Our work on NRTIs and Alzheimer's disease was highlighted today in the Wall Street Journal op-ed "You Can Teach an Old Drug New Tricks," and in the policy report it links to from the University of Chicago & Duke Margolis Institute on pull funding for generic drug repurposing.
https://t.co/M6FoAdInvS
Across 270,000+ patients in two major health databases, NRTIs are HIV drugs that also block inflammasomes and cut Alzheimer's risk by 6-13% per year of treatment, potentially preventing ~1 million new cases annually (Alzheimer's & Dementia). The same inflammasome biology drives diabetes too, where NRTIs reduce risk by 33% (Nature Communications).
The next chapter: K8 and K9, our next-gen inflammasome inhibitors (Kamuvudines), are the direct descendants of this work, safer, more potent, and already in clinical trials.
UChicago/Duke Margolis pull funding report:
https://t.co/plY1F4ZyQa
UVA Health on NRTIs & Alzheimer's disease:
https://t.co/rIWx1gmLPy
UVA Health on NRTIs & diabetes:
https://t.co/mcvAxSE7Bd
At Inflammasome Therapeutics, we’re developing new therapies for retinal and neurodegenerative diseases!
In the latest episode of Retina Synthesis, Dr. Jayakrishna Ambati, Founder of Inflammasome Therapeutics, discusses Phase 2 clinical trial results for Kamuvudine-8 (K8), a novel inflammasome inhibitor, in Geographic Atrophy.
https://t.co/MvBzMMEVLw
Congratulations to @OPHSWBB Osbourn Park High School Women’s Basketball in @PWCSNews for winning the 2026 State Championship, successfully defending their 2025 title! BACK TO BACK!
Well said Secretary Frazier! 💪@AgForestryVA. Gov. Spanberger shouldn’t allow tens of thousands of predatory “skill” slot machines on every Virginia street corner. Make Virginia’s gaming fairer & safer first @GovernorVA@VaAgComm@ltgovhashmi@jonesjay
Alexandria Councilman Canek Aguirre asking state lawmakers to oppose a bill legalizing “skill” slot machines, citing the harmful impacts on local business owners.
Bravo @CanekForCouncil Well done.
Link to story in @AlexandriaNow https://t.co/edIfut8LNq
“Skill” slot machines have operated for years in violation of state law.
Legalizing slot machines in every corner store REWARDS bad actors & sets a terrible precedent for how to do business in Virginia.
…and @GovernorVA said the focus was on affordability & cost of living.
"Have we no sense of decency?"
Virginia does NOT need "iGaming”-casino gambling on cell phones 24/7/365 days a year. Cell phone roulette has terrible outcomes: Addiction among kids & adults skyrocket. Bankruptcies spike.
VOTE NO on HB161-gambling 24/7 at home/work/school.
Inbox: A former Director of National Compliance for skill game developer Pace-O-Matic has pled guilty to money laundering for funneling "hundreds of thousands of dollars in payments from non-compliant distributors and operators" through an LLC instead of reporting the issue.
The first question in every interview:
“So, tell me a bit about yourself?”
Don’t talk about your hobbies.
Don’t repeat your resume.
Say this instead 👇
A Harvard student told me something I can't stop thinking about. When they go to the library, every single screen has ChatGPT open. Homework that used to take hours now takes minutes.
But then they talk to alums who say entry-level roles are basically gone. The jobs they planned their entire college trajectory around don't exist anymore.
AI made homework easier but made proving you deserve a job exponentially harder.
Congratulations to @jonesjay on becoming our next Attorney General. The work of this office is absolutely critical to the Commonwealth, especially now, as all of our institutions are under attack by a reckless and irresponsible administration in DC. Time to get to work!
Virginia state Sen. Ghazala Hashmi on Tuesday became the first Muslim-American woman elected to statewide office in the U.S. with her victory in the state's lieutenant governor's race, NBC News projects.
https://t.co/F3ecWeetgs
Outstanding work by my dear friend @LilyForDelegate
She ran a campaign focused on the issues affecting Virginians on a daily basis and she will work every single day for her constituents!