Monsonego Lab

Immune regulation, autoimmunity, aging, neurodegenerative diseases, chronic stress, glial biology, T cell therapy

[Monsonego Lab @MonsonegoLab]

So proud of our PhD student Michael Grinberg (Borenstein) @grinbmic for winning 3rd place at #BIOMIX2025 with her innovative project Tromby!
Huge thanks to @tevapharm for the support.

[Dr Singularity @Dr_Singularity]

Israeli scientists may have just uncovered a key to slowing down aging.

They isolated a rare type of immune cell that actively hunts down and destroys senescent “zombie” cells, the toxic junk that builds up as we age.

These cells are abundant in super centenarians, and when removed in mice, the animals aged faster and died sooner.

This could be a real biological lever for slowing aging, a step toward immune driven longevity.

[Dr Singularity @Dr_Singularity]

paper https://t.co/mwjYq478Pe

[Dr Singularity @Dr_Singularity]

Every day we see some crazy, almost sci-fi, anti aging progress

Neuroscientists discovered a special type of immune cell that seems to slow aging by clearing out harmful senescent (“zombie”) cells.

These cells are found in high numbers in super centenarians, and when removed in mice, the animals aged faster and died sooner.

The finding suggests longevity may rely on an age adaptive immune system, and could lead to new anti aging therapies.

[Prof. Dr. Güner Sönmez @DrGunerSonmez]

Yaşlanmayı yavaşlatmada kilit rol oynayabilecek özel bir bağışıklık hücresi alt grubu keşfedildi.

“CD4-Eomes” adı verilen bu T hücreleri, vücutta biriken zararlı yaşlanmış (senescent) hücreleri temizleyerek kronik iltihabı azaltıyor ve bağışıklık sistemini dengede tutuyor.

[wafy fahim @wafyfahim1]

CD4 T cells acquire Eomesodermin to eliminate scencent cells

https://t.co/Bo5VLAoZD3

[Longevity @LongevityTao]

Scientists Have Discovered a Special Type of Immune Cell That Slows Aging . The team found that CD4 T immune cells transform into assassins of the damaging tissues when biological aging is detected in the body.

The new fighters, called CD4-Eomes https://t.co/vDnCU1ysVN

[Science Academy @Academ18Academy]

Neuroscientists find immune cells that may slow aging

Prof. Alon Monsonego of Ben-Gurion University of the Negev found that T helper lymphocytes, which are immune cells involved in regulating the body’s defenses, shift in function as people grow older.

https://t.co/Zuc9NkbS5G

[Agingdoc🩺Dr David Barzilai🔔MD PhD MS MBA DipABLM @agingdoc1]

CD4 T cells acquire Eomesodermin to modulate cellular senescence and aging

"CD4-Eomes cells are involved in the maintenance of physiological homeostasis, offering potential avenues for therapeutic interventions for age-associated diseases, conditions characterized by chronic inflammation and to prolong the health span."

https://t.co/73pRZ6o5Ss

[Lifespan News @LifespanNews]

Scientists have discovered that a subtype of immune cells, enriched in older people, helps control cellular senescence. This hints at a new type of anti-senescence strategy but also suggests that an immune system can be “overly youthful.”
https://t.co/4fX6QzIA3s
By: @ArkadyMazin

[Monsonego Lab @MonsonegoLab]

Recently honored to host the UK Ambassador to Israel, Simon Walters (@simonwaltersuk), at our lab at Ben-Gurion University ! 🇮🇱🇬🇧 We had an insightful discussion about the challenges of Alzheimer’s disease. Thank you for supporting scientific cooperation! @bengurionu @ukinisrael

[Monsonego Lab @MonsonegoLab]

@fohsbgu @NatureAging https://t.co/WUxuez6KeH

[Faculty of Health Sciences-BGU @fohsbgu]

A new @NatureAging study from Prof. Alon @MonsonegoLab, identifies a unique CD4 T cell subset that may help protect the aging body and support a healthier immune system.
More: https://t.co/7Bmn1kZUQ3

[Monsonego Lab @MonsonegoLab]

https://t.co/w70mkD1hQ7

[Aging Science News @AgingBiology]

CD4 T cells acquire Eomesodermin to modulate cellular senescence and aging
https://t.co/pTDgyuzMFk

[Nature Aging @NatureAging]

🗞️Our October issue is live!📷This month, we're featuring work on regulators of cognitive decline, senescence – immune interplay, herb-derived geroprotectors and more. Read it all here: https://t.co/baQPAD397c

[TimePie (focus on anti-aging science) @TimePieChina]

New findings demonstrate the fundamental role of CD4-Eomes cells in modulating tissue senescence, with implications for age-related diseases and longevity.
#senescence #longevity #senolytics
https://t.co/usxhwOtQs9

[Organelle Therapeutics @organelletx]

T Cells Fight Aging with Eomes 💥

CD4 T cells express Eomesodermin to regulate senescence and aging offering new hope for immune-based anti-aging therapies

#ImmunoAging #CD4Tcells #Eomesodermin #CellularSenescence #Longevity #AgingResearch
https://t.co/yZ7vNxU2x4

[Monsonego Lab @MonsonegoLab]

We are happy to share our new publication in Nature Aging!

We show that CD4⁺ T cells acquire the transcription factor Eomesodermin to restrain cellular senescence and maintain tissue integrity.

For the full version of the study:
🔗 https://t.co/A0c1xsqbLt