The Rullo Lab

Student-run Twitter for the Rullo Lab @McMasterU, located in the Michael DeGroote Centre for Learning and Discovery (MDCL)🧪
Find us at:

[Anthony Rullo: chemically modulating proximity @LabRullo]

Happy to share some recent work in the lab developing covalent peptides to reprogram antibody targeting function https://t.co/C7BnUoehN9

[The Rullo Lab @RulloLab]

Read it here: https://t.co/JmaWxvgibD

[The Rullo Lab @RulloLab]

Exciting to see recent work from the Rullo Lab highlighted in this @BritPharmSoc editorial on the re-emergence of covalent modulation in drug discovery! 🧪

Great to see covalent chemistry continuing to expand what’s possible in chemical biology and immunotherapy.

[The Rullo Lab @RulloLab]

Very excited to share our group's latest research, published in @NatureComms, titled 'Mimicry of molecular glues using dual covalent chimeras'!
@LabRullo

Check out the full publication here: https://t.co/o2oaRzwpGx

[Anthony Rullo: chemically modulating proximity @LabRullo]

Incredibly proud of @RulloLab members Karolina Krygier, Tomas Frankovich and Anjalee Wijetunge for brilliant presentations at @qomsboc 2024!

[Centre for Discovery in Cancer Research @CDCR_Mac]

@LabRullo was cited in an independent blog on @ScienceMagazine website written by Derek Lowe titled “Induced Proximity in the Lab and in the Clinic”.

He is cited at the 4th link.
🔗https://t.co/f1VU9LQkeK

Congratulations! 👏🥳

@RulloLab @machealthsci @MacDeptMed

[The Rullo Lab @RulloLab]

Covalent bispecific molecules to engage tumor-immune proximity @LabRullo
https://t.co/4BsBZUiagD

[Anthony Rullo: chemically modulating proximity @LabRullo]

Brilliant contribution by @DASpiegel256 and co workers to induced proximity

[The Rullo Lab @RulloLab]

Congratulations to Sandra for being named CDCR’s trainee of the month!

[Anthony Rullo: chemically modulating proximity @LabRullo]

Beautiful oxaziridine based oxidative approach to tryptophan labeling ! @christhechang and toste labs https://t.co/Lom2mUqLRH

[Covalent Modifiers @CovalentMod]

Restricted Rotational Flexibility of the C5α-Methyl-Substituted Carbapenem NA-1-157 Leads to Potent Inhibition of the GES-5 Carbapenemase https://t.co/UmrSYfN7B2

[Anthony Rullo: chemically modulating proximity @LabRullo]

A beautifully written comprehensive review on the use of proximity induced chemistry to generate novel protein therapeutics by @Han_Xiao2016
https://t.co/7OhDse80HJ

[Guillaume Laconde @Glaconde34]

Subunits of an E3 Ligase Complex as Degrons for Efficient Degradation of Cytosolic, Nuclear, and Membrane Proteins | ACS Synthetic Biology https://t.co/JTBtkEDb7e

[Anthony Rullo: chemically modulating proximity @LabRullo]

Excited to present our work in covalent bifunctionals, for inducing cell-cell proximity in immunology ! #Covalent #proximity

https://t.co/0IpODoEEDs

[Anthony Rullo: chemically modulating proximity @LabRullo]

Excited to return to beautiful Boston this Tuesday and see great colleagues working in covalent drug development and proximity inducing molecules!
https://t.co/eMI5psVBwP

[McMaster Immunology @MacImmunology]

Join us tomorrow for our Work in Progress Seminar!

[The Rullo Lab @RulloLab]

Check out our newest publication featuring @BenjaminLake15 ! Congratulations!

[Anthony Rullo: chemically modulating proximity @LabRullo]

Happy to share our most recent contribution coupling covalency with carbohydrate binding for immune proximity induction.
https://t.co/JA54P8OstH

[McMaster Immunology @MacImmunology]

Join us tomorrow for WIP, featuring Annika Yardy from the Larche lab and Danielle Libera from the @jfekoenig @Jordana_Lab!

[Anthony Rullo: chemically modulating proximity @LabRullo]

A must read

[Anthony Rullo: chemically modulating proximity @LabRullo]

⁦Beautiful review ⁦@Han_Xiao2016⁩ ! https://t.co/jvlDE8XLHO