Mehandru Lab @MountSinai

We study the human mucosal immune system with a focus on IBD and HIV to determine mechanisms of disease pathogenesis and predictors of therapeutic response

[Iannis Aifantis @iannisaifantis1]

Out today the last piece of work that Maria Guillamot did in our lab in a collaboration with @AWeinstock and @DrShrutiNaik (who lead the study) showing type I interferon (IFN)-mediated activation of hematopoietic stem/progenitor cells resulting in profound changes to systemic host responses...such studies could impact the way that we connect inflammation, autoimmunity to hematopoietic stem cell biology, differentiation and dysfunction...
https://t.co/2wqLpR8E7u

[Mehandru Lab @MountSinai @MehandruLab]

@nkg2d1 @uoftmedicine @UofT @Es_cheri_chia Amazing work! Many congratulations!!!

[Arthur Mortha @nkg2d1]

New result from #theonlylabever @uoftmedicine @UofT . open access link here (until Feb 2025) https://t.co/UYuh343tFH
Many thanks to @Es_cheri_chia for the excellent editorial work. Hope you will find it interesting.

[Mehandru Lab @MountSinai @MehandruLab]

@IlievLab Amazing work, @IlievLab. Super congratulations!!!

[GiulianaMagri @GMagri_Immuno]

📢Thrilled to share our work on the ontogeny, reactivity, and function of #IgA subclasses in homeostasis and #IBD! Huge thanks to Andrea, all our amazing collaborators, and @JExpMed for their support throughout the extended revision process! It's time to celebrate🥳!

[Journal of Experimental Medicine @JExpMed]

Tejedor Vaquero, Neuman, Mehr, Cerutti, @GMagri_Immuno @HMar_research et al. show that gut IgA1 & IgA2 subclasses co-emerge early in life, largely derive from clonally related and somatically mutated plasma cells in adults, & show unique changes in #IBS. https://t.co/B7u4GIs7Vg

[IBD Leuven @ibdleuven]

#Eosinophils mitigate intestinal #fibrosis while promoting inflammation in a chronic DSS colitis model and co-culture model with fibroblasts by @jacobsinge8 @DeleuSara @gmatteoli1978 @SeverineVermei1 @VanuytselTim @bverstockt @TARGID_KULEUVEN

https://t.co/ShxZyY3hH6

[Jean-Frederic Colombel @JeanFredericCo1]

Anti-integrin αvβ6 autoantibodies are increased in PSC patients with concomitant IBD and correlate with liver disea… https://t.co/FMxox5aOjL

[Dr. Jen Gommerman @JenGommerman]

A fantastic day celebrating the 40th anniversary of the discovery of the TCR. Check out this T cell speaker photo which includes co-discoverers Tak Mak and Mark Davis. Thanks @UofT, @uoftmedicine, @ImmunologyUofT, @thePMCF for your support.

[Mehandru Lab @MountSinai @MehandruLab]

@MiriamMerad @Inserm Super congrats, Miriam!

[GiulianaMagri @GMagri_Immuno]

Please RT 🙏!📢My lab at @UniBarcelona is seeking a highly motivated postdoc to lead an exciting new public-private collaborative project (UB, CRG, CSIC, OrikineBio) aimed at testing a potentially game-changing therapy for IBD. If interested, please contact me at [email protected].

[Miriam Merad, MD, PhD @MiriamMerad]

Very honored to receive the International @Inserm Prize today at the French Embassy in DC. Great evening with @Inserm CEO Didier Samuel, Ambassador Lilli, and wonderful colleagues, celebrating France/US partnerships and our shared commitment to advancing science across borders.

[Science Immunology @SciImmunology]

New research from @MehandruLab describes the depletion of germinal center B cells and IgA+ plasma cells in the #GI tracts of people living with #HIV. @francescacossa1

Read more in Science #Immunology: https://t.co/AddkkyWKbD

[Bhardwaj Lab @BhardwajLab]

Celebrating our PI @NinaBhardwaj! What an amazing week; elected to the National Academy of Medicine on Monday, then selected as Inventor of the Year (Mount Sinai Innovation Awards)…we are all so proud to be in your lab! Cheers 🥂!

[Mehandru Lab @MountSinai @MehandruLab]

@BhardwajLab @NinaBhardwaj Super congrats, Nina! This is incredible

[Arno Bourgonje @BourgonjeArno]

Out now 🚨 in @AGA_Gastro is your latest update on selective IL-23p19 inhibition in IBD! Amongst other topics featuring discussion of pathogenesis, PD/PK, efficacy, safety, positioning, and more! Together with @JeanFredericCo1 @MehandruLab & @ryanungaro https://t.co/E6ac1n4Zf8

[Mount Sinai Division of Gastroenterology @MountSinaiGI]

Every year, @JeanFredericCo1 hosts the GI Division #IBD Retreat to address challenging topics in #IBD. We're proud to keep the tradition going this year at IBD Retreat 2024! Register here to join: https://t.co/W9RDBvqc6U

[Mount Sinai Division of Gastroenterology @MountSinaiGI]

Great work from @MehandruLab & congrats on this #PosterOfDistinction at #DDW2024! @divyajha_phd walks us through the intricate role of cellular dynamics within the epithelial compartment and their impact on treatment responses of therapies used in #ulcerativecolitis management.

[Dr. Shruti Naik @DrShrutiNaik]

🙏🏼🙏🏼🙏🏼pumped for the naik lab move to @SinaiImmunol and to be part of this vibrant and exciting community of immunologists and for the breakthrough discoveries we will make together @MiriamMerad @brianbrown #naiklabmoveuptown

[Lipschultz Precision Immunology Institute @SinaiImmunol]

🍾CONGRATULATIONS🍾 to the fantastic @DrShrutiNaik on winning this year's @LeoFondet award in recognition of her visionary skin research program encompassing dermatology, neuroimmunology and more! Read all about it >>> https://t.co/wIAZrRPMCA