Mostafa I.H. Ali

PhD | Computational Biologist @OhioState
RCC • Immuno-oncology • Single-cell • Machine learning in medical oncology • Spatial technologies at HasanovLab.

[Elshad Hasanov, MD, PhD @HasanovLab]

Proud to see our PhD student, @MostafaIHA, present his work on the single-cell and spatial landscape of RCC brain metastases @OSUCCC_James @OhioStatePIIO @Pelotonia.

Using single-nucleus RNA-seq, spatial transcriptomics, and computational biology, his research explores mechanisms of immune dysfunction and therapeutic resistance in CNS metastases.

Excited to see this work advance our understanding of brain metastasis biology and precision oncology.

#KidneyCancer #BrainMetastases #SingleCell #SpatialTranscriptomics #PrecisionOncology #HasanovLab #OSUCCC #CodeToClinic

[Elshad Hasanov, MD, PhD @HasanovLab]

Excited to share that our team has received @Pelotonia Idea Award to develop AI-powered tools that help personalize treatment for kidney cancer.
By combining spatial biology with artificial intelligence, we aim to predict which treatment are most likely to benefit each patient and bring more precision to cancer care.
As I prepare for my next Pelotonia ride, I’d be grateful for your support. 100% of every dollar raised through Pelotonia goes directly to cancer research.

https://t.co/oitMR6XI15

Together, we can help turn ideas into better treatments for patients.
@eric_facs @EJonasch @UTMDAnderson @bilenma @EmoryUniversity
Dr.Shakya Dr.Niazi @OSUCCC_James
@OhioStatePIIO

#Pelotonia #CancerResearch #KidneyCancer #AI #PrecisionOncology #CodetoClinic #BikeforBrainMetastasis

[Katy Beckermann @katy_beckermann]

@HasanovLab group built RCC-BM, a tool predicting BM outcomes from patient-level parameters. Code to clinic, live!

https://t.co/gGQNKCVpTT

#KCRS26 #KidneyCancer #GUonc
@kidneycan

[Elshad Hasanov, MD, PhD @HasanovLab]

Pilots complete hundreds of hours of flight ✈️ simulation before carrying hundreds of passengers. Why shouldn’t we apply the same philosophy before enrolling hundreds of patients into clinical trials 💊 💉 ?
Excited to share our work on an AI-powered framework, led by #CodetoClinic team @ZuhairMajeed @PengLi_AI @docnurlan that emulates a Phase III trial in #RCC through ML model transfer.
Great discussions with @realrickpazdur @US_FDA and @AACR #AACRdrugdev26 Program Chair @lillian_siu on the future of in silico clinical trials, real-world evidence, and AI-driven drug development.

I believe in silico trials will become a routine step in clinical development, improving trial design before the first patient is enrolled.

#InSilicoTrials #AI #ClinicalTrials #KidneyCancer

@OSUCCC_James @OhioStatePIIO @Pelotonia @OSUWexMed @OhioStateMedOnc @KidneyCancer

[Mostafa I.H. Ali @MostafaIHA]

@ZuhairMajeed @HasanovLab @IKCCorg @OSUCCC_James @OhioStatePIIO Congrats @ZuhairMajeed you deserve the best

[Elshad Hasanov, MD, PhD @HasanovLab]

Congratulations, @ZuhairMajeed! This recognition is very well deserved and reflects your hard work, curiosity, and dedication to improving outcomes for patients with #kidneycancer. #WorldKidneyCancerDay It has been a pleasure to work with you and watch your growth as a physician-scientist. I am grateful to our entire #CodeToClinic team @HasanovLab @OSUCCC_James @Pelotonia @OhioStatePIIO @OhioStateMedOnc @OSUWexMed for their collaborative spirit and commitment to impactful research. Looking forward to seeing all that you accomplish through the @IKCCorg Cecile & Ken Youner Scholars Program and beyond. @IMG_Oncologists

[Mostafa I.H. Ali @MostafaIHA]

Very Grateful to be a part of a big vision and mission at @HasanovLab for kidney cancer .

Additionally, I am so super grateful to be a student at @HasanovLab and being supervised by Dr. Elshad Hasanov, MD, PhD @HasanovLab. Thank you for granting me such opportunity .

[Elshad Hasanov, MD, PhD @HasanovLab]

Proud to see our PhD student, @MostafaIHA, present his work on the single-cell and spatial landscape of RCC brain metastases @OSUCCC_James @OhioStatePIIO @Pelotonia.

Using single-nucleus RNA-seq, spatial transcriptomics, and computational biology, his research explores mechanisms of immune dysfunction and therapeutic resistance in CNS metastases.

Excited to see this work advance our understanding of brain metastasis biology and precision oncology.

#KidneyCancer #BrainMetastases #SingleCell #SpatialTranscriptomics #PrecisionOncology #HasanovLab #OSUCCC #CodeToClinic

[Elshad Hasanov, MD, PhD @HasanovLab]

Congratulations to our star Heme/Onc fellow, @ConquerCancerFd #ASCOMeritAwardee @ShriyaDeshmukh3, presenting at #ASCO26, the spatial transcriptomic profiling of the tumor microenvironment in metastatic RCC treated with sunitinib.

If you missed the presentation: https://t.co/9tGNPj2nkq

We are grateful to our collaborators at @UTMDAnderson, @EJonasch, for leading this IIT and @KidneyCancer, @sitcancer, @OhioStatePIIO for funding correlative studies, @HasanovLab bioinformaticians @MostafaIHA @joseovandor leading analysis.

#ASCO26 #SpatialTranscriptomics #TumorMicroenvironment #PrecisionOncology #MachineLearning #CodeToClinic
@ASCOTECAG @OhioState @OhioStateMedOnc @OSUCCC_James @ASCO @Pelotonia

[Elshad Hasanov, MD, PhD @HasanovLab]

Excited to share our upcoming presentations at #ASCO2026 from the @HasanovLab @OhioStatePIIO and collaborators.
This year, our team will present 12 studies spanning:
https://t.co/jlGQZKe0vq
🤖 AI/ML precision oncology
🧠 RCC brain metastasis biology
🧫 Spatial & single-cell transcriptomics
🌎 Real-world outcomes research with ML models
💻 In silico clinical trial modeling
These projects reflect our 💻 #CodetoClinic 👩‍⚕️👨‍⚕️translational framework, integrating computational oncology, multi-omics, and clinical research to advance precision cancer care.
Grateful to our incredible trainees, collaborators, patients, and mentors who made this work possible. https://t.co/8SlON6F4d0

@OSUCCC_James @ASCOPost @ASCO @KidneyCancer @kidneycan @urotoday @OncoAlert @oncodaily @OncLive

#KidneyCancer #BrainMetastases #PrecisionOncology #AIinOncology #SpatialBiology #SingleCell #TranslationalResearch

[Elshad Hasanov, MD, PhD @HasanovLab]

A perfect holiday-season read with hot chocolate & cookies ☕️🍪❄️ @trendscancer
“Mapping Heterogeneity in the Tumor Microenvironment of Renal Cell Carcinoma Through Single-Cell Omics” Led by our rising star physician-scientist @BetulGokYavuz1 ✨
Free link: https://t.co/r4lnjsnd5I
Grateful for the @trendscancer editorial support, excellent reviewers, and our passionate team & collaborators @OhioStatePIIO @OSUCCC_James @OSUWexMed @KidneyCancer @kidneycan @IKCCorg 🙌

[Elshad Hasanov, MD, PhD @HasanovLab]

Empowering You @KidneyCancer Patient Education Event: Inspiring and comprehensive morning session and panel discussion by @GEVaughan1 @eric_facs @fuatbcr @lingbin_meng @MartyMakary @shawndason @OSUWexMed @OSU_Urology
Tremendous progress in the field, yet many important questions remain bringing us closer to a cure! 🧡🧫🔬💻💊

[Ohio State Medical Oncology @OhioStateMedOnc]

🚴‍♂️ @HasanovLab @AsrarAlahmadi & Tim Burns representing @OhioStateMedOnc at @Pelotonia

[Eric A. Singer, MD, MA, MS, FACS, FASCO @eric_facs]

⁦@KimrynRathmell⁩ delivering the keynote address at #KCRS25. ⁦@OSUWexMed⁩ ⁦@OSUCCC_James⁩ ⁦@OSU_Urology⁩ ⁦@kidneycan⁩

[Elshad Hasanov, MD, PhD @HasanovLab]

Inspiring Keynote speech from @KimrynRathmell at @kidneycan #KCRS25: “The bottom line is we need more people going into science, and open doors to engage the public in partnership.”
@OSUCCC_James @OhioStatePIIO @OhioStateMedOnc @Pelotonia @eric_facs

[Mostafa I.H. Ali @MostafaIHA]

@Sanbomics Happy to see your work in nature @Sanbomics . Great Job !

[Jun Kim @Jun_kiim]

Combination of surgical upfront immunotherapy with aglatimagene besadenovec (CAN-2409), followed by chemoradiation and then adjuvant nivolumab for newly diagnosed glioblastoma (Wen et al. March 2025, @NeuroOnc).

@EAChiocca & @paulpetertak

[Mostafa I.H. Ali @MostafaIHA]

@AhmedMKamel2000 Thanks

[Mostafa I.H. Ali @MostafaIHA]

Sometimes Dream become TRUE, I wanna share that My Journey has started in the USA 🇺🇸, I want to thank all of my supervisors, mentors, friends who helped me to reach it out.

#buckeye

[Mostafa I.H. Ali @MostafaIHA]

@AmerLabOSU Congrats, Dr.

[Mostafa I.H. Ali @MostafaIHA]

I was super excited to talk about the tumours heterogeneity in human cancers and its effect on the chemotherapy resistance, cancer development and progression @Egypt.