New cover @NatImmunol depicting NK cell-intrinsic sex differences.
O'Sullivan & Maureen Su Labs @UCLA show that an extra copy of the X-linked epigenetic regulator UTX in female mice increases NK cell effector function in female mice. #sciart#scicomm
Thanks to @nicolekarlis for her interesting article on the front page of @Salon about our study with OSullivan Lab! @MandyICheng https://t.co/eFris4JWOi
Excited about the release of our recent paper in @NatImmunol by graduate student @MandyICheng and collaborators in @OSullivanLab about sex differences in NK cells! https://t.co/3bKyqMR0mj
UTX escapes X inactivation, regulates chromatin accessibility, & govern sex differences in NK cells. NK cell-intrinsic UTX-/- in female mice increased NK cell numbers but reduced function & compromised CMV immunity @MandyICheng@Maureen_Su_Lab O'Sullivan
https://t.co/fsB5EZmyP6
Joey Li (@thejoeyli) presented his work on NK cells at the @SNI_NKMeeting in Bonita Springs, FL. Joey is in the @OSullivanLab in the @UCLAMBI. Great job!! #NK2022
I wrote this article criticizing the obsession with individual genius (and competitions to find it) in academia. I believe we need profound reforms. Not just because our system is unjust, but also because we could achieve so much more. 🧵 1/11
https://t.co/mRzAdopVA4
Huge thanks to organizers @LabFehniger @MACattackLab for an incredible meeting! This was my first NK meeting and I’m mind blown by the science shared this weekend. It was unreal meeting giants in the field that I’ve only been reading their work for the past 4 years!! 🤯 #NK2022
🔥For today's #JournalClub 🤓
@Ashleykr16@SinaiImmunol will present a #preprint by @Maureen_Su_Lab @OSullivanLab showing that NK cell functions are sexually dysmorphic and controlled by the epigenetic regulator UTX.🎮⚡️♀️♂️
https://t.co/5hy8RcCDYG
And exciting unpublished data by Mandy which suggests that sex differences in immunology directly impact nk cell functionality. Very curious to see where this leads! 2/2