Now out @Nature, our paper on HiDEF-seq: single-molecule DNA sequencing that resolves single-strand changes (mismatches and damage)! https://t.co/4dPi0CpiAl
Excited to announce that our study "Spatial enhancer activation influences inhibitory neuron identity" is now online in Nature Neuroscience https://t.co/xgCajFySc7 Big thanks to the Winkelmann (@HelmholtzMunich@TU_Muenchen) & Torres (@CNIC_CARDIO) labs for the collaboration! 1/7
🧬 Preprint 🧬
Most mutations begin as a change in only one of the two DNA strands.
To see these single-strand precursors of mutations, we developed single-molecule sequencing that achieves single-molecule and *single-strand* fidelity.
https://t.co/8Eyznw7voq
🧵⬇️
1/11
Hundreds of genes have been associated with autism & neurodev disorders
But how do these genes impact specific stages in human development?
In a new preprint, @XianglingM took a bold approach & developed CRISPR screens in #assembloids to map 425 genes on interneuron dev stages 👇
Happy to share that I will be joining the Neuroscience Research Training Program (NRTP) for Psychiatry residency @YalePsych. After nearly a decade at NYU I am very excited for this next chapter. I am so grateful to my family, friends and mentors for helping me get here!
🗣️Calling all undergrads! Applications are open for our immersive, paid, 10-week summer research training program in neuroscience for students from diverse backgrounds.
Apply by March 15th 👇
https://t.co/OlHEPxxICM