Super proud of our team for their hard work on this project. Would not have been possible without huge collaborative effort between @UCLAMBI@BC_UCLA@dgsomucla and support from @NIH
Super proud of our undergrads Christy and Michelle for their strong work at LJIC @ljiresearch@salkinstitute@immunologyUCSD . The labs they join for their PhDs will be very lucky to have them!!
Very grateful to my mentor for offering the opportunity to solo this commentary on our recent study. Here we discuss CRISPR tools for studying IEI and expand on observations linking neurodevelopment and IEI that didn’t make it in the original discussion: https://t.co/eKaewq3uAy
A long sought after hypothesis has been that organizing biomolecules in and around nuclear bodies is essential for functional RNA processing. We now provide direct evidence of this in @Nature for nuclear speckles and mRNA splicing. Check out this thread!
https://t.co/DoXSB7SINt
Fantastic work by the very talented Adalia Zhou on this month’s @NatImmunol cover art featuring our latest work. Sad to see her graduating this quarter as she moves on to Gu lab @harvardmed !
Hepatocyte activation via IL-6/STAT3 and secretion of SAA1/2 regulate T cell surveillance of extrahepatic tumors @LabBeatty@NatImmunol
https://t.co/Q6qOAvlqWk
So cool for our study to be featured by @PamelaWongPhD and @LabFehniger in @NatImmunol news & views. They thoughtfully highlight key lines of further study and unanswered questions raised by our work. Thanks Todd!
https://t.co/1Jd40KtdAq
CAR-T cells engineered to secrete cytokine modulators can reduce CRS-related toxicity while simultaneously improving in vivo antitumor efficacy @JExpMed
https://t.co/G4hKOfiycy
Out in @Nature concurrent with #AACR24
Two papers on biochemistry and preclinical characterization of Revolution Medicines’ RAS(ON) multiRAS inhibitor, with a focus on #PancreaticCancer@KenOliveLab@BenStanger01@derlabunc
https://t.co/Ptzrxtj39x
https://t.co/k5Q2buC8h0
MEF2C is a critical orchestrator of NK cell antiviral immunity by regulating SREBP-mediated lipid metabolism @NatImmunol@thejoeyli
@osullivanlab
https://t.co/GH9tpfD8Q6