There is not much I can add to what Eva @FrickelLab says here. Don’t take time for granted, life can be short. Leo lived and loved everyday to its fullest. There are no words to describe how much we miss our little boy 💚
This points to a direct, regulated interaction between viral proteins and the host lipidation machinery. Thank you to co-authors @ayakimovich, @MercerLab and Ingo Drexler
🔥 Open postdoc position in human inflammation-driven control of infection!
Join me at the University of Geneva, Switzerland this summer as I’m moving my Wellcome-funded research activity to the Department of Microbiology and Molecular Medicine!
Please RT (1/5)
The main story of my PhD research project is finally out in @JCellBiol today!
https://t.co/ZgGgFW1ksJ
We were looking at how Vaccinia virus circumvents host immunity by disabling the autophagy machinery through depletion of sequestome-like receptors (SLRs). For a 🧵see below:
Paper out with former @LMCB_UCL colleagues @SamolejJ and @MercerLab
Cardiac glycosides inhibit early and late vaccinia virus protein expression - https://t.co/itP6JACAXD
And another one for @SamolejJ!
Here he shows how cardiac glycosides (think toad venom) inhibit poxvirus infection. Just out in JGV @MicrobioSoc
https://t.co/UrFJc1WsZv
Great working with @StrangVirusLab and @EM__Ian once again!!
Bisbenzimide compounds inhibit replication of prototype and pandemic potential poxviruses! @SamolejJ has extended our understanding of these novel poxvirus inhibitors @StrangVirusLab@MercerLab@ayakimovich mpox work by @cvr_crush https://t.co/n78cMEddwH
Congratulations to @SamolejJ who shows that bisbenzimides block replication of prototype (vaccinia) and pandemic potential (mpox) poxviruses!
Just out in @JournalSpectrum
https://t.co/Pjjc9DkVpt
Excellent collaboration with @StrangVirusLab@CVRinfo@lifearc1 and @ayakimovich
Really happy to see this work out and peer reviewed. Thanks a lot to everyone involved.
Here is a happy bleb to entice you into reading our deep dive into vaccinia virus binding!
Congratulations to @laurapokorny who shows that virus binding proteins aren’t just for binding!
Just out in @emboreports
Thanks to all who contributed! @JemimaBurden@yorgomodis@D4V1D_4 Becky Bamford,Kendra Leigh,Pooja Sridhar,Timothy Knowles
https://t.co/myOFOrEgJN
Today we opened the wonderful play ship for the @HanburySchool children in Leo’s memory. 💚 All made possible by resources, work and enthusiasm of our friends, community and the school. 😍 We are grateful Leo’s ship will bring years of fun to the kids. 🙏
💥 Out now @ScienceMagazine. @DanielHFisch solves the mystery of bystander cell protection during infection. An exciting mechanism, cells are so smart! PIM1 controls GBP1 activity to limit self-damage and to guard against pathogen infection | Science https://t.co/shrDXBq53Q
The @WorcCathedral Christmas Tree Festival features trees decorated by local schools & other organisations.
Ours celebrates the life of Leo and aims to reflect things he loved; nature, the colour green and the great outdoors.
Admission is free until 8 Jan: https://t.co/RI7bri68qu