Ravi Muddashetty Lab

Neurons | Ribosomes | RNA

[Ravi Muddashetty Lab @RaviMLab]

🚨 Hiring Research Candidate 🧠
DBT-funded project on epitranscriptome regulation in neurons at CBR (IISc), Dr. Ravi Muddashetty lab.
Molecular biology background + neuroscience interest required (experience preferred).
📩 Apply: [email protected]
⏳ Deadline: 10-04-2026

[Ravi Muddashetty Lab @RaviMLab]

🚨 Exciting new publication alert! 🧠 Our lab uncovers how mGluR activation restores APOE4-induced deficits in neuronal protein synthesis and synaptic activity via the mTOR–pRPS6 pathway.
Read more 👉 https://t.co/CugbFybrlN
#Neuroscience #Alzheimers #SynapticPlasticity

[Longevity India @Longevity_IISc]

How does the brain shape how long and how well we live?🧠

Join our Webinar as we dive into Brain Aging & Longevity with leading neuroscientists and innovators!

📅 4th Nov 2025 |🕓 4:00 PM IST

Register now & drop your questions for our panelists: https://t.co/QHKKd6ZgDl

[Prof. Nikolai Slavov @slavov_n]

A compelling illustration of the difference between mRNA abundance, ribosome density and protein abundance.

[Ravi Muddashetty Lab @RaviMLab]

In RNA Biology: FMRP regulates rRNA 2′O-methylation during neuronal differentiation. FMRP–snoRNA interactions shape ribosome epitranscriptomic states; loss of FMRP alters stepwise 2′O-Me dynamics, disrupting translation control in Fragile X Syndrome.
https://t.co/ENfJRhD6FG

[Ravi Muddashetty Lab @RaviMLab]

Join our team at IISc!
CBR-funded Postdoc position in dementia research using human iPSC models (Prof. Ravi Muddashetty).
PhD in cell bio/neurosci + stem cell & CRISPR experience wanted.
Apply: CV + 2 refs to [email protected].
Learn more: https://t.co/KkQqFllz2P

[Ravi Muddashetty Lab @RaviMLab]

HIRING JRF! Join our team at CBR for a project on 'Mitochondrial translation dysregulation in Alzheimer’s Disease.' Send your CV and two references to [email protected] by August 8, 2025. #Alzheimers #JRFHiring #Mitochondria

[Ravi Muddashetty Lab @RaviMLab]

@bindushreekr presenting her PhD work at the Indian Academy of Neuroscience meeting at NIMHANS #IAN24

[bioRxiv Neuroscience @biorxiv_neursci]

Transcriptome-wide mapping of small ribosomal subunits elucidates scanning mechanisms of translation initiation in the mammalian brain https://t.co/wb0Z6of0tY #biorxiv_neursci

[Poonam Thakur @poonam_thakur6]

The No Garland Neuroscience Meeting is back! Join us @tvmiiser from December 5-8, 2024. Follow @NGN_2024 for regular updates! 🧠 Register & submit your abstracts now. @AmruthaSwamina1 & I can't wait to welcome all #neuroscience enthusiasts to our campus.
https://t.co/pkFgOXgEdi

[Palakodeti Lab @Palakodeti_Lab]

Delighted to share our latest preprint led by @MNinochkaDsouza and @Naveenkcg which reveals FMRP's role in regulating rRNA 2’O-methylation during neuronal differentiation, impacting ribosome function and protein synthesis. @DPalakodeti @RaviMLab https://t.co/QUojtnHEBy

[Sangeeta Nath @NathSangeeta]

See our latest publication by @abinayar28 https://t.co/mmCN7KLe4N on how neurodegenerative stress facilitates toxic materials sharing with neighbours through membrane nanotubes. It is a product of great collaboration efforts. Thanks to @SivaramanLab @RaviManjithaya @RaviMLab.

[Ravi Muddashetty Lab @RaviMLab]

Excited to share our current findings published in @LSAjournal ! Congratulations to @R_Sarayu , Bindushree and Nisa. Well deserved!

[LifeScienceAlliance @LSAjournal]

This work highlights the different calcium channels involved in controlling protein synthesis in neurons, and shows the dysfunction of this process in Alzheimer's disease neurons @CBR_IISc @RaviMLab @R_Sarayu https://t.co/M8IZF38yAC

[LifeScienceAlliance @LSAjournal]

This work highlights the different calcium channels involved in controlling protein synthesis in neurons, and shows the dysfunction of this process in Alzheimer's disease neurons @CBR_IISc @RaviMLab @R_Sarayu https://t.co/M8IZF38yAC

[James Clement @jamesclementjnc]

A potential therapeutic target for ASD: downregulation of histone acetylation (could be a signature of SYNGAP1-related asd #autism #brain #drug #disease #therapy https://t.co/pHvNrS3ez7

[Shweta @shramdas]

Happy to host postdocs in our group--we work on genetics of Indian populations in the context of aging and neurodegeneration. Please reach out if interested!

[Minhaj Sirajuddin @ms_chirps]

New paper from @cytoskeletonlab Drisya Dileep @AmmuDris in collaboration with Tabish Syed, Kaleem Siddiqi @mcgillu @quorumetrix @Dhan_inStem
https://t.co/hKkUSB5eVu
We combine tissue clearing, volumetric imaging & computer vision to obtain micron-scale heart myofiber organization

[Abinaya Chandrasekar @Abinaya113]

Happy to share our new article on the #CACNA1A variant from our group.

https://t.co/9Oq7gl8ylZ

#Freudegroup #epilepsy #CACNA1A #epilepsyeducation

[Abinaya Raghavan @abinayar28]

Curious to know more about cell-cell transfer through Tunneling nanotubes and their effect on alpha- synuclein induced toxicity? Check out the link in the thread

@PhDVoice @AcademicChatter @OpenAcademics @ThePhDPlace @PhD_Genie #AcademicTwitter

[Centre for Brain Research, IISc @CBR_IISc]

We are delighted that our faculty member @BratatiKahali has been recommended for the IA Intermediate Fellowship, which will help harness the power of large-scale #genetic analyses to study the interplay between metabolic risk factors and cognition to gain insights into #dementia.