Nithya Balasundaram

Post doc #deDuve #UCLouvain #Immunometabolism and #Haematology
Ph.D @offcmcvellore.

[FrezzaLab @FrezzaLab]

As a follow-up to the previous article on "how to ask a good question", here is one on the infamous "Burden of Knowledge". I'd love to hear your views on this.

Thinking like a Scientist, Part five: The Burden of Knowledge https://t.co/9QWPtwjC0M #FEBSnet

[Nick van Gastel @nickvangastel]

New preprint from the lab! In this study we dive into the mechanisms that give #leukemia cells #metabolic plasticity, and how it differs from healthy cells. We discovered a process involving rapid changes in protein S-acylation unique to leukemia!
https://t.co/8fSHghghJA

[Nick van Gastel @nickvangastel]

New preprint from our lab! Given the importance of nucleotide synthesis for AML cells, and the fact that aspartate is essential for nucleotide synthesis, we wondered if exogenous aspartate uptake through EAAT transporters plays a role in this cancer.

[ISEH @ISEHSociety]

Take advantage of the opportunity to speak at the Mini Symposium by submitting an abstract by 26 February. Learn how and register today ➡️ https://t.co/3cSp43Oj5X

[ISEH @ISEHSociety]

Check out the latest #SimplyBlood🩸 post highlighting two Experimental Hematology Young Investigator articles from 2023, which both explore important biological questions in normal and malignant hematopoiesis using murine models. ➡️ https://t.co/2NCQisaloN

[FrezzaLab @FrezzaLab]

When my lab members started to leave, I felt like a failure as a mentor | Science | AAAS https://t.co/mdMBDGL1FU

[Waggoner Lab @LabWaggoner]

Manganese boosts NK cell function via cGAS-STING mediated UTX expression
https://t.co/63DXANGuRX

[Nick van Gastel @nickvangastel]

Two posters from our lab at #ISEH2024 today: @hernan_tiradoc presents his work on GOT enzymes as metabolic vulnerability in AML (nr 3234), and I present work from @Nithya029 and @Aysglrdm on how protein S-acylation allows metabolic flexibility in AML (nr 3004)! @ISEHSociety

[Nick van Gastel @nickvangastel]

I'm very excited to share the first original research paper of the lab, out now in Experimental Hematology! @ISEHSociety @deDuveInstitute @UCLouvain_be @WELRI_asbl
Optimization of pre-enrichment strategies for mouse hematopoietic stem... https://t.co/Xgs5ACYgYa

[Waggoner Lab @LabWaggoner]

Inhibition of a mutated metabolic enzyme puts the sting back in antitumor immunity
News @ScienceMagazine @PitarresiLab @FitzgeraldKate
https://t.co/f5gyoKoyRv
@MJWu_TW @MangusoLab
https://t.co/qdExCs7Oa9

[Alejo Rodriguez-Fraticelli @AlejoFraticelli]

2021 rejection: “it will never work”
2022 rejection: “it will never work”
2023 rejection: “it will never work”
2024 rejection: “this has already been shown”

😂 https://t.co/TyELd6Tgl3

[Waggoner Lab @LabWaggoner]

Combining clinically relevant STING agonists with BH3-mimetic drugs efficiently kills TRP53/TP53-mutant mouse B lymphoma, human NK/T lymphoma, and acute myeloid leukemia cells @Cancer_Cell
https://t.co/HOGIURRjYF

[Keisuke_Ito_Lab (Old) @The_Ito_Lab]

Super-excited to share our latest work @CellStemCell, unraveling the mitochondrial NADPH-cholesterol axis for EV biogenesis, guiding precise HSC fate! Huge congrats to Massimo @MassimoBONORA1, Claudia @Cla_Morganti, and Nick @nickvangastel! @Einstein_SCI https://t.co/xTC8uJvW38

[Waggoner Lab @LabWaggoner]

"..if you leave a meeting with a mentor feeling like your possibilities have narrowed rather than broadened, you know you’ve got the wrong mentor."
https://t.co/a5qKfxfd9V

[Science Magazine @ScienceMagazine]

"I am discovering that my traits are valuable."

In this week's #ScienceWorkingLife, researcher @CGoeyers writes about how she, amid her #PhD struggles, learned she is neurodivergent—and found ways to thrive. https://t.co/yzq056d6Yo

[Nithya Balasundaram @Nithya029]

@sars_ganesan @ASH_hematology @landau_lab @AbdelWahablab Congrats .. @sars_ganesan 😃

[Science Magazine @ScienceMagazine]

"We sometimes draw a false equivalence between research advisers and mentors. And while many advisers are excellent mentors, it’s not exactly a prerequisite for running a lab. But it doesn’t have to be that way." #NationalMentoringMonth https://t.co/PieZbawuZc @ScienceCareers

[Nature Biotechnology @NatureBiotech]

It takes two to think - @ItaiYanai & @MartinJLercher https://t.co/UqubzsV8nx

[Sdelci Lab @SdelciL]

ARE METABOLIC ENZYMES ON CHROMATIN?
Yes, they are ⤵️!
We optimized a chromatin enrichment protocol to improve the extraction of chromatin-bound proteins (chromatome) and applied it to > 140 samples, including cancer cell lines and healthy epithelia from 10 different tissues. 🧵

[Nature Metabolism @NatMetabolism]

Online now! A century of the Warburg effect https://t.co/Mrhxzn2IT9