Irene B Maroto

[Carlos Costas Insua @Carlos_Costas]

🚨 Our latest work is out in @SfNJournals!
Led by the amazing @MarotoIrene with key support from @MarsicanoLab & @BaufretonJerome.
GAP43 on corticostriatal terminals restrains novelty-induced hyperactivity in mice. 🧠🐭
Read more: https://t.co/35uoHHHzIH
#Neuroscience #Research

[Carlos Costas Insua @Carlos_Costas]

Our new follow-up on GAP43-CB1R complexes. Kudos to @MarotoIrene @Moreno_G_Estefa and the rest of the teams @leyreuriguen @BBM_UCM @UniBarcelona @unicomplutense
https://t.co/HVQYcjDSoQ

[Carlos Costas Insua @Carlos_Costas]

This was a huge team effort including @Moreno_G_Estefa @leyreuriguen @MarotoIrene and many other twitterless people. Special congratulations to my fellow colleague Alba Hermoso, who shares the first authorship

[Irene B Maroto @MarotoIrene]

By state-of-the-art electrophysiology experiments, we showed that the interaction impairs CB1R-mediated suppression of mossy cell to granule cell transmission, leading to the inhibition of cannabinoid mediated anti-convulsant activity in mice! 4/4

[Irene B Maroto @MarotoIrene]

I´m thrilled to share our work published in @NatureComms https://t.co/A3Wb5jbU4w in which we identify GAP43 as a synapse type-specific interacting partner of cannabinoid CB1 receptor that inhibits its function and anticonvulsant properties! Check below for a short summary...1/4

[Irene B Maroto @MarotoIrene]

Within the brain, we narrowed down the CB1R-GAP43 interaction to one specific excitatory synapse of the hippocampal dentate gyrus: the mossy cell to granule cell synapse, involved in hyperexcitability-driven seizures. 3/4

[Carlos Costas Insua @Carlos_Costas]

Check out our latest work in @NatureComms https://t.co/d9DZtWaIWN Amazing project led by @MarotoIrene unveling an unprecedented CB1R-GAP43 complex that fine-tunes hippocampal CB1R neuromodulation . From the cannabinoid signalling lab at @BBM_UCM @BiologiaUcm @unicomplutense

[BryanRoth @zenbrainest]

Now this is interesting:
https://t.co/J7K9qqJs33

[Diana Morant @DianaMorantR]

La plataforma #CientíficasEInnovadoras crece en la #SemanaCienciaInnovación. Ya tenemos añadidas a más de 230 grandes mujeres premiadas que trabajan para lograr un futuro mejor. El mejor talento con nombre de mujer. Inspiración para futuras generaciones.

https://t.co/V1Q5I6lBtf