Crypt hyperplasia in the intestinal lining is a hallmark of celiac disease, but a unified pathological model has not yet been established.
Ludvig M. Sollid @stamnaes & team perform spatial proteomics on patient biopsy samples and experiments in mice, offering a new driver for crypt hyperplasia in #CeliacDisease—interferon-γ: https://t.co/kidd5qaY3T
The figure: IFN-γ induces remodeling including proliferation of crypt cells (Ki67-labeled purple) in mice.
Biopsy proteome scoring can serve as an effective measure of gut disease state following oral gluten challenge in celiac disease: https://t.co/qEOD8wW7HH
@stamnaes
Nesten 50 år, to ERC-stipender, men ikke fast forskerstilling. Er det lov? Ja, faktisk. Møt tre etablerte faste, midlertidige forskere.
https://t.co/fufgmO1Dcb
Great first day of the 1st Norwegian Symposium on Proteomics and Biological Mass Spectrometry! Diverse and interesting talks - looking forward to more tomorrow. Thanks to @forskningsradet, @BrukerMassSpec and @SCIEXOmics for sponsorship.
Happy to share this story on anti-gluten antibodies in celiac disease. https://t.co/dyOCGam3bA The project was led by Chunyan Zhou @JCoDiRC @UniOslo_MED and is the result of a long-standing collaboration with the Buus lab @uni_copenhagen. Main findings are summarized below.
What we can and cannot learn from "omics" analysis of intestinal biopsies in #celiac disease: an approachable dive into the dynamics and complexity of the small intestine: https://t.co/AL3c3dxnXK @JCoDiRC
PhD students at the Centre for Bioinformatics, UiO @milenapavl and @LonnekeScheffer will share their experiences on building a large bioinformatics platform this week at Nordic computational biology talks series. Welcome!
Announcing the NAPI Kick Off Seminar! Join us on Friday 5th March to learn more about NAPI and how we can provide valuable expertise for a broad range of research projects. Full program and registration details available at https://t.co/lFPwvXBP4a Please share.
Laser capture microdissection combined with quantitative MS-based #proteomics of #celiac intestinal epithelium reveals low-level inflammation in patients that respond strongly to gluten🌾🍞 https://t.co/lqHSDf0dgp @JCoDiRC @PCFOUSOslo
Do you know of anyone interested in pursuing a PhD on how machine learning code can be made more maintainable and long-lived? Opening in Oslo: https://t.co/OjZpWI1pEp