Postdoctoral Researcher in the @drjosephpowell lab at @GarvanInstitute using sc-omics to understand various ILDs | @crepulmfibrosis Fellow | Views are my own
I’ll be giving an oral talk on this TenK10K multiome project at #ESHG2026 at 11:45am, Jun 14 in Room F1-3 (session C17.6). Join me if you’re interested in caQTL/eQTL mapping, GWAS "missing regulation", multiomics integration & our TenK10K cohort! Happy to chat 1-on-1, plz DM me.
I am happy to share the updated preprint of our TenK10K multiome project. https://t.co/MQcxknvB8m. The full caQTL summary from 922 donors and 3.5M nuclei is now available for download, plus many key summary results! Lots of new analyses since v1. Quick tour of what's changed 👇
🚀 New in Communications Biology:
Generative models of cell dynamics - from Neural ODEs to Flow Matching
https://t.co/6hEj5pchsg
We discuss modeling single-cell dynamics beyond snapshots: from cont-time Neural ODEs to simulation-free flow matching for scalable pop modeling.
🚀 New preprint!
The Human Cytokine Dictionary - 9.7M cells, 12 donors, 90 cytokines - our largest human single-cell perturbation atlas yet. Users can map cytokine activity in their own data. Huge thanks to Lukas, Sören, Larsen, Parse Bio & Seelig lab!
🔗 https://t.co/tB0teJoGez
New preprint alert: https://t.co/RugxCYzlSH. Excited to share our analysis on the impact of genetic variants on single-cell chromatin accessibility in blood, using scATAC-seq and WGS from over 1,000 donors and 3.5M nuclei as part of TenK10K phase 1 🧬
🧵👇 (1/n)
1. 🚨New preprint: https://t.co/LFazdldaPY.
We explored causal effects of gene expression in immune cell types on complex traits and diseases by combining single-cell expression quantitative trait loci (sc-eQTL) mapping in 5M+ cells from 1,925 donors in TenK10K study and GWAS. 🧵
🧬Oz Single Cell Hackathon 2025🧬 Join us at the Uni of Sydney 19-21 May before the Oz Single Cell conference! Join us to tackle challenges in scMultiomics integration, viz & predictive modeling.
Details 👉 https://t.co/w7yOQA0lC8
#OzSingleCell#ozsinglecell25@ozsinglecells
Time's running out to submit an expression of interest for the 2024 @ozsinglecells hackathon in Sydney Dec 9-10! Will use Scale Bio data from stem cell-derived cardiomyocytes to develop tools for temporal dynamics.
Don't miss out, submit an EOI by Oct 15: https://t.co/IRq698sYhb
Calling all researchers interested in developing better tools for understanding cellular dynamics across time in single cell experiments. We’re hosting the Oz Single Cell Hackathon 9-10 Dec in Sydney. Fill out EOI before 10 Oct! Travel awards available https://t.co/o66qfO7AfC
Save the date! Yes, it’s happening, the next Oz Single Cell conference will be held in Sydney, 23rd - 25th May 2025. More details to follow soon. #OSC2025
@drjenlim If you like pizza, I highly recommend Lou Malnati’s deep dish! If you have time, the museum of art is an absolute must-see. They have Seurat’s Sunday Afternoon painting + Hopper’s Nighthawks (my favorite)
Delighted to share our preprint on mapping the genetic association with intra-individual variability of gene expression. We introduced a new statistical framework to identify single-cell variance eQTL and applied it to OneK1K cohort.
https://t.co/w0iBphWsVI
The Garvan Institute and Illumina are partnering on the $27 million TenK10K project to help transform the treatment of complex diseases, starting with autoimmune diseases.
@illumina @illuminainc @drjosephpowell
Find out more: https://t.co/Xox1ZCos1z
My first conference after moving to Australia was definitely one to remember! Great talks & posters and phenomenal people #GenomeEra#ozsinglecell23
Thrilled to share a new chapter in my journey! I've accepted a postdoc role in the @drjosephpowell lab at @GarvanInstitute in Sydney, Australia, where I'll use single cell transcriptomics to study complex diseases like interstitial lung disease. Here's to the next adventure!