Miranda G.

Flow Cytometry nerd, Boy Scout mom and wife of a scientist.

[Gunderlab @gunderlab]

We published a paper out today in @Cancer_Cell. You can find a short summary here: https://t.co/ddp8KICfiz
https://t.co/R1FIXhRUTO
Congrats to @kirschstein13 and all the authors! @NIH funded research ��🙏@OSUCCC_James @OhioStatePIIO @OhioStateSurg

[Pelotonia Institute for Immuno-Oncology @OhioStatePIIO]

🚨 New publication alert in @Cancer_Cell from @gunderlab & team!

Their study revealed that #myofibroblast programming (the most common fibroblast phenotype in #pancreatic_cancers) transcriptionally represses differentiation into fibroblastic reticular subtypes that are necessary to form #tertiary_lymphoid_structures in #tumors.

Blocking these myofibroblast differentiation signals combined with agonizing lymphotoxin beta receptor reverses this, thereby inducing TLS and promoting anti-tumor immunity.

🧠These findings help us understand how to overcome resistance to TLS formation order to increase response to #immunotherapy.

Congratulations to the team!

Read More: https://t.co/2ytpJvdyMI

@OhioStateSurg @OhioStatePIIO

[Ohio State Wexner Medical Center Surgery Dept. @OhioStateSurg]

Congrats, @gunderlab! #OhioSateSurg researcher Dr. Gunderson will use the five-year grant from @theNCI to examine how clusters of immune cells function in pancreatic tumors in the hope to promote immune responses and improve outcomes in patients with #PDAC.

[Miranda G. @MirandaGcrest]

@gunderlab You're going to get me in trouble.

[Miranda G. @MirandaGcrest]

@gunderlab @OhioStateSurg Looking good!

[Miranda G. @MirandaGcrest]

@gunderlab @OhioStatePIIO @Zihai @OhioStateSurg @BernardAFox @ChilesResearch @timpawlik @QinMaBMBL @ZCMlab I am so proud of you. We got this.

[Miranda G. @MirandaGcrest]

Well, crap. https://t.co/WaZG3Du7vT

[Pelotonia Institute for Immuno-Oncology @OhioStatePIIO]

The #PIIO is building a culture that prioritizes mentorship, training & collaboration. Passion & curiosity drive us. Interested in tertiary lymphoid structures? Want to study intratumoral B cells & how they relate to other cell types? DM @gunderlab for details on open positions!

[Miranda G. @MirandaGcrest]

@gunderlab Our new hires start with a queue of over 100 training modules. "Welcome to the team. See you in a month when we can start training on your real job."

[Gunderlab @gunderlab]

Do you want a career in cancer immunology and immunotherapy? Do you want to take a leading role in pursuing that career? We study B cells, pancreatic cancer (and others), and want to hear about your ideas. Gunderlab is hiring! DM me.
https://t.co/B1HsxbE0sD

[Pelotonia Institute for Immuno-Oncology @OhioStatePIIO]

Member Spotlight: @OSUWexMed @OSUCCC_James #PIIO researcher Dr. Andy Gunderson (@gunderlab) asks why the immune system fails to control pancreatic cancer, and works to identify novel pathways to target with #Immunotherapy. He also rides in @pelotonia!

[Miranda G. @MirandaGcrest]

@punkrockscience My dog often nurses in his sleep, with a curled tongue and sucky sounds.
He's 10.

[Gunderlab @gunderlab]

https://t.co/fD053YIBm2
"...What is academia even offering any more?”
“It’s the way we’re treated by PIs, by senior management and by academia in general,” he says. “People don’t feel valued by anyone in the system.”

[Miranda G. @MirandaGcrest]

@kevinmawright Touchy subject.

[Miranda G. @MirandaGcrest]

Watch out world, he's got a lab and a Twitter account!

[Gunderlab @gunderlab]

Fun day mingling with the Surgery Department! Big thanks to Megan and @timpawlik for the invitation and sharing your home with us. Special guest appearance by @Brutus_Buckeye!

[Brian Searle @briansearle]

Hi #teammasspec, we're hiring a computational Post Doc Scholar in the Searle Lab at OSU! Come train with us in bioinformatics, develop new proteomics tech, and build commercial-quality software, all while working on fighting cancer with the immune system! https://t.co/SPXswsa0bA

[Miranda G. @MirandaGcrest]

So proud of this man!

[Timothy M. Pawlik @timpawlik]

Excited that Andrew Gunderson, PhD started this week in Division of Surgical Oncology @OhioStateSurg as an #Immunology scientist. His research interests include regulation of adaptive immunity, B-regulatory cells, and TGF-β biology. Welcome to a new #Buckeye! ⭕️🙌-🙏⭕️

[Timothy M. Pawlik @timpawlik]

Happy to share that Andrew Gunderson, PhD, will be joining @OhioStateSurg as an immunology scientist in the Div of Surg Onc on May 1. Dr. Gunderson’s work focuses on regulation of adaptive #Immunity and immunoregulation relative to cancer pathogenesis and treatment. Welcome! 👍

[Miranda G. @MirandaGcrest]

@Carbone_Lab Best Adventure! Congratulations!

[U.S. FDA @FDA]

Today, FDA expanded the EUA for the Pfizer-BioNTech COVID-19 Vaccine for the prevention of #COVID19 to include adolescents 12-15 years of age. FDA amended the EUA issued on Dec. 11, 2020 for administration in individuals 16 years of age and older. https://t.co/3ROLW8WXwL