Maquat Lab

Official account for Dr. Lynne Maquat's Lab at UR. Nonsense-mediated mRNA decay. Translational control. Transcriptional regulation. We love everything RNA!

[URochester SMD @URochester_SMD]

We’re thrilled to partner w/ @ualbany to form a NYS Center of Excellence in RNA research! Co-led by @MaquatLab @wagnerlab_rna, we'll team up to develop RNA-based therapies & train scientists. Huge thx to @HarryBBronson for his support #URochesterReesarch https://t.co/IiSbEK9vaR

[Maquat Lab @MaquatLab]

Congrats, Elizabeth!

[URochester SMD @URochester_SMD]

Congratulations goes out to @Dr_EAbshire, a postdoc in the @MaquatLab, who was recently awarded a K99/R00 for her project titled "Regulation of exon junction complex composition and assembly."

#URochesterResearch (1/4)

[The Nobel Prize @NobelPrize]

Katalin Karikó and Drew Weissman – awarded the 2023 #NobelPrize in Physiology or Medicine – discovered that base-modified mRNA can be used to block activation of inflammatory reactions and increase protein production when mRNA is delivered to cells.

[URochester SMD @URochester_SMD]

Cheers to RNA biologist Lynne Maquat for officially receiving the Gruber Genetics Prize @Genetics2023 in Australia for her work on nonsense-mediated mRNA decay. Proud to have you represent @UofR on an international stage! #URochesterResearch @MaquatLab https://t.co/MXntXPTpYw

[URochester SMD @URochester_SMD]

Study in @Nature details a new algorithm to find the most stable, efficient mRNA sequence to use in vaccines. Dave Mathews + @lhuang3 show optimal mRNA sequences lead to ⬆️ protein production, improved immune response @UofR @OregonState #URochesterResearch https://t.co/Mc3FnY1WCj

[URochester SMD @URochester_SMD]

New #URochesterResearch in @ScienceMagazine upends the idea that #CRISPR mounts its defense only by cutting RNA/DNA. It found a Cas protein works w/ a membrane protein 👇to stop infection in bacteria. What?? @mitchellrayoco1 @arica_vanderwal @kellogg_liz   https://t.co/cudOvRWIkq

[The RNA Institute @TheRNAInstitute]

That’s a wrap of #2023RNASymposium!
An event for the books showcasing a long standing collaboration between these amazing RNA scientists from @TheRNAInstitute & Univ of Rochester Medical Center
@BerglundLab @Wagnerlab_RNA @belfort_lab @MaquatLab @begley_lab Dave Mathews

[Maquat Lab @MaquatLab]

@XRambout_PhD, Research Assistant Professor in the
@MaquatLab, will talk about his recent research on PGC-1α and cap-binding proteins at the University of Otago, Department of Pathology, this Friday (NZ time). Seminar on Zoom. @Pathology_DSM #RNA

[Maquat Lab @MaquatLab]

@XRambout_PhD, Research Assistant Professor in the @MaquatLab, will talk about his recent work on PGC-1α and cap-binding proteins at the Young Investigator Symposium on RNA Biology this Friday.

[Xin Li @rtothepower4]

Our upcoming Young Investigator Symposium on RNA Biology this Friday and Saturday has an impressive list of 24 speakers who are postdoc and research faculty. Zoom Webinar link is only available after registration. For schedule, please visit: https://t.co/mkC2lQc7mi @tweet

[URochester SMD @URochester_SMD]

Using guide RNA, scientists found a way to make some genetic mutations "invisible." The findings in @MolecularCell are helping the search for treatments for #CysticFibrosis & #neurofibromatosis

Read: https://t.co/ViQWvADJvX

@CF_Foundation @GilbertFamilyFd #URochesterResearch

[URochester SMD @URochester_SMD]

A big congrats to Lynne Maquat for winning the 2023 Gruber Genetics Prize for her discovery of nonsense-mediated mRNA decay (NMD) in humans! She shares the prize w/ Allan Jacobson from @UMassChan 👏👏 #URochesterResearch #GruberPrize @The_Gruber_Fdtn @Genetics2023 @GeneticsGSA

[Maquat Lab @MaquatLab]

Congrats, Dr. Maquat!!!! #RNA #URochesterResearch

[Cold Spring Harbor Asia @CSHANews]

Registration for #CSHAsia meeting on the Now and Future of #RNATherapeutics (https://t.co/umwyakIrdn) at Awaji 🇯🇵 in June2023 is now opened! Abstracts submission by April 14!
#RNA #mRNA #siRNA #antisense #RNAtranslation #Geneediting #liposome #RNADrugs #mRNAvaccines

[URochester SMD @URochester_SMD]

Our next Dean’s Lecture Series event is happening Monday, Dec. 12 and features our very own RNA expert Lynne Maquat, Ph.D. (@MaquatLab). Details here: https://t.co/frMpivLMT2.

[Maquat Lab @MaquatLab]

Out now! The @MaquatLab paper in @MolecularCell about the #FraglieX protein FMRP, which directly binds PABP and mRNAs to inhibit translation and decay. Congrats to our lead author Tatsuaki Kurosaki, @AlexanderHewko and our @UTokyo_News_en collaborators!#URochesterResearch

[URochester SMD @URochester_SMD]

OUT NOW via @MolecularCell ⤵️ https://t.co/Ds2mjOLonK

Research by @MaquatLab, including lead author Tatsuaki Kurosaki, @AlexanderHewko and collaborators from @UTokyo_News_en

#URochesterResearch 🧵 (1/6)

[Maquat Lab @MaquatLab]

It's @AlexanderHewko 's birthday celebration-- and an extra spooky birthday cake for Halloween made by RAP Xavier Rambout in the @MaquatLab! #Halloween

[Maquat Lab @MaquatLab]

Read here about the exciting research we are doing on #FragileX with the Pröschel lab, Sakano lab, and @TeliasLab! #URochesterResearch

[Del Monte Institute for Neuroscience @URNeuroscience]

Q: What do a molecular biologist, neurotologist, geneticist, neuroscientist, & a vision scientist have in common?

A: #FragileX research & it's happening @UofR👇

Learn more in our latest newsletter➡️https://t.co/9AbVwCO6J6

#URochesterResearch #RareDisease @MaquatLab @TeliasLab

[Maquat Lab @MaquatLab]

Congrats, Dave! #URochesterResearch

[URochester SMD @URochester_SMD]

Dave Matthews and his team of biophysics, biology, chemistry & physics students (a few pictured 👇) earned a @NIGMS MIRA grant (Maximizing Investigators' Research Award) to study RNA structure modeling using physics & sequence comparison. Congrats! #URochesterResearch @UofR  👏

[Maquat Lab @MaquatLab]

Congrats, @Wagnerlab_RNA!

[URochester SMD @URochester_SMD]

Research from @Wagnerlab_RNA 👇& the Tong lab @Columbia reveals the presence of IP6 in the Integrator Cleavage Module. The work in @NatureComms opens up cellular signaling as a potential regulator of Integrator’s transcriptional control #URochesterResearch https://t.co/4odLKT2AKy

[The Nobel Prize @NobelPrize]

BREAKING NEWS:
The 2022 #NobelPrize in Physiology or Medicine has been awarded to Svante Pääbo “for his discoveries concerning the genomes of extinct hominins and human evolution.”