Peter Masel

[Avraham Eisenberg @avi_eisen]

https://t.co/tiveQPhoOC

cannot stress how much this was an actual Softbank slide

[Bryan Johnson @bryan_johnson]

Some of us will live forever.

And if you’re reading this, that may or may not be you.

I am so bullish on this that I just renamed my company to Immortals.

Below:
+ why I think this
+ early signs of success
+ how to increase your odds

Yes, I know this sounds crazy.

Immortality has been an ambition for humanity since the beginning of recorded history.

The immortality I’m referring to is specific: increases in life expectancy will outpace the rate of aging. Meaning, we will no longer, by default, expect to die of natural causes.

I believe this for three reasons.

#1: Immortality already exists

Biology can reverse some features of aging, and in a handful of organisms escape it almost entirely. For example, a sperm and an egg from two people in their 30s carry the legacy of bodies that have aged for decades (the egg in particular has been arrested inside the mother since before she herself was born), yet they combine to produce an embryo that resets the aging clock to zero.

The immortal jellyfish goes further and resets itself within one lifetime, reverting its adult cells to an earlier stage through transdifferentiation and starting its life cycle again. And in the lab, scientists have begun doing this deliberately, making induced pluripotent stem cells (iPSCs) from mature adult cells such as skin fibroblasts, and using partial cellular reprogramming to turn the clock back in the tissues of living animals.

#2: AI offers new potentials

Biology is a hard problem. For most of history that complexity was beyond native human capacity. AI was made for this complexity. The clearest demonstration so far is protein folding. Predicting the three-dimensional shape a protein folds was an unsolved problem for roughly fifty years, and it mattered because a protein's shape determines what it does in the body.

DeepMind's AlphaFold2 effectively solved it in 2020, reaching a median accuracy of 92.4 out of 100, a level long thought to require the slow, painstaking work of crystallizing a protein and solving its structure by X-ray crystallography. It then released predicted structures for over 200 million proteins, nearly the entire catalogued protein universe, in a fraction of the time anyone expected.

#3: Early signs are encouraging

These aspirations are not imaginative. With the current tools in biotech Sid Sijbrandij, the co-founder of GitLab, was diagnosed with an aggressive bone cancer, osteosarcoma in his vertebrae. He treated his own disease like an engineering problem, he used AI to help direct several experimental, personalized therapies in parallel and drove the cancer into remission after standard medicine had given up. Around the same time, an Australian named Paul Conyngham, with no medical or biology background, did something similar for his dog. He used AI to help design a personalized mRNA vaccine targeting the specific mutations in his dog's tumor, and after it was given alongside another immunotherapy and within a few months the main tumor had shrunk by roughly three-quarters.

How to increase your odds…

I. Don’t die in the meantime

We don’t know when these longevity therapies will become available. Your goal is to be around when they come out. Buy yourself as much time as possible by looking after your body to the best of our scientific knowledge. Good diet, sleep, exercise will get you 80% of the results.

II. Find your achilles

Longevity therapies will likely be outcome specific. Individual specific drugs/therapies that target specific things like…

> prevent and remove arterial plaque
> prevent and reverse neurodegeneration
> specifically target and eliminate cancers, or pre cancerous legions
> prevent frailty and muscle loss, and regain muscle mass, strength and, bone density
> reverse skin aging
> rejuvenate eye health
> restore lost hearing
> etc

We don’t know what therapies will be available first. Your goal is to find what your body is struggling with most and keep that problem at-bay until a therapy is available that can fully cure or reverse it.

For example, do you struggle with cholesterol? Blood glucose control? Cognitive decline? Find your achilles heel and reduce your risk systematically.

III. Invest in the future

There are three macro trends happening on planet earth right now, and the people who bet on these areas have the highest risk + reward.

> AI
> Immortality
> Energy

As we know, power comes in many forms: money, social, political, health, etc. Those that can collect power in these fields will have the greatest chance of positioning themselves in the Immortal future.

With time, Immortal therapies will become broadly available.

If you’re reading this: don’t waste your chances by burning down your life points on a yolo-like mentality. Grind culture, addiction, social media pollution, fast food, porn, alcohol, these are all corporations turning your life into their profit. This is the Die Economy.

My company Immortals has the sole objective of turning your time, attention, and life into more healthy, functional, and prosperous minutes, days, and years. The Don’t Die Economy.

Good luck.

[Jesse Myers @Croesus_BTC]

STRC down to $82.6 today. Here's my read:

1. Strategy is fine. If everything stays as is, they can pay STRC dividends for 32 years. If BTC appreciates at ~2% CAGR, they can pay dividends indefinitely.

2. Why the sell-off? This appears to be a liquidation cascade.

Over the last 6 months, the narrative became that STRC volatility was reducing, and price began to spend all its time in $99-100 range.

This invites leverage. If you expect the price to always be north of $95, you can take on 20x leverage with your portfolio to buy more STRC and dramatically increase the yield on your portfolio.

This works great, until it doesn't.

STRC is designed as a free-market asset. When attention shifted to SATA and STRC price flagged, it may have raised the attention of opportunistic short-selling hedge funds.

By shorting aggressively, they could push the price down and start triggering margin calls and liquidations from folks who aggressively levered up their STRC positions.

The price action today is a clear liquidation cascade, rapidly pushing prices lower, in turn triggering additional liquidations.

3.
What happens now? The market will heal itself.

Opportunistic hedge funds will recognize that this is a firesale and the fundamentals are unchanged for STRC and step in as buyers. Shorts will close, becoming buyers. Individuals are getting a tremendous entry price for long-term holding STRC shares.

Buyers at this level will get ~13.7% effective yield. If STRC trades back to $100 and they sell, they get an easy +18% return.

4.
What will Strategy do?

Strategy will likely increase the dividend rate on June 30 - maybe to 11.75% but possibly to 12%. Buyers at the current price level then would get 14.2% effective yield from that point forward.

Strategy may also step in to buy STRC shares back. They could do this by issuing new shares of MSTR (currently at 1.14 mNAV) or by taking on traditional debt and deploying those funds to buy discounted STRC shares on the market.

If/when STRC trades back to $100, Strategy could then re-issue those STRC shares. The ~$15 delta per share could be used to buy BTC as pure accretion to MSTR holders, with no net change to amplification.

No doubt that Saylor has already at least considered this, and it wouldn't surprise me if they're currently doing this.

5.
In summary...

The market is freaked out that this depeg is like Terra/Luna... but this is not an asset like that. Strategy's balance sheet determines whether STRC continues to receive dividend payments... and Strategy's balance sheet is completely unchanged.

This is a leverage wipeout.

From this, the market will learn that Digital Credit is mostly very low volatility. But because it is a free market asset, the longer that a Digital Credit instrument trades within a tight range to par... the more leverage will inevitably pile up as people get greedy.

And that creates the conditions for a leverage wipeout depeg. Following that, the instrument will make its way back to par value as the market heals itself and recognizes that the dividend payments will continue uninterrupted because the issuer's balance sheet is unaffected.

[Charles Edwards @caprioleio]

Anthropic just gave North Korean hackers a nuclear bomb today. Mythos is out.

Make sure all your software is updated and auto-updates are on.

[Stacy Muur @stacy_muur]

DeFi yield trackers worth bookmarking ↓

→ https://t.co/DaIh9NmDu0
→ https://t.co/lJoAWsrRbO
→ https://t.co/KtRPmi4TOm
→ https://t.co/QUbFg7ELXz
→ https://t.co/jDxCP4tRsg
→ https://t.co/58GJGjbnx2

[Yan Liberman @YanLiberman]

Near-term BTC price action is going to be heavily dependent on one thing:

Did Saylor sell enough BTC this past week?

If he sold zero, that’d be a massive mistake on his end and we’re probably cooked.

If he sold $1B of BTC, that helps, but realistically I don’t think it’s enough and we probably continue lower.

If he sold at least $2B, that’s where it gets interesting and sets up a bounce.

The more he sold, the harder we bounce.

My base case is that he sold at least $2B. I also think there’s a decent chance BTC bottoms into Monday if the market starts pricing in that he sold some.

Rationale:

Selling none is my lowest probability scenario. He needs the money.

He already did that weird 32 BTC “test” sale and I have a hard time understanding the purpose of it. If he was planning on selling more, all the test did was give him worse execution. If he wasn't planning on selling more, then he nuked the market for no reason. The latter seems completely ridiculous, so my guess is it was indeed a test and he was planning on selling more.

A tiny sale ($500m) is the worst of both worlds. It damages the “never sell” narrative without solving the liquidity problem. If you’re going to sell, sell enough to matter.

That’s the key here.

A material sale does two things at once. It adds real cash runway, but it also sends an important signal to STRC buyers: he is willing to sell meaningful amounts of BTC to keep funding the dividend.

That signal matters a lot.

Strategy has roughly $871M left in its USD reserve. Against the current preferred + debt cash burden, that’s only about 6 months of runway.

If he sold $1B, that takes runway from ~6 months to ~13 months. Helpful, but probably not enough. 13 months is enough to reduce near-term stress, but not enough to make STRC feel like a self-sustaining issuance product again. STRC buyers are still underwriting a shrinking cash cushion and hoping the market rallies materially within that window. I think it becomes very hard for STRC to get back to 100 in that scenario.

If he sold $2B, that takes the reserve to ~$2.9B and extends runway to roughly 20 months. That is a very different setup. At ~20 months of coverage, blow-up risk gets pushed much further out, STRC buyers can believe the dividend is properly covered by cash on hand, and the product has a real chance of trading back to 100.

It also changes how STRC buyers think about the balance sheet. They’re not just relying on new issuance to get paid. They’re backed by a massive BTC treasury that Saylor has now shown he is willing to selectively monetize to support the credit stack.

Once STRC is back at 100, the flywheel can restart.

This is the “sell to buy” point.

A large BTC sale does not just create cash runway. It can increase his ability to issue STRC, which then gives him the ability to buy more BTC than he sold.

So the hierarchy is simple:

Selling zero is the disaster scenario.

Selling too little helps, but probably does not fix the flywheel.

Selling enough to matter is what gives STRC a path back to 100 and gives BTC a reason to bounce.

[Arkham @arkham]

A well-known MakerDAO whale last week flipped the $1B mark on the total value of the collateral inside their vaults.

This whale has seen over $200M of profit over the last 2 weeks alone, and has begun taking profit into Uniswap liquidity positions.

Let's take a closer look.

[DeFi Dad ⟠ defidad.eth @DeFi_Dad]

🎙️ New @edge_pod

🏦 Why Private Credit Is Moving Onchain — And What DeFi Gets Right and Wrong About It

0:00 - Intro
2:53 - Fasanara on private credit in DeFi
10:55 - Opportunity for tokenization is huge!
16:31 - Valid concerns about private credit onchain
20:52 - Why Noon deployed into Fasanara FTAC
23:25 - How Noon manages liquidity demands
27:22 - Why infiniFi deployed into mGLOBAL
31:48 - FBG stress test on Fasanara and DeFi
43:17 - What DeFi must get right in next phase
48:04 - Real-time verification can improve TradFi
52:53 - How infiniFi is betting on private credit
58:12 - What shouldn't work well onchain
1:04:41 - Closing

🙏 Thanks to @FasanaraCapital Head of Tokenization David Vatchev, @noon_capital Founder @ag_noon, and @infiniFi CoFounder @robanon for joining us!

[CBB @Cbb0fe]

After losing faith in crypto last year, I kept asking myself what I would do today if I had to start from zero again.

And whenever I fud crypto, people ask me that question too.

Honestly, I never really had an answer.

I’ve spent the last 9 years doing nothing but crypto, and I really struggle to imagine myself identifying plays like $SNDK or $MU one year ago.

If your entire stock market information flow comes from big Twitter accounts and Bloomberg, I highly doubt you will ever build generational wealth there.

But I’ve been following @crypto_condom for a few months now and I find it very interesting.

I think that if you are willing to spend 16 hours a day grinding online, it is still possible to find alpha in some stocks before it gets officially confirmed on Bloomberg.

The hard part is filtering the noise.

There are hundreds of Twitter accounts posting tickers every single day and perma retweeting their winning calls.

You need to focus on a few stocks and become autistic about them. Follow the founders on all social media, check their interactions, track the job offers etc.

There is always a bull market somewhere.

[David Hoffman @TrustlessState]

https://t.co/5EOn4y2pdx

[DeFi Dad ⟠ defidad.eth @DeFi_Dad]

🎙️ New @Edge_Pod

🫡 Strata: Why DeFi Is Finally Ready for Risk Tranching | DeFi Frontier

0:00 - Intro
2:14 - Founding Strata
3:40 - What is tranching?
7:14 - Why tranching will now take off in DeFi
13:43 - How Strata tranches risk for yields
17:05 - Splitting yields into junior vs senior
21:49 - Screenshare of a Strata market
26:40 - Balancing senior vs junior TVL
29:26 - Tranching vs insurance
38:13 - How Strata works with RWAs
42:59 - DeFi’s big issue: mispriced yields
46:00 - How builders onboard with Strata
49:12 - Closing

🙏 Thanks to Frontera Labs CoFounder & CEO @UnQuidPro for joining us to discuss @strata_markets!

[Justin Bechler #BIP-110 @1914ad]

https://t.co/8Yg1MMUH99

[jfab.eth @josefabregab]

The opportunity cost of keeping your stablecoins idle can't be ignored.

In @aave V4, you can currently earn:

> 8.75% APY on $USDG
> 7.00% APY on $frxUSD
> 6.10% APY on $USDT
> 4.59% APY on solana:EPjFWdd5AufqSSqeM2qN1xzybapC8G4wEGGkZwyTDt1v

No lockup periods. Isolated risk. Your stables remain... hyperliquid.

No brainer.

[Markets Aurelius @0xlarpist]

how i make >100% on $55k on world markets in 3 minutes and 47 seconds

[Smartmoney_Detective @NaveenCypto]

Crosses half a Billion .

$504 Million in Total supply.

With 27% in APY at offer.

@jup_lend X @0xfluid

[Nav Toor @heynavtoor]

THIS GUY BUILT AN ENTIRE WIKIPEDIA THAT IS 100% AI HALLUCINATIONS AND IT'S OPEN SOURCE ON GITHUB

it's called Halupedia.

nothing on the site existed before you clicked. every article was generated the second you arrived.

the site has one rule: the universe only exists when you visit it.

it looks exactly like wikipedia. same fonts. same layout. same scholarly citations. same "stumble" button for random articles.

the only difference is none of it is real.

here are some actual articles currently in the encyclopedia:

> the great pigeon census of 1887
> the ministry of slightly wrong maps
> chaldic arithmetic — a branch of mathematics where subtraction is forbidden
> armund the river mapper — a cartographer who mapped 14,000 leagues of river without leaving his chair
> the society for the prevention of unnecessary tuesdays

every article page also tells you how many people are reading it right now. it says: "you alone are consulting this folio at present."

the creator's own tagline for the site is the most unhinged sentence i've read this year:

"an encyclopedia of a universe that does not exist until you visit it"

the entire backend is a single open source repo called vibeserver. one guy. one description on github: "a little webserver making things up just in time."

we built the largest knowledge base in human history and the very first thing a guy did with it was make a hallucinated mirror universe and put it on the open web.

the internet is healing.

[TokenLogic @Token_Logic]

@aave @GHO 2/ Mainnet (50,000 $GHO over 4 weeks):

✦ Normal vaults: 4,500 $GHO/week
✦ GHO/USDC (Smart Collateral/Smart Debt): 3,500 $GHO/week
✦ GHO/sUSDe + GHO/USDC: 250 $GHO/week
✦ fGHO: 4,250 $GHO/week

[Ray Dalio @RayDalio]

While Bitcoin gets a lot of attention, it hasn’t played the safe-haven role many expected. In my view, there are a few reasons why.

First, Bitcoin lacks privacy. Transactions can be monitored and potentially controlled, which is why central banks aren’t looking to hold it.

Second, it also has a high correlation with tech stocks. When investors get squeezed in other areas of their portfolio, they sell their Bitcoin to cover it.

Third, it’s a relatively small and controllable market, whereas gold stands alone. There is only one gold.

Ultimately, gold is more widely held, deeply established, and still plays a central role in the global system.

[Willy Woo @willywoo]

I ask Grok and Gemini to assess the risks investing in Strategy's $STRC yield instrument. Then I asked it to estimate a yield that would fairly compensate the investor for the risk undertaken.

Both concluded 11.5% was underpaying for the risk.

Grok: 17-22% APY
Gemini: 16% APY