Our new study is out! 🎉🚀
Annulate lamellae aren’t just static reservoirs, they dynamically supply pre-assembled nuclear pores to the nucleus (~1/3 of new NPCs) in normal somatic cells. A new pathway for nuclear pore assembly supporting nuclear expansion. https://t.co/eZiFKOeeHm
BREAKING NEWS
The 2025 #NobelPrize in Physiology or Medicine has been awarded to Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi “for their discoveries concerning peripheral immune tolerance.”
We’re happy to share our new study out today @NatureCellBio
We show that a chromatin factor, ZNF280A, is required for DNA double strand break repair, linking its absence to clinical features in 22q11.2 distal deletion syndrome.
@MostoslavskyLab
https://t.co/o4mEWhSLBT
Stop the doom scrolling! A new 🗞️ from my lab, describing one of our flagship projects of many years we are super excited to share:
"Inducible formation of fusion transcripts upregulates haploinsufficient CHD2 gene expression".
A 🧵https://t.co/935AvtPL8S
Thrilled to share our latest research! Our manuscript on CHD1L’s role in neurodevelopment and its implications in 1q21.1 syndromes is now on BioRxiv! 🧬🐟🧠
🔬 Read our findings here: https://t.co/zMfGWMZ9zy
#Neurodevelopment#1q21#Zebrafish#hiPSC#Autism@IGBMC
Extremely happy to share that a part of my PhD project just got published in Cell Death and Disease @cddpress https://t.co/uFlVDJIFfm
In this work, we uncover how prostate tumor microenvironment drives tumor cell plasticity.
When in evolutionary time does accelerated genomic change occur across phenotypes? Newly published today in @CellGenomics , my latest manuscript with @mashaals and @vagheesh integrates comparative, functional, and ancient genomic data with GWAS. Read more: https://t.co/0ZrcLbfEob
Excited to share our manuscript “The trait-specific timing of accelerated genomic change in the human lineage” now out in Cell Genomics https://t.co/U6UIHaKy5w with @EucharistKun and @vagheesh 1/n
Thrilled to share I’ve been awarded an @EMBO New Venture Fellowship to join @tatjana_kleele lab at @ETH_en Zürich! I’ll learn super-resolution microscopy to uncover at a single-organelle-level how mitochondrial division and function are coordinated with cell cycle progression!
Career achievement unlocked - two publications come out on the same day!
Great collaboration with Tom Sexton
https://t.co/dQnK0IkHIs
And fantastic work by Tiegh Taylor and Mitchell lab colleagues
https://t.co/0spH4Qp7J5
We are excited to share our latest work on the cooperation between RNA polymerase and the ribosome in bacteria: https://t.co/Ni4nJGJAug
The work was supported by @IGBMC, @Inserm, @CNRS, @unistra, @ERC_research, @IMC_Bio, and @instructhub. 1/7
A 1,000,000th reminder the crucial importance of basic research. Ambros and Ruvkun were looking into understanding nematode genetics and development, not looking for a drug, and ended up opening an entire new area in biology
Check our last paper in Cell Report on the transcription initiation by RNA polymerase II in TAF7 or TAF10-depleted mouse embryonic stem cells! Pol II still transcribes... This is the work of a talented former PhD candidate @HislerVincent !
https://t.co/Gnf4OS6Mam
The @CellReports issue is now out, and our work is featured on the cover! 🎨
Excited to share this illustration I created to highlight our discoveries about the conformational changes of the Cohesin domains. 🍒🐝🧬
https://t.co/4Fy00ZqtyL
#JournalCover#Cohesin#SciArt#IGBMC
If you are curious to link those illustrations to scientific discoveries, find out more here: https://t.co/4Fy00ZqtyL
A great work led by Dr. Christophe Romier's team at @IGBMC !
https://t.co/snGZSEIy0W
Delighted to share this work from a wonderful collaboration with Dr. Christophe Romier's team from @IGBMC now online on Cell Reports !
We used Zebrafish to evaluate the functional importance of the Cohesin domains and their truncated forms for proper vertebrate development 🐟
The cohesin ATPase cycle is mediated by specific conformational dynamics and interface plasticity of SMC1A and SMC3 ATPase domains https://t.co/jIm4Z9xr1c