Mancias Lab

#PancreaticCancer Research Lab interested in selective #autophagy, iron, therapeutic resistance, and #proteomics. @DanaFarber, @BrighamWomens, @harvardmed

[Mancias Lab @ManciasLab]

The Mancias Lab @DanaFarber is fighting #PancreaticCancer on #WorldPancreaticCancerDay #WPCD2017 #WPCD #PANCaware #DemandBetter @PanCAN

[SantanaCodina lab @SantanaCodina]

Excited to share our latest story @NatureComms. Here, we used quantitative proteomics, metabolomics and in vitro/in vivo CRISPR screens to define mechanisms of resistance to DHODHi in PDAC and propose combinatorial approaches with BCL-XL inhibitors:

https://t.co/I5iqDhiSGc

[Mancias Lab @ManciasLab]

@Aiims1742 @nyulangone @Perlmutter_CC Congratulations!!

[Ivan Đikić @iDikic2]

How #autophagy influences the regulation of MHC-I class receptors and regulates #immune evasion of #cancer?
A new role for an autophagy receptor IRGQ in this process with a clinical relevance for the development of liver carcinoma in humans and mice 😊😀

https://t.co/iH8YXDz0X9

[AACR @AACR]

During the keynote addresses at #AACRpan24, Eileen M. O’Reilly and Joseph D. Mancias discussed how understanding pancreatic cancer’s strengths can help researchers uncover its weaknesses. Learn more on the #AACRBlog: https://t.co/JtuLTYJxAU @EileenMOReilly @ManciasLab

[AACR @AACR]

Joseph D. Mancias discussed "Targeting Autophagy in Pancreatic Cancer" in a Rising Star Keynote Lecture during the AACR Special Conference on Advances in Pancreatic Cancer Research.
#AACRpan24 @ManciasLab

[Anirban Maitra @Aiims1742]

The (almost) full program is now online with an amazing lineup of speakers!
#AACRPan24
@EileenMOReilly @ManciasLab @DrJashDatta @TeresaZimmers @DrHendifar @JanowitzTobias @wantong_yao @MaraShermanLab @KenOliveLab @andrewaguirremd @cjder23 @bryant_kl @pratt_ed @mggoggins @ChristieTowers @Cosimo_Commisso @Chiolaboratory @nada_kalaany and those not on Twitter. See you all in Boston!
https://t.co/RWpezhGtrt
@AACR #PancreaticCancer

[Rushika M. Perera @rushika_perera]

#AACRpan23 @graceah9 presenting her poster today - an awesome collaboration with @ManciasLab

[SantanaCodina lab @SantanaCodina]

WE ARE HIRING! We are looking for a motivated postdoc to work on a fully-funded project studying the role of iron metabolism in drug resistance in pancreatic cancer. 3 weeks left to apply. Please spread the word.
https://t.co/I4WInQ5Oei

https://t.co/2WjWf3aqLV

[Mancias Lab @ManciasLab]

@MuenchLab @Nature Awesome work, Christian and team!

[Mancias Lab @ManciasLab]

@SantanaCodina @cancer_dk Congrats Naiara!

[Mancias Lab @ManciasLab]

@JEncarnacion_ Congrats Joel! Great work!

[Anirban Maitra @Aiims1742]

Our #OpenAccess review on #PancreaticCancer - advances & challenges is now online at @CellCellPress
Many thanks to @CJHPhD @Pasca_Lab & @LyssiotisLab for all the hard work & @jiaying_tan6 for the opportunity.
It’s FREE to read so share widely!
https://t.co/9R8RHGb62X

[Laurie Glimcher MD @LGlimcherMD]

We are so inspired by patients like Candace and her experience. With a loving and supportive family and the latest treatments at @DanaFarber, Candace is a source of hope for more patients with pancreatic cancer. https://t.co/oXE7vWqNZi

[Laurie Glimcher MD @LGlimcherMD]

Researchers at @DanaFarber and other institutions recently made important discoveries into the recycling system of pancreatic cancer cells, a promising step toward targeted therapies for one of the most challenging cancers. https://t.co/5B9YXMaHTy

[Dana-Farber @DanaFarber]

Pancreatic cancer cells operate a recycling program that would be the envy of any municipality — but the only beneficiaries are the cells themselves. https://t.co/gZ0FOHF0tu

[Damon Runyon Cancer Research Foundation @DamonRunyon]

A cross-country collaboration between former Damon Runyon-Rachleff Innovators @rushika_perera and @ManciasLab uncovered another way that #PancreaticCancer evades targeted therapies – and a new potential therapeutic target: https://t.co/mh5HOHfUwk

[Jonathan A. Nowak @jonathan_nowak]

Latest Wolpin-Nowak lab paper on single cell, in situ protein-based characterization of transcriptional subtypes in pancreatic cancer now out in @CR_AACR https://t.co/8IagesbQDg

[Elizabeth McKenna @ElizSMcKenna]

Now online in @CD_AACR: Targeting UGCG Overcomes Resistance to Lysosomal #Autophagy Inhibition by Vaibhav Jain, David Speicher, @AmaravadiRavi and colleagues @TheWistar @PennCancer https://t.co/VXU3pS6Owt

[Hale Family Center For Pancreatic Cancer Research @DanaFarber_Hale]

Robert Hale's determination in @DanaFarber and the Hale Family's incredible generosity help drive @DanaFarber_Hale closer to a cure for pancreatic cancer.

https://t.co/TIJwIueRus

[Mancias Lab @ManciasLab]

@mouwlab @theNCI @BrighamRadOnc @DanaFarber Congratulations!!!