Bladder Preservation Strategies in Muscle-Invasive Bladder Cancer in @JCO_ASCO
➡️TMT achieves survival comparable to radical cystectomy in selected pts, with better QoL
➡️Immunotherapy +/- ChT/ADC +/- ctDNA/utDNA are redefining who can safely avoid surgery
The future is bright 🌟🤩
https://t.co/OhRfH4Hwpd @OncoAlert
Treatment of #UTUC with UGN-101: Baseline characteristics from the uTRACT Registry study for UGN-101. Presentation by Marc Bjurlin, DO, MSc, FACOS @UNC. #SESAUA26 written coverage by @zklaassen_md@GACancerCenter > https://t.co/00uU7g4yY6 @SES_AUA
Pleased to share our study published in @CCR_AACR 👉 https://t.co/KaWP3XNefM
📍NF2 loss (merlin deficiency) in RCC delineates a distinctly aggressive biological phenotype:
⏫ heightened proliferative capacity, profound immune dysregulation, and recurrent alterations in cell cycle and DNA damage–response pathways.
⏬ limited efficacy of immunotherapy further underscores the pressing need for biomarker-driven, molecularly tailored therapeutic strategies.
#Oncology #cancer #kidneycancer
@DrChoueiri@MikeSerzanMD@WeiweiBian@OncoAlert@DanaFarberNews@DanaFarber_GU@AnkaraUni
Kidney cancer care just got a major upgrade.
The NICE 2026 guideline finally gives a full roadmap for RCC, from diagnosis → treatment → follow-up.
⚙️ What changes in clinic:
🔬 Biopsy matters more
• Recommended for small renal masses (≤4 cm) when it impacts decisions
👀 Active surveillance is legit
• Now standard option for selected small tumors + Bosniak 3 cysts
🔪 Surgery still leads
• Remains gold standard for many localized cases
🔥 Non-surgical options
• Ablation / SABR for patients unfit or unwilling for surgery
📊 Follow-up gets smarter
• Risk-adapted imaging instead of one-size-fits-all
👨⚕️ Team-based care
• Strong push for MDT + clinical nurse specialist access
💡 Takeaway
👉 Less overtreatment, more personalization, better structured RCC care
🔖 This will change real-world practice more than most trials.
📖 Full paper in comment ⬇️
#OncoTwitter #MedTwitter #KidneyCancer #RCC
@OncoAlert@myesmo@esmo_open@asco
You may have seen this photo of an elderly woman captured by terrorists on October 7th.
At 85 years of age she is the oldest Israeli hostage who was abducted by Hamas.
Her name is Yaffa Adar and this is her story.
🧵1/25
Today in Montreal Jewish father with 3 kids beaten in an unprovoked attack, seemingly by a disturbed person, words have consequences. @Val_Plante@SPVM why did it take for the SPVM over an hour to respond?
The most interesting finding from the IDF report on the October 7 attack on Kibbutz Be’eri is that only 100 of the 340 terrorists who entered that kibbutz were Hamas. 240 of the 340 were Palestinian civilians. 70% of the Palestinians who attacked the kibbutz were civilians.
This holds across the board. Palestinian civilians made up the majority of the terrorists who attacked Israel on October 7.
500 days ago, Palestinian civilians entered the ravaged village of Kibbutz Nir Oz to search for loot.
Inside a locked safe room, they found a terrified mother, a 3 year old toddler, and a 9 month old baby.
They used power tools to break down the door to the safe room, and dragged out the family.
They filmed and tormented the mother while she desperately clutched her babies in her arms.
Then they kidnapped the Bibas family into Gaza where they sold them to the highest bidding jihadist group in a modern day slave trade.
For 500 days Jews across the world have been praying for a miracle while living a nightmare most Jews have not experienced since the Holocaust.
We screamed their names, put up posters of their images, begged the Red Cross to provide them medical care, and pleaded for their release.
Our cries were ignored, our posters were torn down, and “human rights groups” across the world refused to help even a helpless 9 month old baby.
Tomorrow, on day 502, in an undisclosed location, HMS will deliver the bodies of Shiri Bibas, Ariel Bibas, and Kfir Bibas.
They will film and torment the Jewish people by desecrating their bodies in some macabre terror show broadcast by Al Jazeera.
They will spin and twist and manipulate the truth.
All to cover up the fact that 500 days ago, Palestinian civilians entered the ravaged village of Kibbutz Nir Oz to steal the most important treasure to the Jewish people—A loving mother and her two innocent babies, a symbol of all our hopes and dreams for the future of the Jewish people—and murdered them in captivity.
BDE 😔
3 generations of one Jewish family wiped out by Gazans purely for the sole reason that they were Jews.
This is what the intentions of a Holocaust look like.
That’s what Gazans wanted when they planned and celebrated October 7th.
They are the genocidal ones. Never forget.
Meet Oded.
A journalist for a far-left Israeli socialist newspaper, Oded was a fluent Arabic speaker and vociferous advocate for Gazan rights.
So much so that he volunteered for a decade with "Road to Recovery" to personally transport children from Gaza (where there were 36 hospitals) to Israel for the best medical care.
Tomorrow, he's coming home from Gaza in a body bag, betrayed and murdered by the very people he fought so ardently for.
May his memory be a blessing. And a lesson.
Israel confirms that the Shiri Bibas and her two baby boys Ariel and Kfir were murdered in Palestinian captivity. Their bodies will be returned tomorrow from Gaza in exchange for Israel releasing Palestinian criminals.
Every emotion you feel — I feel that and then some.
⚠️ GRAPHIC FOOTAGE
Unfortunately, some people on this platform still need a reminder of what happened on October 7th.
Millions of Israelis don’t need the reminder—we are living through it every single day.
We will never stop speaking up—for the living, for the dead, for the hostages.
Share this.
אנחנו נלחמים יום יום באירוע הזה, הצלחנו להביא להשעייה לצמיתות של חלק מההתארגנות למחיקת העם היהודי, ההיסטוריה שלו ומדינת ישראל.
אני מבקשת מכם -
עזרו לנו בעוקב
עזרו לנו בשיתופים
אחד התחקירים שלנו הגיע ל-100 מיליון צפיות ברשתות והוביל לחקירה והשעייה של התארגנויות זדוניות בוויקיפדיה.
אנחנו עושים שינוי באתר שיש בו מיליארדי ביקורים מדי חודש, שהוא התוצאה הראשונה בגוגל לכל כך הרבה מילות חיפוש, שהוא פקטור בתשובות שאתם מקבלים במנועי הבינה המלאכותית.
עזרו לנו עם עוקב, לייקים ושיתופים להשפיע יותר והצטרפו לקהילות שלנו (קישור בתגובה הראשונה, 1-2 דקות ביום).
תודה
The story of Sophia Khalifa, a Muslim Arab living in Israel as an Israeli is one of the most powerful and beautiful stories that absolutely everybody should watch and hear.
The leftists and Islamists would never want anyone watching it