Nirav Florian Chhabra

Postdoctoral researcher (Metabolism | Pancreatic cancer | scRNA-seq) @TU_muenchen

[Nirav Florian Chhabra @NiravFC]

📢Finally out in @CellRepMethods! We developed DCTC — an isolation protocol for live cells from murine pancreas
✅No fixation or dead cell removal
✅80-90% acinar cells
⚡️Uncovered acinar cell heterogeneity & ADM dynamics
⭐️scRNA-seq | fow cytometry
📄https://t.co/LWAEqzsQIL

[Katrin Böttcher @KBoettcherLab]

📣 !! JOB ALERT for PhD students !!

My lab is moving to the M3 Research Center at the University of Tübingen and is looking for PhD students who are enthusiastic about translational research.
If you are, read on below ⬇️

[Nirav Florian Chhabra @NiravFC]

📢#Metabolic reprogramming in early stage of #PancreaticCancer can be targeted to Inhibit #ADM
@alice_mc_chen @yhnb4f4yqb
https://t.co/ZoW1lPBXz6

[Nirav Florian Chhabra @NiravFC]

@AmendAnnalena @Dr_Meming Absolutely…! 😅

[Nirav Florian Chhabra @NiravFC]

@AmendAnnalena @arispapargyriou Most def!

[Nirav Florian Chhabra @NiravFC]

#Metabolic programming is essential for the initiation of #pancreatic #carcinogenesis and thus identifies potential targets for metabolic intervention
Out now - preprint from our lab @sfb1321 https://t.co/XDeXpi8HSL

[Nirav Florian Chhabra @NiravFC]

Excellent point. Even if these are backed by good intentions (which is doubtful), the execution of it will bring only minor changes to the numbers but certainly hamper scientific research on a large scale.#AcademicTwitter

[Kıvanç Görgülü @kivancgorgulu]

This situation will decelerate some research fields.These rules should be shaped internationally.Otherwise, it's just racing under inequal conditions. 1/5
Germany weighs whether culling excess lab animals is a crime @ScienceMagazine #AcademicTwitter https://t.co/AJUT2Qf0pE

[Nirav Florian Chhabra @NiravFC]

@AmendAnnalena The good old Helmholtz days

[Nirav Florian Chhabra @NiravFC]

@CaATiER_Chop_ER @AmendAnnalena Absolutely!

[Nirav Florian Chhabra @NiravFC]

@CaATiER_Chop_ER @AmendAnnalena Thanks Jing. The key might be “sustained” ER stress - needs further investigation. However, in Pdia6 model, insulin is down at P21 concomitantly with only modest increase in ER stress, suggesting alternative, perhaps indirect action of Pdia6 on insulin transcripts.

[Nirav Florian Chhabra @NiravFC]

@bakhti_mostafa @AmendAnnalena 🙏🏼 thanks a lot!

[Anna-Lena Amend @AmendAnnalena]

Happy to share the journal pre-proof of @NiravFC and my study on the effects of a point mutation in the Pdia6 gene on beta-cell identity and resulting diabetes. We are excited to release this into the beta cell community 🤗🥳 @MolMetab

https://t.co/RiNu1IFTib

[Nirav Florian Chhabra @NiravFC]

@AmendAnnalena @Prokaryota A tiny bit of lawful, a lot of neutral evil!

[Papersums @papersums]

Check out the summary of @Nanatsusaya2's latest publication compressed into a 2min read on https://t.co/v6nWJcMNNL #ScienceMatters

[Nirav Florian Chhabra @NiravFC]

🙏🏼

[Deutsches Zentrum für Diabetesforschung (DZD) @DiabResearch]

Nirav Chhabra et al. @DiabResearch + @HelmholtzMunich found that a Pax6 point mutation identified in a patient with foveal hypoplasia alters circadian rhythms and B cell function without affecting glucose tolerance in mice. #diabetes ➡️https://t.co/SgHVB7O7jU

[Nirav Florian Chhabra @NiravFC]

Excited to present a comprehensive study of a #Pax6 mutation in the context of #energymetabolism and #circadianrhythm published in @CommsBio. A big thanks to everyone involved🙏@helmholtz_diabc @AmendAnnalena @Jan_Rozman @epi_tep @JohBeckers
https://t.co/qupW0SOLxj