The Lab LaBella

The Lab LaBella at UNC-Charlotte. Codons, Complex Traits, Fungi, Humans.
All opinions my own
Run by Dr. Abigail Leavitt LaBella

[The Lab LaBella @Lab_LaBella]

Diversity is a core part of #Evol2023 at every level!

Come check out the surprising diversity we uncovered by characterizing >1,000 species of yeast!

Think all yeast are the same? Well, that would be like saying humans and worms are the same!

[The Lab LaBella @Lab_LaBella]

@ScienceIsMetal @MorganCarterPhD might know!

[Richard Allen White III, PhD @raw9371]

Well done, Jose and Andrew! It's 12 years in the making. #kmers #mercat2 #teamraw #rawlab
https://t.co/mFOtA5mA5W

[The Lab LaBella @Lab_LaBella]

While starting up my research at @unccharlotte I helped complete an incredible project capturing the genetic & phenotypic diversity of THE YEASTS!
In the LaBella Lab we will be leveraging this data to continue our research on the genetic code and fungi! https://t.co/WyfM3O17Oj

[The Lab LaBella @Lab_LaBella]

@nicolo_tellini @HittingerLab @RokasLab @DOpulente We still have a lot to learn about the specialist yeasts! Especially about how their specialization may give them an advantage in the environment. In the lab, and in their own cultures, the specialists would likely lose a head-to-head race to eat all the carbon source first.

[The Lab LaBella @Lab_LaBella]

Thank you so much for taking me on this incredible journey.

From the Scopes Trial to 1,154 genomes... it's been quite the adventure with the @RokasLab

[RokasLab @RokasLab]

A decade or two ago we could only dream of having genomes for all species of a major branch of the tree of life. Thanks to the Y1000+ Project, the dream is now reality! Kudos to @HittingerLab @DOpulente @Lab_LaBella @MarizethGroene1 & the whole TEAM https://t.co/LdjEQy2BXH

[Engford Education Consultant @engfordedu]

Genomic factors shape carbon and nitrogen metabolic niche breadth across Saccharomycotina yeasts | Science https://t.co/POceo796uo

[Steve Marek @stephenmarek2]

Genomic factors shape carbon and nitrogen metabolic niche breadth across Saccharomycotina yeasts | Science https://t.co/2loXOTvLEC

[The Lab LaBella @Lab_LaBella]

I want to add an enormous THANK YOU to my co-author Dana @DOpulente (right) and our fearless leaders @RokasLab @HittingerLab (whose nametags we stole)

We have done so much amazing work since the 2018 GRC

I cannot wait to see what we do next!

[HittingerLab @HittingerLab]

The big Y1000+ Project manuscript is finally published in Science magazine! Years of work with @RokasLab, @DOpulente, @Lab_LaBella, Marizeth Groenewald, the late Clete Kurtzman, and many others:
https://t.co/8sxXRv6u8A

[Molecular Biology and Evolution @MolBioEvol]

Don't miss the original article from @HittingerLab @RokasLab @LiangSu45216672 @KyleTheDavid @ciggoncalves @DOpulente @Lab_LaBella @MarizethGroene1 @shenxingxing1 https://t.co/47uZxVFSlj

[Molecular Biology and Evolution @MolBioEvol]

@HittingerLab @RokasLab @LiangSu45216672 @KyleTheDavid @ciggoncalves @DOpulente @Lab_LaBella @MarizethGroene1 @shenxingxing1 And check out this lovely cover image of plates spotted with yeast and overlaid with a blue dye that changes color when iron is removed by Drew T. Doering.

[The Lab LaBella @Lab_LaBella]

Popping in to point #fungal24 towards my other account over on 🟦sky -> lablabella

[The Lab LaBella @Lab_LaBella]

Check out what one of the LaBella Lab Master's interns got up to this summer.

Evolutionary medicine is so fun!

@unccharlotte @UNCC_BIGScience

https://t.co/PPnJv2KS7L

[Rfam @RfamDB]

Happy International RNA day! The RNA codon that initiates protein synthesis in cells written as AUG so we celebrate RNA day today - 1st AUGust #RNAday #AUG

[The Lab LaBella @Lab_LaBella]

It's small
It's mighty
It's the POWERHOUSE OF THE CELL!
It's the MITOCHONDRIA!

Preprint from J Wolters, @HittingerLab @RokasLab @Lab_LaBella @DOpulente

https://t.co/SAQMVGdXaH

[yoheLab @LabYohe]

So thrilled to share our new #OpenAccess perspectives article in a special @AnatomyOrg issue honoring anatomist Kunwar Bhatnagar. Genomics asks questions only anatomy can answer... First Yohe Lab pub with a @UNCC_BIGScience student too! 🦇👃🧬🩻 https://t.co/Y8fGVtrMGY

[Dan Sloan @SloanEvoLab]

We also have follow-up project plans to test specificity between aminoacyl-tRNA synthetases and their tRNA substrates in this system and in parasitic plants. If you have experience with aminoacylation assays and are looking for a job and a cool project, get in touch!

[The Lab LaBella @Lab_LaBella]

YEAST PREPRINT!
@MarieClaireHar2 leverages machine learning to reveal who, how and why galactose metabolism evolved in yeasts

Surprise! Not all yeast use the GAL genes

@Lab_LaBella @DOpulente @shenxingxing1 @MarizethGroene1 @HittingerLab @RokasLab

https://t.co/mtzsIsxVwR

[Richard Allen White III, PhD @raw9371]

Check our integrate method for counting viruses in aquatic ecosystems and modern microbialites. Roughly all the viruses in Great Salt Lake weigh about as much as a standard red brick (if you assume T7 size of 50 million daltons).
https://t.co/xu7LhjB0HU

[Genetics Society of America @GeneticsGSA]

The July GENETICS cover image of a double-helix drill bit forged in 1820 by enslaved blacksmith Solomon Williams accompanies a study from J.A. Mooney et al. on the genetic and genealogical history of African Americans from the 17th century to the 1960s. https://t.co/MPoqscT6kP