Meier Lab - MiBioEng @ HPC

Microfluidic Bioengineering group at @pioneercampus / HMGU in Munich.
🧫 Organoids-On-Chip 🧬 scRNAseq 🔬 Pancreatic islet research

[PioneerCampus @HelmholtzMunich @PioneerCampus]

Spring arrived at our @HelmholtzMunich research Center (in front of PioneerCampus & Diabetes Center, respectively). First outdoor lunch for @Meier_Lab (note the energising spring bulbs/flowers left hand side corner).🌼☀️

[carsten marr @MarrCarsten]

Congrats Scott and @dominik_waibel for this feat!!! A truly inspiring interdisciplinary work with @Meier_Lab between @PioneerCampus and @CompHealthMuc at @HelmholtzMunich

[Meier Lab - MiBioEng @ HPC @Meier_Lab]

Neubau am Helmholtz Zentrum München soll Pioniergeist wecken | via @BR24

In the end our part was cut from the final segment, but here's the report from BR about the opening of our beautiful new @PioneerCampus building!

https://t.co/RmB5uLO270

[Meier Lab - MiBioEng @ HPC @Meier_Lab]

Check out a little clip that the @BR_Presse made in our lab - today (Wed, 12.07.) at "Rundschau", 18:30.
We talk about our science and how the new @PioneerCampus building will impact our collaborative work environment!

[Meier Lab - MiBioEng @ HPC @Meier_Lab]

@RongFan8 @johwirth @celia4science @NatureComms @ninahuber21 @Kelvyinzinho Thanks, Rong!

[Johannes Wirth [email protected] @johwirth]

I am excited to present multiplexed Deterministic Barcoding in Tissue (xDBiT)🎊. As an extension of #DBiTseq it allows the generation of #spatial #transcriptomics datasets of nine fixed tissue sections in parallel. Paper finally out on @NatureComms📜https://t.co/DfY0UXjBAa 1/6

[UNIVERSITÄT LEIPZIG @UniLeipzig]

Dr. Matthias Meier (@Meier_Lab) ist seit Kurzem Professor für Biochemische Zelltechnologie. Er forscht daran, menschliche Organe mittels Stammzellen außerhalb des Körpers nachzubauen, um Therapien für metabolische Krankheiten zu entwickeln. #UniLeipzig: https://t.co/tgRMeGm7YB

[ninahuber @ninahuber21]

🎓PhD - done ✔️🥳
Many thanks to the @Meier_Lab, @PioneerCampus and @LabWolfrum for supporting me all the way through! It’s been a wonderful and exciting journey - I learned a lot, met inspiring #scientists, and had the most amazing colleagues 🤩🔬🧫💻💃🏼

[Helmholtz Munich | @HelmholtzMunich @HelmholtzMunich]

📢Research Highlight🧪:
Organ-on-a-Chip

❗️The number of possible applications for micro-organs is immense. Fundamental #research and #stemCells for cell replacement therapy are just two examples.

👉Learn more in our story:
📑https://t.co/yKVfyftjer

#diabetes #organoids

[Kelvin Yin @Kelvyinzinho]

Attending the #IRBBarcelona conference, this time presenting our poster on using multiplexed #DBiTseq (xDbit-seq) to study #spatial transcriptomic changes in #liver #zonation during #ageing. This study was made possible with @johwirth @MolAgeingLab at the @PioneerCampus.

[PioneerCampus @HelmholtzMunich @PioneerCampus]

Extremely proud😊 Summa Cum Laude for our first @PioneerCampus Graduate
Sandra Wiedenmann @Meier_Lab🎇🎉🥂
✅VIP @natBME paper https://t.co/XTGsmxNoWz
✅hum pancr. duct-like organoids for unmatched insights into deadly #cancer
✅achieved in time & style👏
https://t.co/WiIEXZvObG

[Meier Lab - MiBioEng @ HPC @Meier_Lab]

When we couple #Bright2Nuc with #TrackMate, we can track stem cells in the live 3D cultures using bright-field live imaging.

[Meier Lab - MiBioEng @ HPC @Meier_Lab]

More📜!
Introducing #Bright2Nuc: A label-free 👨‍💻#deeplearning method to predict in-silico nuclear staining from just bright-field images of on-chip 3D #iPS cultures! (Morphology - Differentiation - Tracking)➡️https://t.co/iybwszixB5
Great work by Scott Atwell and @dominik_waibel.

[Meier Lab - MiBioEng @ HPC @Meier_Lab]

With #Bright2Nuc predictions, coupled with #StarDist for segmentations, we can predict the differentiation state of the stem cells directly from the bright-field images, without the need for any additional stainings.

[PioneerCampus @HelmholtzMunich @PioneerCampus]

Highly successful multiplexing & generalization of #spatially resolved #transcriptomes in tissue sections ✅preserved #image features ✅#Scanpy integration👏🏻
-most valuable advances of spatial toolbox
-commendable efforts across @PioneerCampus @Meier_Lab @celia4science @caina89🎉

[Meier Lab - MiBioEng @ HPC @Meier_Lab]

We are proud of @johwirth and his massive improvement to #multiplexed #SpatialTranscriptomics: #xDbit, based on #DbiT - Check out his thread 👇 (and the preprint📜 at https://t.co/IO5kiEFZh1).

[Johannes Wirth [email protected] @johwirth]

I am very happy to present multiplexed Deterministic Barcoding in Tissue (xDbit)🎊. As an extension of #DBiTseq it allows the generation of #spatial #transcriptomics datasets of nine fixed tissue sections in parallel. Preprint is now out on biorxiv📜: https://t.co/4OESTDLz3z. 1/4

[Meier Lab - MiBioEng @ HPC @Meier_Lab]

What is a #pioneer?
What makes the #HPC environment so special?
Find out what our Investigators are passionate about in our new, beautiful video portrait.

https://t.co/xNurqXuCdY

@PioneerCampus @bioeng22 @helmholtz_de @helmholtz_en @caina89 @Boyan84 #ScienceTwitter

[PioneerCampus @HelmholtzMunich @PioneerCampus]

📣Delighted to share FREE REGISTRATION LINK @BioEng22! Virtually stream our plenary program👍 https://t.co/fJeC9Ba1Io
@HelmholtzMunich @MIBE_TUM @Health_talents @CeNS_LMU @GeneCenter_LMU @natBME @NatureBiotech @embl @Caltech @MRC_LMB @DKFZ @cziscience @wyssinstitute @MPI_Biochem