Long Hu

[Gong Chen @GongChenLab]

We’ve been dreaming of this type of conjugation chemistry for years—and finally, a simple fix to a stubborn problem, all thanks to just a tiny drop of CS₂. Minimalist chemistry is the new gold. ✨

[Long Hu @LongHu1992]

@adak_tps Congratulations！👍

[Teck-Peng LOH Research Group @lab_TPLoh]

We present an amine-differentiating amide synthesis using an sp-carbon-activated ester. The bulky TIPS group prevents unwanted reactions while allowing for easy removal, facilitating post-modifications like click reactions and peptide-drug conjugations.
https://t.co/oJAAklMxEE

[Hansmann Lab @MMHansmann_chem]

Finally it’s official: Our manuscript on a new reagent for C-atom transfer is out @ScienceMagazine! Diazo transfer from N2O gives access to Ph3PCN2 a versatile reagent. Big congratulations to the team! @TU_Dortmund @ERC_Research @AvHStiftung @phosphorchem https://t.co/kCyZfh6znq

[Mind @MindCharity]

It’s Men’s Health Week, remember this 🩵

Men,

It’s okay to cry.
It’s okay to show emotion.
It’s okay to be emotional.
It’s okay to feel sad.
It’s okay to be okay.
It’s okay to not be okay.
It’s okay to feel.
It’s okay to grieve.
It’s okay to tell someone you’re struggling.
It’s okay to talk.
It’s okay to struggle.
It’s okay to fail.
It’s okay to feel lost.

It’s okay to talk about your mental health.

[Manfred Bochmann @BochmannGroup]

Gold-Catalysed Heck Reaction: Fact or Fiction?
Preprint out now: https://t.co/FNRUQcABIF
No evidence for literature claims of gold catalyzed alkene insertion, β-H elimination or chain walking!

[Long Hu @LongHu1992]

Very excited to see the cover art of our new publication in Accounts of Chemical Research @ACS4Authors #MyACSCover

Read the paper here: https://t.co/TDauS654zS Ynamide Coupling Reagents: Origin and Advances

[Xuechen Li @LiXuechen_HKU]

Ready to register now. 18th Chinese International Peptide Symposium at Hong Kong!

[Angewandte Chemie @angew_chem]

Peptide Stapling by Crosslinking Two Amines with alpha-Ketoaldehydes through Diverse Modified Glyoxal-Lysine Dimer Linkers (Gong Chen and co-workers) @NKU1919 https://t.co/rTEzAWEw9F

[Gong Chen @GongChenLab]

HFIP's magic shines again, enabling peptide stapling with alpha-ketoaldehydes through unique imidazolium linkers, outperforming natural “glycation” processes. We proposed HFIP aggregates act as a proton shuttle for efficient deacylative C--C cleavage.

[Long Hu @LongHu1992]

Want to learn more about ynamide coupling reagents. Please have a look.
Ynamide Coupling Reagents: Origin and Advances | Accounts of Chemical Research https://t.co/TDauS654zS

[Top Science @isciverse]

Inverse Peptide Synthesis Using Transient Protected Amino Acids

@J_A_C_S #Chemistry #Science

https://t.co/qY7P9RJwhJ

[Fernando Albericio @FAlbericio]

Our annual review of the New FDA Approval Drugs was published the last week as a pre-print,
It shows the strength of the Pharmaceutical Industry

[AusPeptide @AusPeptide]

It's time to green up chemistry 🧪 💚!

Junfeng Zhao's work on unprotected amino acids is a step in the right direction!

#AusPeptides2023

[K. Ishihara Lab. 石原研 @PIodide]

Highly Enantioselective Radical Cation [2 + 2] and [4 + 2] Cycloadditions by Chiral Iron(III) Photoredox Catalysis
S. Ohmura, K. Katagiri, H. Kato, T. Horibe, S. Miyakawa, J. Hasegawa, and K. Ishihara*
J. Am. Chem. Soc. 2023, asap.
https://t.co/994kXdFRPF

[Xuechen Li @LiXuechen_HKU]

The 18th Chinese International Peptide Symposium/14th International Peptide Symposium will be held in Hong Kong in July of 2024. Please mark your calendar, you are very welcomed to Hong Kong. We will show our warmest hospitality! Welcome!

[Fachschaft Bio-/Chemie Heidelberg @fs_chemiehd]

Am Dienstag, den 27. Juni 2023 um 17:15 Uhr hält Prof. Holger Braunschweig @LabBraunschweig die 7. Margot-Becke-Vorlesung mit Titel "Aktivierung von N₂ und anderen inerten Molekülen – Können Borylene nützlicher sein als Übergangsmetalle?" im HSW, INF 252. Schauen Sie vorbei!

[ChemistryViews @ChemistryViews]

New Synthesis Method for 2,2′-Biphenyl Gold(III) Complexes:
Tin-free procedure using dibenzosilol
https://t.co/bg5lF85cRX

[Boron-Chem-Research @Boron_Chemistry]

Atom-economic and stereoselective catalytic synthesis of fully substituted enol esters/carbonates of amides in acyclic systems enabled by boron Lewis acid catalysis (@ChemicalScience): https://t.co/cxWm1v9FiC (G. Wang | M. Oestreich @Silicon_Martin | J.-J. Feng).

[History of Chemistry @HistoryChem]

In 1955, John Sheehan🇺🇲 first reported the use of dicyclohexylcarbodiimide (DCC) as a coupling reagent for the synthesis of peptides.
#chemtwitter
Sheehan achieved the synthesis of penicillin V in 1957, one of the most challenging chemistry problems at that time.