Our work interrogating chondrocyte mechanotransduction and co-opting TRPV4-signaling to develop mechanogenetic cartilage is out today in @ScienceAdvances - great team effort on this one with @LPferdehirt and the @Guilak_Lab crew! @Farsh_G https://t.co/LQcHKmVW1p
Is there anything TRPV4 can't do? Our paper just out in @StemCellsJournl by Vince Willard shows that #TRPV4 is not just a marker of chondrogenesis, it also regulates it in #iPSCs! w/ Holly Leddy, Daniel Palmer, Chia-Lung Wu, & Wolfgang Liedtke @Regeneron https://t.co/ydVXNcPP19
Can cells be rewired to deliver on-demand drugs that fight fluctuating #inflammation? We bioengineered anti-cytokine implants using #CRISPR#synbio that mitigated #arthritispain, #jointdamage, bone erosion and inflammation in mice: https://t.co/MCoNLJV324
@Farsh_G @WUSTL_Rheum
Congrats to @mollyklimak! Her review on “Immunoengineering the next generation of arthritis therapies” is now out in @ActaBio! Here we review some of the newest cellular, gene, and biomaterial approaches for immunoengineering to treat OA or RA. https://t.co/730uTnBqDM
And here is the press release on @WhasilL's paper on Piezo sensitization in chondrocytes by IL-1! Excited to see where she next takes this project in her lab! https://t.co/QoYZOv0PfJ
Great new paper by @WhasilL showing how inflammation provokes cellular mechanosensitivity through Piezo1. Great working with Wolfgang Liedtke’s lab, @mcnultylab, @AliSavadipour, @Farsh_G
Congrats to Dr Whasil Lee @WhasilL for her latest #Piezo paper out in @PNASnews!!! She showed IL-1 enhances Piezo1 function, making chondrocytes more sensitive to loading. Great collab with Liedtke lab @MaybeItsBob@AliSavadipour@mcnultylab & others
https://t.co/jER6ybbJe6
OK I found my words. I am howling with rage tonight at the rising tide of violence and hate crimes directed towards Asians in America, punctuated by the horrific shootings yesterday in Georgia at 3 Asian-owned business that claimed 8 lives, including those of 6 Asian women.
Come join us! InPrint is a great opportunity to advance your scientific communication skills while helping out the @WUSTL research community.
@WashUBME@washu_ortho_res@wustlcrm