The Mulder & Simon Labs are looking for a talented Postdoctoral Fellow to join our team to study HERVs! Are you or someone you know interested in this exciting opportunity? Check out the link below! #hiring#teamscience#virology
https://t.co/nQwYId4bqF
Two beautiful new papers show mechanisms by which #SARSCoV2 omicron evolved to antagonize innate immunity - paralleling evolution of innate immune antagonism in pre-omicron variants. Link to my spotlight, available OA through Feb 12 @TrendsImmuno: https://t.co/dqan2unytG
Impacts of SARS-CoV-2 ORF6. @LisaMiorin & Co show ORF6 is innate immune antagonist that binds Nup98-Rae1 & suppresses host gene expression by selectively inhibiting nucleocytoplasmic trafficking. ORF6 loss-of-function mutations cause #SARSCoV2 attenuation https://t.co/OkRmtkZ9h2
Officially out in @CellCellPress: Systematic comparison of SARS-CoV-2 variants of concern (Alpha, Beta, Gamma, Delta, & Omicron) using global proteomic and genomic analyses during infection to understand the molecular responses driving viral evolution ๐งต๐ https://t.co/TXvwbN0MsK
To learn more about how different SARS-CoV-2 variants escape from human immune system barriers to increase transmissibility and infectivity check out also our accompanying manuscript led by @KroganLab and @DoctorBou published today in @CellCellPress https://t.co/viGanKyffv
I'm so excited that our latest work addressing the role of SARS-CoV-2 ORF6 and its variant polymorphisms on host responses and viral pathogenesis is officially out today in @cellhostmicrobe !!!
https://t.co/DRdq3dxbQZ