Mario Santer

Postdoc @DaganLab. Former PhD student @MPI_Evolbio @HildegardUecker

Theoretical evolutionary biologist interested in plasmids, evo rescue, and resistance

[Tal Dagan @DaganLab]

Imagine that you are a low-copy extra-chromosomal genetic elements that invaded a host cell. What’s your best strategy to survive? Check our new study of prokaryotic #plasmid for the answer! https://t.co/k262MGQQdI led by Johannes Effe with @MarioSanter @iwangtoknow @NilsHuelter

[Mario Santer @MarioSanter]

@LanjuLucy @PLOSCompBiol @MEKlab @HelenKAlexander Congrats!! 👍

[Nataša Puzović @natashapuzovic]

#SMBE2023 goers, interested in gene expression noise and gene regulatory networks? Come to my talk today at 14:20 at AD1! Or find me during the coffee breaks/lunches, I am happy to chat. Cheers!

[Marina Khachaturyan @zyukeriya]

I know #SMBE2023 is huge! Come see my poster on similarities and differences in the mitochondrial and plastid neutral evolution. And #eelgrass as a wonderful model organism! Tomorrow (July 25th) No. 604 in the EC venue. @DaganLab @MarioSanter @MarineEvolEcol

[Wang, Yiqing @iwangtoknow]

Arrived in Ferrara! #SMBE2023 #SMBE23 I will be presenting my poster No. 160 in the SP venue today. Looking forward to talking to you!

My work is on AMR gene content evolution in plasmid genomes driven by transposable elements. @DaganLab

[Dustin Hanke @DMHanke]

What a beautiful place to be #Ferrara. I'm glad to present my poster at #SMBE2023 #SMBE23. I will be presenting my poster No. 379 in the SP venue today in poster session 1.

I'll present my work on frequent gene non-functionalization in plasmid genomes. @DaganLab

[Mario Santer @MarioSanter]

#SMBE2023 The more, the merrier! But is that also true for the evolution of bacterial multicopy plasmids? Find out more today at my poster 36 (Castle Estense) @DaganLab @HildegardUecker @anagarona

[Ernesto Berríos-Caro @ernestoberriosc]

We are excited to announce a symposium on the mathematical modelling of resistance evolution (bacteria and cancer) at @MPI_EvolBio on 26-28 April 2023. We welcome researchers at any career stage.

Abstract submission deadline: 3 February 2023.

More info: https://t.co/jQYoJY83Gg

[Mario Santer @MarioSanter]

In polyploid prokaryotes, genetic variation can thus be maintained for a long time following phenotypic adaptation. 5/5
https://t.co/uLvbh3j2u9

[Mario Santer @MarioSanter]

New preprint on the population genetics of polyploid prokaryotes! Many prokaryotes carry polyploid chromosomes or multicopy plasmids. In collaboration with @annecmg, @DaganLab, @HildegardUecker, we present a population genetics model for multicopy replicons in prokaryotes. 1/5

[Mario Santer @MarioSanter]

Numerical simulations and analytical approximations show that it emerges if the copy number is high and selection strong. 4/5

[Mario Santer @MarioSanter]

@diebner_h @HildegardUecker @EvolTheoArne (2/2) To avoid any misunderstanding, we have added a corresponding explanation in red. Thank you for your feedback!

[Mario Santer @MarioSanter]

@diebner_h @HildegardUecker @EvolTheoArne (1/2) That is right. For simplicity, we do not consider recoveries, and our simulations resemble an SI and not an SIR model. They are meant to demonstrate the effect of control measures on the rate of spread.

[Nicholas Noll @n_b_noll]

@richardneher @ivan_aksamentov and I have updated https://t.co/w5SxsNuGyG to model finite ICU bed space within hospitals. Please take a look to see our updated predictions. And for those interested, please head over to our Github to help out and give suggestions!

[Bernd Blasius @BerndBlasius]

Comparing the time course of COVID-19 epidemic between Germany and Italy reveals that growth rates in Italy have been decelerating over the last 3 weeks, while that in Germany are more or less constant since 13 days
(https://t.co/HYITyjqJIH)
#COVID19

[Hildegard Uecker @HildegardUecker]

This is an article about human viruses that we wrote for school students last year. It contains a little project about disease spread and vaccination at the end. Maybe someone finds it useful for teaching purposes.
https://t.co/zSM1T0RrrR