work identifies OPA1-targeting strategies as promising for metastatic TNBC. Big thanks to the funders @AIRC_it @Fondaz_Veronesi 6/6 LS

[The ScorranoLab @LabScorrano]

Kudos to Antigoni Diokmetzidou, @aurora_maracani, @mau_carr, @AnnaPellattiero, Erwan Rivière for their new @cddpress paper where we make good use of the Opa1 inhibitors that we generated in the lab! Check the paper out here https://t.co/IrUdkqzgQs 1/6

[The ScorranoLab @LabScorrano]

Pharmacological inhibition with our OPA1 inhibitors MYLS22 and Opitor‑0 confirms selective vulnerability: these small molecules reduce migration and induce cell death exclusively in metastatic lines. 5/6

[The ScorranoLab @LabScorrano]

I promise that the style of our presentations is a little bit more plain. LS

[Mambo Italiano @mamboitaliano__]

If you’re visiting Puglia, Italy 🇮🇹 this summer, don’t forget to stop by Scorrano

A small town in the province of Lecce, known worldwide for its stunning light displays ✨

These are true Gothic cathedrals made of lights and colors

The very essence of Southern Italy

[The ScorranoLab @LabScorrano]

This poster is a must have for labs working on #MCS! A guide through the work of so many outstanding labs (apologies if we did not cite your work). Hang it in your office or lab, it will please your eyes and inspire your mind! Kudos to the driving force Antigoni Diokmetzidou! -LS

[J Cell Science @J_Cell_Sci]

In their Cell Science at a Glance article, Antigoni Diokmetzidou & Luca Scorrano @LabScorrano summarise the mitochondrial contacts characterised in mammals, the mechanisms underlying their formation, and their principal functions.
https://t.co/zKHSh7w3Wa
#JCSMitoSI #OpenAccess

[The ScorranoLab @LabScorrano]

11/11 Special thanks to @AIRC_it that funded this project @FRBiomedica since its inception and to grants from @FondazioneHeal @fondcariparo @mur_gov_. Many improved Opitors to follow, hoping to bring them soon to the clinics for the benefit of #AML and other cancer patients! LS

[The ScorranoLab @LabScorrano]

Kudos to @AnnaPellattiero C Quirin @MagrinFederico, great collaborators S Moro A Mattarei @msturlese @ProfGavathiotis for our latest @ScienceAdvances paper https://t.co/WJdTiajt7p. Many years in the making but finally we have OPA1 inhibitors reverting cancer chemoresistance! 1/

[The ScorranoLab @LabScorrano]

10/ Stay tuned for our collaborative work with the labs of @glytsou @iannisaifantis1 where we show how effective these new Opitors are in models of #AML, where #Venetoclax resistance can be driven by OPA1 and is an important and unmet clinical need!