Nicholas Forelli

Aspiring physician-scientist, Resident Physician at The University of Pennsylvania. Member of the Arany Lab #Einsteinmed alum

[Chaz Hong MD PhD 🇺🇸 @chaz_hong]

It's almost as if NIH has been taken over by rouge ideologues. Drastic cuts in indirects are like cutting off your nose to spite the face. For mere $4B in "savings," this will end the dominance of American research universities, the best damn value for American tax payers. And when did doing life-saving medical research & providing care to the neediest make you a dinosaur?

[Sarah Abramowitz @sabramowitz_]

Now out in @JAMA_current: How well do individual risk estimates from different CHD polygenic scores agree? Grateful to work on this with a dream team of mentors and co-authors @damrauer @MGLevin @bpasaniuc @MarylynRitchie @dokyoon_kim @bvoight28 @BoulierKristin @karlkeat

[PennCVI @PennCVI]

CVI's Highlighted #PapersoftheWeek
@AranyLab
https://t.co/rPIhR6zE27

[Pradeep Natarajan @pnatarajanmd]

Are you an MD student interested in research?
Would strongly consider applying for the @SarnoffCardio Fellowship. Scientific immersion with *unparalleled* longitudinal mentorship & exceptional peer network career-long. https://t.co/v8Hz9bxwYC
My biggest regret in med school was not participating despite guidance from mentors. Now I'm thrilled to join this vibrant community on the Scientific Committee.
Nice summary of the program https://t.co/GE79jX8RUW @CircAHA
Track record of successful physician-scientists going through this program is impressive - the recipe of immersion + longitudinal engagement/sponsorship/mentorship works very well

[Nicholas Forelli @NicholasForelli]

@tweetineaton @AranyLab Could not have done it without you, Deb!

[Nicholas Forelli @NicholasForelli]

Our Story is Out - on BioRxiv! Humbled to have worked with such a great team of scientists to investigating how #SGLT2 inhibitors provoke their astounding cardiac benefits.

[The Arany lab @AranyLab]

We think this one is groundbreaking: Do you wonder how #SGLT2 inhibitors protect from heart failure? We show that #empagliflozen directly activates PANK1, rate-limiting for CoA synthesis, in human hearts. You read it here first! https://t.co/EAaKaI104X

[Nicholas Forelli @NicholasForelli]

@chaz_hong @EinsteinMed @zoltarany @PennCVI @SarnoffCardio Thank you @chaz_hong its all the great mentorship from @SarnoffCardio !

[Destiney Kirby, MD, MPH (she/they) @DestineyKirby]

Destiney Kirby, MPH today💃🏽 Looking forward to adding the MD next year!

[The Arany lab @AranyLab]

So proud !! congratulations Megan and Quentin -- newest Aranylab graduates. Watch out world, here they come! @MeganCBlair @CAMBUpenn

[Greg Lewis @GLewisCardiol]

Very proud of @CampainJoseph, outstanding Sarnoff Fellow in my lab this year from UTSW @josephahill who just presented his work on O2 kinetics in HFpEF compared to a community cohort at the 43rd Annual Sarnoff Scientific Meeting . @Raj_MalhotraMD @MGHHeartHeath @MGHMedicine

[Nature Medicine @NatureMedicine]

11 clinical trials that will shape medicine in 2023.

Part of our Year in Review, written by @edbites and Paul Webster

https://t.co/xe2jO35kDf

[Lena E. Trager, MD @LenaETrager]

What happens to non-cardiomyocytes in the heart with aerobic exercise? Check out our new review paper in @JSHS_MedHealth from the @rosenzweig_a lab @lihaobo @JSawallaGusehMD @sashalkuznet

[Bryan Carmody @jbcarmody]

I don’t usually brag about our residency program, but today I’m gonna make an exception.

Like other children’s hospitals, we’re managing a surge in respiratory illness.

But unlike most hospitals, we’re gonna pay the residents who work extra overnight/weekend shifts $100/hour.

[Sarnoff Foundation @SarnoffCardio]

Current Sarnoff Fellows and Scholars at the AHA Scientific Sessions!

[Nicholas Forelli @NicholasForelli]

Phenomenal talks on #HFpEF here at #AHA22

[The Arany lab @AranyLab]

Oops wrong link for Danielle - apologies ! @Yoshiko96821

[Nicholas Forelli @NicholasForelli]

Barry Sharpless with his second Nobel in chemistry!

[The Nobel Prize @NobelPrize]

BREAKING NEWS:
The Royal Swedish Academy of Sciences has decided to award the 2022 #NobelPrize in Chemistry to Carolyn R. Bertozzi, Morten Meldal and K. Barry Sharpless “for the development of click chemistry and bioorthogonal chemistry.”

[Vincent Libis @VincentLibis]

Interested in heterologous expression of large numbers of biosynthetic gene clusters?

My focus over the past years has been to try to make this process more scalable.

Have a look at this new approach, I used it to discover a new antibiotic: conkatamycin
https://t.co/leqPOQZb4n

[Chaz Hong MD PhD 🇺🇸 @chaz_hong]

Modeling Heart Failure with Preserved Ejection Fracion (HFpEF) in Rodents: Where do we stand?
>3 million in US suffer from it. Accurate preclinical models are critical to develop new drugs. This review by @MTChinMDPhD sets the framework. @FrontDrugDDS
https://t.co/UlptHbdYsz

[Ananya Sharma, MD @AnanyaSharms]

It’s a special kind of joy when you see your cardiomyocytes beating for the first time 🥰 #SarnoffYear #CardioTwitter #WomenInSTEM