#DeSci is in nascent with raw experiments, #Octan is very early too, but massive potential. We are now staying focused on RnD. Please stay tuned https://t.co/qyoDxzQ4u2
1/2. #Sybil detection is a big challenge in #Web3, costing huge budgets & efforts of Arbitrum, OP, Layerzero to classify eligible wallets. Octan gives a scalable, cheap solution based on machine learning, achieving high accuracy https://t.co/ZzQhax54hU
2/2. the blog is written by #Octan's principal scientist @scottonchain, addressing onchain Sybil detection using XGBoost. This problem is requested by @BNBCHAIN in its latest hackathon. #DeSci = onchain Data Science @cz_binance
DeSci adopted by traditions. Nature — one of the world’s most cited scientific journals in the world — has just featured ResearchHub, a decentralized science (DeSci) protocol, noticing the wider scientific community to #DeSci & cryptos. https://t.co/XZZLmcwaAR
Here are some insights that stood out to me recently:
I’m speaking with other VCs daily, including some of the biggest and most reputable firms in the space.
While market hype shifts quickly from one narrative to the next, smart money and major institutions obviously are monitoring the market way deeper, with a longer-term focus and a broader perspective.
What stands out is that the overlap among the vast majority of these players is concentrated on three key verticals:
DePIN
DeSci
DeAI
Of course, there are other promising verticals that some big investors are also bullish on. However, I found it striking how these three resonate with the absolute majority.
By now, it seems pretty obvious that, compared to others, these areas are not just trends - they’re here to stay forever.
Come with us in the biggest DePin event at Vietnam Tech Summit - Vtis. Onchain Data Science & Data Intelligence are the foundation of Data-driven business, also the best utilization of #DePINs#DeSci
1/ 💳 @Wal8io
Transform everyday purchases into a gateway to Web3.
Data ownership: Consumers own, control, and earn from their data.
Seamless integration: Works with all digital payments—no app download required.
2/ 🌐 @Functionland
Building the decentralized backbone for AI development.
User-owned ecosystems: From distributed storage to GPU resources.
Cost-efficient: Custom hardware + mobile-native apps reduce AI costs while ensuring data sovereignty.
3/ ⚡ @Digitalabs_AI
Next-gen decentralized cloud for AI, gaming, and HPC.
Pay-as-you-go: Flexible access to GPU/CPU clusters.
Scalable power: Perfect for businesses scaling AI models or gaming workloads.
4/ 🕊️ RoRo Birds
A fun, bird-themed multiplayer PvP game with real token rewards.
Web2 & Web3 ready: Easy onboarding for all players.
Skill-based rewards: Combine nostalgia with modern blockchain incentives.
5/ 📊 @OctanNetwork
Unlock data intelligence with on-chain reputation rankings.
Proven innovation: 3 years of R&D behind Sybil-resistant algorithms.
DeSci-powered: Collaborative AI/ML for data-driven breakthroughs.
Pump Science, the DeSci launch platform on Solana, issued a warning that the private key of its wallet T5j2U...jb8sc for creating URO and RIF tokens has been leaked because the developer left the private key of the wallet in the code base. The attacker used the address to generate new tokens. All tokens created through this wallet are considered fraudulent projects. https://t.co/OIVH3sgytK
1/ 🧬 DeSci – (How) Will It Make Research Great Again?
Science is losing its relevance.
🔹But #DeSci is here to change that.
At @OnchainHQ, we analyzed 60+ DeSci projects and uncovered how DeSci reshapes various industries.
Dive in into the decentralized future of research👇
Octan is the next alpha of #DeSci, building onchain data science and data intelligence, established by a novel onchain reputation ranking system, making Pagerank (a trillion-dollar algorithm) great in #Web3
For what it’s worth, I went through this tweet’s 300 comments to filter out the biggest DeSci alpha for you guys.
Here are the Top10 DeSci coins that seem to get a lot of mindshare:
1) $LAKE - @DataLakeToken
2) $RSC - @ResearchHub
3) $GENOME - @GenomesDAO
4) $AXGT - @AxonDAO
5) $VITA - @vitadao
6) $TRAC - @origin_trail
7) $MET - @metforminsol
8) $RIF - @pumpdotscience
9) $GLP1 - @GLP1science
10) $CRYO - @cryodao
Interesting results, I am a big fan of LAKE, RSC and CRYO myself.
GLP1 is super interesting too and is getting a lot of traction since @Rewkang mentioned it.
Gonna deep dive into some of the others, if you have further suggestions, leave some comments!
1/2. PageRank is a trillion-dollar algorithm. Onchain Data Science is HUGE. Octan is combining the two to build a decentralized reputation ranking system onchain powered by adaptive Pagerank with anonymity. True #Desci
The DeSci space right now feels like the early 2019 DeFi days. Everything is still raw, experimental, but there's an underlying understanding from this involved that there is massive potential.
It's likely that the current projects won't have the same model/product as they will in the future but that's because they are developing through iteration. It was this way with Maker, Synthetix, and Aave in 2019 which were clunky microcaps that are now massive protocols
Have found these to be the most interesting
@bioprotocol@pumpdotscience
@GLP1science
Shill me more
@Rewkang Octan is leading data science in Web3, fistly with onchain reputation ranking system to build anonymous trust & credibility, and prevent Sybils
Make #DeSci great. Octan is leading onchain data science with a native Web3 reputation & Sybil detection onchain to establish trustworthiness & credibility onchain without compromising anonymity philosophy of blockchain (i.e NO need of proof of personhood)
At last week’s DeSci Day at the Binance Labs BUIDLer House in Bangkok, we brought together a like-minded community of about 50 biotech and DeSci enthusiasts to exchange ideas and network.
During the 3-hour session, speakers shared insights on topics ranging from the evolution of biotech to Rapamycin and longevity, citizen science, bioDAOs, on-chain IPs, AI agents for science, and more.
Notable bioDAOs shared exciting updates–VitaDAO launched their first longevity supplement, approved by the Thai FDA. HairDAO is expanding with a new wet lab, patenting their second idea, and launching a shampoo with impressive results for hair loss.
We also invited CZ and Vitalik to interact with the community through an open Q&A session and network with other DeSci founders and builders.
Read more in the thread below 🧵
@BinanceLabs#octan is leading onchain data science with a native Web3 reputation & Sybil detection onchain to establish trustworthiness & credibility onchain without compromising anonymity philosophy of blockchain (i.e NO need of proof of personhood)
🔵 𝗢𝗡𝗖𝗛𝗔𝗜𝗡 𝗗𝗔𝗜𝗟𝗬 🔵
Onchain science has the potential to revolutionize the industry, making it more open and accessible than ever before
Mint the short film by @ResearchHub, a platform accelerating scientific funding, research and publishing
https://t.co/P2gYiSVdFk