Emilio Mottillo

Husband, father, Assistant Scientist at Henry Ford Hospital interested in metabolic research. Tweets are my own.

[Emilio Mottillo @Mottillo_Lab]

We have the lab up and running! Looking to recruit a post-doc to join us in the “D”. Applicants interested in metabolic disease research with an inkling towards using imaging approaches to study lipid metabolism. https://t.co/tY0PWMHAyC DM @Mottillo_Lab Please RT. Thanks!

[Daniel J Drucker @DanielJDrucker]

The tragic transition of 🇨🇦 from fighting alongside 🇺🇸 in 2 world wars and in Afghanistan, rescuing American hostages in Iran, working collaboratively with our American neighbours across a spectrum of endeavours, now waking up with sadness to a new economic declaration of war 💔

[Emilio Mottillo @Mottillo_Lab]

Finally, LD targeting of PNPLA3 I148M is required to promote steatosis in vivo. Overall, data suggest a critical role for PNPLA3 I148M - LD localization to sequester ABHD5 and promote steatosis.

[Emilio Mottillo @Mottillo_Lab]

Our JBC paper is now online! Here we examine the mechanisms by which a common genetic variant in PNPLA3 (148M) causes fatty liver disease and builds upon our previous work on the interaction of PNPLA3 with ABHD5.
https://t.co/mI3tf1J6hY

[Emilio Mottillo @Mottillo_Lab]

Targeting of ABHD5 to LDs is also required to promote the interaction with PNPLA3. So both proteins need to be on LD!

[Emilio Mottillo @Mottillo_Lab]

New study from @Z_GerhartHines lab identifying a novel pathway regulating food intake and energy expenditure
https://t.co/VddnyjDVE6

[Emilio Mottillo @Mottillo_Lab]

@AlicePollard91 @MRC_LMS @BBSRC @imperialcollege @DiabetesUK @ESEndocrinology @stsforum Congrats Alice!

[Emilio Mottillo @Mottillo_Lab]

@nobletalari Thank you!

[Emilio Mottillo @Mottillo_Lab]

Had a great time in Munich at the Helmholtz Diabetes conference. It was an honor to be nominated for the HeIDi Young Investigator award and present our work. Wonderful meeting all the new people and connecting again with colleagues!
https://t.co/IXo0MM6uSf

[Emilio Mottillo @Mottillo_Lab]

@HelmholtzMunich Congrats to the HeIDi winners! It was a wonderful conference.

[Helmholtz Diabetes Center (HDC) @helmholtz_diabc]

Let the games begin! 🎉

The 11th Helmholtz Diabetes Conference has officially begun! Stephan Herzig just opened the event, and we’re very excited for the next 3 days full of cutting-edge research focusing on wasting metabolism! 🙌

#HelmholtzDiabetes2024

[Emilio Mottillo @Mottillo_Lab]

@OlzmannLab @UCBerkeley @DanNomura @RobertoZoncu @RapeLab @SJD956 Congrats James, well deserved!

[Emilio Mottillo @Mottillo_Lab]

@Shahnaz_Physics @CellRepMethods Congrats everyone! @C_V_Kelly @CVKellyLab

[Emilio Mottillo @Mottillo_Lab]

@Immunometabolab Congrats Morgan! Well deserved!

[Emilio Mottillo @Mottillo_Lab]

Our paper is now online! Here we investigate the direct effect of lipolysis on AMPK signaling in adipocytes. Using our real-time FRET sensor we show lipolysis genereates long-chain acyl-CoAs that are involved in allosteric activation of AMPK.#lipidtime
https://t.co/ozdqOHRWNw

[Emilio Mottillo @Mottillo_Lab]

New work from S. O'Rahilly's group shows GDF15 drives nausea and vomiting duirng pregnancy. Interesting study! https://t.co/yIMMg3RvOA

[Emilio Mottillo @Mottillo_Lab]

@micahschott @waynestate Thanks Micah!

[Emilio Mottillo @Mottillo_Lab]

Happy to share my promotion to Associate Professor of Physiology at Wayne State University @waynestate

[WSU-Physiology @GradPhysiology]

Congrats to Dr. Emilio Mottillo who was recently notified he has been promoted to Associate Professor (Research) FTA in Physiology effective August 2024!

[Emilio Mottillo @Mottillo_Lab]

@amtya21 @waynestate Thanks Amit

[Emilio Mottillo @Mottillo_Lab]

@Kei__Sakamoto @waynestate Thanks Kei!