@AKECassels It is hard when the issues are hiding in plain sight. Did the GI say anything about dose strength? Using the lowest dose possible? How many of broken bones but weren't aware their PPI could have been the cause? #AppleQD
Heartburn drugs linked to fatal heart and kidney disease, stomach cancer | FirstWord Pharma https://t.co/m19lLnACiI. And patients are still being prescribed double the FDA indicated dose of #Dexilant because Drs were told by reps to give 60mg! #AppleQD.
Improper Proton Pump Inhibitor Prescriptions Criticized. PPIs are one of the largest classes of medications, should you still be on it? At what dose? #AppleQD https://t.co/Uhcus7u56q
ICYMI: #UBC TI Therapeutics Letter 111 on proton pump inhibitors suggests clinicians "consider deprescribing PPIs after 4 weeks of treatment when symptoms have resolved, and there is not a life-threatening condition" https://t.co/kxIMd39iWQ #DrugEvidence#TIEvidence#heartburn
"FDA Approved" says almost nothing about a drug's safety/efficacy.
Gets 75% of its budget from drug industry/dances to its tune/rejects almost nothing.
#FDA just another marketing arm of #pharma- no longer protects public.
MDs & patients must beware.
Certain drugs lead to bone fractures. #PPIs are a big one. Are you taking the right dose? #Dexilant#AppleQD. Hip fractures are deadly for many seniors - CNN https://t.co/0xJKBK3uh7
Modern PPI use raises oodles of questions. CIHI says chronic use of PPIs in seniors in BC is 9%; In Ontario it's 24%; Quebec it's nearly 30%. Such variation suggests overdiagnosis. https://t.co/wWLe8fbxI2 @Deprescribing@Drug_Evidence@DrRitaMc@DrToddLee@LessIsMoreMed
This is eye-opening! I think we need to remind kids that we are 60%+ water.
1-in-5 US Kids Drink No Water During a Given Day https://t.co/rXtmZiIYmU via @medscape
@RosenthalHealth When healthcare becomes more about making money and less about patient outcomes it gets confusing, like when math becomes more letters than numbers. I loved the book!
Proton pump inhibitors (drugs like Losec/Nexium/Prevacid) treat acid reflux or peptic ulcers. But studies on these typically do not exceed 8-12 weeks of therapy. So why do doctors prescribe them longterm to seniors? https://t.co/npdAzuHeFO @ChoosingWiselyCA RT @AKECassels
Nearly half a million BC citizens took a PPI last year, many of them chronically. Yet this is a national concern because other parts of Canada have rates that are 2-3 times ours. https://t.co/O9XfA9nX08 @picardonhealth@carlyweeks@kellygrant1@theresaboyle@jesse_mclean
US Taxpayers paid the bill for research but Big Pharma challenges the patent and makes $3 Billion. #Truvada Low R&D should mean low price.
Washington Post Examines Patent Rights Of HIV Prevention Drug Developed By U.S. Government, Made By Gilead https://t.co/ipahmgXSKl