Michael Boffa

Gone

[Michael Boffa @MBBoffa]

1/21 To mark #LpaAwarenessDay, a 🧵 on the origins of the famous Lp(a) schematic. @MarlysLPA @Lpa_Doc @Drlipid @ArsenaultBenoit @lipiddoc @grsoffer @rauldsf_santos @ProfKausikRay @jsdron @TheFHFoundation @DrZeZheng @dmljmd @calvinyeang @virani_md @CBallantyneMD @stncsn

[Michael Boffa @MBBoffa]

@MarlysLPA and I are proud to present our "Clinical Outlook" on Lp(a)-lowering therapies. Exciting times!
https://t.co/WB2KHWPwBD

[Michael Boffa @MBBoffa]

@MarlysLPA and are proud to present a "Clinical Outlook" on Lp(a)-lowering therapies. Exciting times! https://t.co/WB2KHWPwBD

[Michael Boffa @MBBoffa]

@logww45 @Drlipid The parent will only pass on one of their two LPA genes to the child, and it could be the high one or it could be the low one.

[Michael Boffa @MBBoffa]

@logww45 @Drlipid No way to tell except to measure Lp(a) in the child.

[Michael Boffa @MBBoffa]

@logww45 @Drlipid Let's say you have high Lp(a) levels...remember you have two LPA genes contributing, one from your mother and one from your father. But, one normally doesn't know if that is because you have two genes giving you high Lp(a), or one gene that contributes a lot and the other a bit.

[Precision Health Reports 📑❤️ @PreciseHlthRpt]

One key fact that everyone should know about Lp(a):

Comprehensive cardiometabolic screening and management using just lipids and basic biometrics is incomplete without also considering a one-time Lp(a) value for the individual.

Lp(a) + lipoproteins + IR + glycemic status + noninvasive imaging results + inflammation + biometrics + clinical history

[National Lipid Association @nationallipid]

Let's discuss Lp(a). Jump in and be part of this vital conversation. #CholesterolMonth

Questions are in the thread.👇

#Lpa #Lipidology #TwitterChat #Thread

[Nutrition Science @NutrioSci]

Core metabolic pathways

Source & PDF Download
Bibel, B., & The bumbling biochemist. (2024). Core Metabolic Roadmap. Zenodo.

https://t.co/oHN8AuZjVU

[Atherosclerosis @ATHjournal]

This study contributes to understanding the effects of PCSK9 inhibitor administration on plaque composition
🔗https://t.co/KRmo5aKX5D
#Evolocumab #PCS9i #CvPrev @society_eas @ELS_Cardiology

[Dr. Jonathan N. Stea @jonathanstea]

Social media is that special place where you can find someone trying to explain The Handmaid’s Tale to the author of The Handmaid’s Tale.

[Hilly Paige Jr @hillypaige2]

#KnowLpa
Superb presentation by @MarlysLPA on Lp(a) at the @cvi_phila event!
➡️ 6x more atherogenic than LDL
➡️ 20% of the population has high Lp(a); 30% of people of African descent
➡️ Pro-thrombotic
➡️ New therapies coming from @Novartis, @Amgen, @EliLillyandCo

@FamilyHeartFdn

[Hilly Paige Jr @hillypaige2]

Dr Dean Karalis and @dan_soffer kicking off the @cvi_phila program on Lp(a) with @MarlysLPA!
Excited to represent @FamilyHeartFdn at this important program!
Leading cause of death in Philly? Heart disease!

[Maya S Safarova, MD, PhD @DrSafarova]

#BeautifulCover

[Thomas Dayspring @Drlipid]

The more we learn about Lp(a) the more we have to worry about the 1 out of 5 people who have elevations. Will significantly lowering Lp(a) solve the aortic valve deterioration? For those of you with elevated Lp(a) make sure your clinicians are closely watching the heart valves. Periodic echos for all? https://t.co/JMicgPHu5O @nationallipid @society_eas @FamilyHeartFdn @escardio #KnowLpa

[Michael Boffa @MBBoffa]

Our latest review article on Lp(a), which actually made the cover of Biochemical Journal! As before this journal, we go into some depth on the more basic molecular details of Lp(a). Enjoy!

@MarlysLPA

https://t.co/a7WxMRnvUZ

[Michael Boffa @MBBoffa]

@DevikaJayaward2 presenting her fascinating work in the response of EC to Lp(a) at #CLVS2024

[Michael Boffa @MBBoffa]

Simon Ofiara makes his conference debut at #CLVS2024. Very intriguing work in Lp(a) biosynthesis!

[Michael Boffa @MBBoffa]

#CLVS first evening started with a bang, with a tour-de-force presentation by @JuliaStJohn253 on her very exciting Lp(a) transgenic mouse work!

[Michael Boffa @MBBoffa]

@robdaubs @LondonKnights 12 is what I heard.