We were keep getting more and more requests for proteomics analysis for big batch of samples so we managed to install timsTOF pro 2 at our core facility and now we are ready for more MS analysis.
Check out our study with @CBJacksonLab &Battersby lab demonstrating the requirement of supernumerary proteins of the human #mitochondrial#ribosome in mitochondrial protein synthesis and the unique role for mS37. @StGeorgesUni @SGUL_Genetics @helsinkiuni https://t.co/FfNCely1hV
How can you predict kinase activity in phosphoproteomic data? This database allows you to do this, even for poorly annotated kinases. Read more in this new paper: https://t.co/93O0Wnlcyu”
Leutert et al. provide an overview of the basic modes of #PTM crosstalk, the proteomic methods to elucidate PTM crosstalk, and approaches that can inform about the functional consequences of #PTMcrosstalk ― @UW@MarioLeutert@juditvr@sam_entwisle
https://t.co/QViAxfOsal
Very happy to see that our review on "Progress and challenges in mass spectrometry-based analysis of antibody repertoires" is out in @TrendsinBiotech.
https://t.co/4l8pYAXFXr. Led by @ISnapkov@mchernigovskaia @ATGTAC @KhangLeQuy and in collab with @PCFOUSOslo (Tuula Nyman).
What’s the best data-independent acquisition (DIA) workflow for your proteomics experiments? Researchers tested a standard human proteins mixture with 36 workflows including 4 different DIA windows and 6 different software tools to find out.
https://t.co/XzFBz4LOFk
Announcing the release of #FragPipe 15. Improvements in all modules, including MSFragger and IonQuant. Support for TMT, SILAC, LFQ-MBR quant, FAIMS, open PTM searches, glycoproteomics, HLA/peptidomics, spectral library building for DIA analysis, and more. https://t.co/H4Tx88SheU
It has been amazing week! PCF prepared more than 400 proteomics samples in week. We have developed high throughput sample preparations pipeline. If you want to investigate outcome of your drug or gene editing screen at protein level. We can help you with that. @sachinPCFOUS
Very productive day, installation process is much more faster than expected. Most difficult part was decide this amazing things a name. Finally, we named it Hilton II ( in-house name)@napi_norway@sachinPCFOUS@jrbrtsn
Laser capture microdissection combined with quantitative MS-based #proteomics of #celiac intestinal epithelium reveals low-level inflammation in patients that respond strongly to gluten🌾🍞 https://t.co/lqHSDf0dgp @JCoDiRC @PCFOUSOslo
We developed a scalable, quantitative and ultra-high sensitivity workflow for true single cell proteome analysis - one by one. Single cells have a stable proteome but not transcriptome. Great collaboration with @Bruker@EvosepBio@fabian_theis. Preprint: https://t.co/2edZ99u7Xw
"The BOOST strategy can potentially be applied in analyses of other PTMs here treatments that broadly elevate the levels of those modifications across the #proteome are available."
Paper in Press: " TMT PV BOOST channel expands pTyr quantitation depth"
https://t.co/EAg3n07KFS