Miguel Rodríguez de los Santos

Biologist with a special interest in human genetics and neurodevelopmental disorders. Postdoctoral researcher in the Breen Lab @IcahnMountSinai @SeaverAutism

[Miguel Rodríguez de los Santos @RodrigMig]

My first first-author publication as a postdoc “Divergent landscapes of A-to-I editing in postmortem and living human” is finally out in #NatureCommunications. 🤩
Scroll down for the most important insights. (1/11) https://t.co/Gl3bjAP5rn

[Maurizio Scaltriti @ScaltritiLab]

In 20 anni di congressi ho assistito a due standing ovation. La prima per un farmaco che ho contribuito a sviluppare. La seconda adesso.

[Miguel Rodríguez de los Santos @RodrigMig]

@vmolinav No se si tu o tu querida Corina Machado no se han enterado, quien no quiere elecciones en Venezuela ahora mismo es la propia administración de Trump, al quien le regaló su bonito premio de la paz, la derecha venezolana y a quien la apoyan es un chiste!

[Adriano Bolondi, PhD @adrianobolondi]

🚨JOB ALERT🚨PLEASE SPREAD and RT

Searching for a motivated Master’s student @LabBoke @CRGenomica @the_prbb to investigate how proteostasis in oocytes influences dormancy and fertility.
Reach out to me ([email protected]) to join us in sunny Barcelona!

See details below👇

[Miguel Rodríguez de los Santos @RodrigMig]

Thank you for inviting me @crisprscan @CABD_UPO_CSIC , it was a pleasure to share some insights about my research and to exchange ideas.

[Centro Andaluz de Biología del Desarrollo @CABD_UPO_CSIC]

Great start of the #CABDseminars 2025/2026 with the talk of @RodrigMig!
Dr. Rodriguez gave an insight of the studies from his PhD and Postdoc work focused on rate diseases. He was invited by @crisprscan
Thanks for coming Miguel!

[Miguel Rodríguez de los Santos @RodrigMig]

@DeRubeisLab @mgarcia_forn @NICHD_NIH @BiologyOpen @MichaelAFlores_ Congratulations!! 🎉

[Miguel Rodríguez de los Santos @RodrigMig]

@adrianobolondi @LabBoke @CRGenomica @the_prbb In bocca al lupo, Adri!

[Michael S. Breen @breenPsychGene]

Our recent work with @SeaverAutism evaluating peripheral transcriptomic effects of #ketamine in children with #ADNP syndrome. @MountSinaiPsych @SinaiGenetics @SinaiBrain

https://t.co/LPdh7F1cvE

[Miguel Rodríguez de los Santos @RodrigMig]

Microglia cells adapt to the circadian rhythm by going through transcriptional, proteomic and phenotypic alterations. Mattei et al. convincingly suggest: Mind the time, when you study #Microglia!!Wonderful work @DanieleMattei4 👏

[Daniele Mattei, PhD @DanieleMattei4]

Mind The Time! What time do you collect #microglia from your preclinical model for downstream analyses? Microglia undergo #transcriptional, #proteomic and #functional adaptations to the wake and sleep phases🧵https://t.co/KOFu1C1BLB

[Friedman Brain Institute @SinaiBrain]

EXCITING NEW STUDY by @IcahnMountSinai's @RodrigMig @panos_roussos @aw_charney @breenPsychGene, et al. shows major differences in RNA editing btwn living & postmortem human brains! Discovery may play significant role in treating brain diseases @NatureComms https://t.co/wa3iaRjNQQ

[Icahn School of Medicine at Mount Sinai @IcahnMountSinai]

A Mount Sinai study reveals major differences in #RNA editing between postmortem and living prefrontal cortex brain tissues, shaping the development of diagnostics and therapies for #brain diseases: https://t.co/ZJoImYdPZY

@breenPsychGene @RodrigMig @aw_charney @MtSinaiNeuromod

[Michael S. Breen @breenPsychGene]

Our new article on A-to-I editing reveals differences in editing levels between postmortem and living brain tissues. Led by @RodrigMig & the Living Brain Project team: https://t.co/ii7SnRET0n

#RNAediting #ADAR #RNA @SinaiGenetics @IcahnMountSinai @MountSinaiPsych @SinaiBrain

[Miguel Rodríguez de los Santos @RodrigMig]

@DeRubeisLab Thank you so much, Silvia! :)

[Miguel Rodríguez de los Santos @RodrigMig]

My first first-author publication as a postdoc “Divergent landscapes of A-to-I editing in postmortem and living human” is finally out in #NatureCommunications. 🤩
Scroll down for the most important insights. (1/11) https://t.co/Gl3bjAP5rn

[Miguel Rodríguez de los Santos @RodrigMig]

@nicolewanalee Thank you so much, Nicole! :)

[Miguel Rodríguez de los Santos @RodrigMig]

And last but not least: This study is part of the Living Brain Project at @IcahnMountSinai and would have not been possible with all the collaborators involved. I want to thank you for all the support. A special thank you goes to my supervisor and mentor @breenPsychGene

[Miguel Rodríguez de los Santos @RodrigMig]

In conclusion, we were able to reveal differences in AtoI editing between living and postmortem brain driven by hypoxia and inflammation after organismal death. Our findings do not negate but instead, provide missing context for using postmortem brain tissues to study #RNAediting