SA/UK ADD Hub

SA/UK Antimicrobial Drug Discovery Hub.
Funded by the @MRCza & @NewtonFund through @The_MRC. Harnessing natural product diversity to combat AMR.

[SA/UK ADD Hub @SA_UKADDHub]

The SA/UK ADD Hub's newly launched website!
Visit it now, here -->
https://t.co/bigKnOIqwV
Find out all about our Newton Fund AMR Project, the Consortium's news, upcoming events and more!
Made possible by @MRCza, @NewtonFund, @The_MRC

[SA/UK ADD Hub @SA_UKADDHub]

Prof Rui Krause - Passing of an ADD Hub Member
See here for more ---> https://t.co/AtaEAUuoQA

[SA/UK ADD Hub @SA_UKADDHub]

Race Against Resistance: The Life And Death Struggle To Save Antibiotics... https://t.co/Qv53vV58SE via @YouTube

[Mat Upton @mat_upton]

I’ve come to @thembauk on Plymouth Hoe for the launch of UK’s 1st Marine Microbiome Centre of Excellence! Imagine all the amazing microbiology to be discovered out there…we’re looking for new #antibiotics in #marinefungi with @sea_bugs @SA_UKADDHub

[SA/UK ADD Hub @SA_UKADDHub]

Sharing the WHO's Science in 5 Podcast. Take a moment to listen to what you need to know when taking #antibiotics 💊.
#antimicrobialstewardship

https://t.co/3p96vaHt9n

[SA/UK ADD Hub @SA_UKADDHub]

WHO's Science in 5: Microbes are becoming resistant to antibiotics https://t.co/P5yoRhJLu7 via @YouTube

[SA/UK ADD Hub @SA_UKADDHub]

@NewtonFund It is most exciting that we get to do this research and collaborate with other passionate scientists in the field of #AMR and #NPdrugdiscovery!

[Natural Products BioHUB - Swansea University @SwanseaBioHUB]

‘I work in the field of natural products produced by fungi’

Introducing Dr Claudio Greco - his current research examines a pathogenic filamentous fungus that has co-evolved with leaf-cutter ants 🍄🐜

https://t.co/Er7qkd2psw

@BBSRC #bioscience #research

#fungi

[CDC Antimicrobial Resistance @CDC_AR]

#DYK most cases of #Cdiff occur while you’re taking #antibiotics or not long after you’ve finished? Protect yourself and your loved ones from this life-threatening infection. https://t.co/z2MKVLYM4v #CdiffAwarenessMonth

[Wellcome @wellcometrust]

New @WHO data shows that in 2021, #tuberculosis killed someone roughly every 20 seconds.

The number of people falling ill with TB and dying from it increased.

While the data is devastating, it is sadly unsurprising.

[1/7]
https://t.co/pZd3aTSky2

[SA/UK ADD Hub @SA_UKADDHub]

And so the 2022 #H3DSymposium comes to a close aftera hugely stimulating and inspiring conference! Thank you to all who made this opportunity possible to network and engage on the critical topics on #drugdiscovery in Africa, and further broad.

[SA/UK ADD Hub @SA_UKADDHub]

Overcoming infectious diseases is a complex and dynamic issue that require novel approaches, multiple approaches and out-of-the-box thinking to tackle #drugdiscovery in light of the #AMR global health issue.

[SA/UK ADD Hub @SA_UKADDHub]

Roi Avraham of @WeizmannScience considers the interaction between pathogens and host, using a Dynamic Deconvolution approach for single cell RNASeq to analysis the impact of human variation on cell-specific pathogen responses.

[SA/UK ADD Hub @SA_UKADDHub]

"Combination therapies is what we should aim for." Anna Hirsch's research tackles #drugdiscovery invesigating a Patholocker approach as adjunctive therapy to antibiotics for hospital-acquired P. aeruginosa infections.
#H3DSymposium

[SA/UK ADD Hub @SA_UKADDHub]

Rolf Miller opens the AMR #drugdiscovery session sharing his lab's work on identifying novel NPs from predatory myxobacteria of soil origin. He uses phylogenetically distant strains from those previously characterized to prioritize novel NP discovery.
#H3DSymposium

[SA/UK ADD Hub @SA_UKADDHub]

Following a jam-packed day of #drugdiscovery science, we celebrate the amazing research currently underway in Africa at the #H3DSymposium Conference Dinner with a delicious #proudlysouthafican spread.

[SA/UK ADD Hub @SA_UKADDHub]

Such an interesting and hugely topical discussion raised by @mathewnjoroge - how does genetic variation in African populations affect drug metabolism and deposition, and it's impact on development of resistance or drug toxicity.

[SA/UK ADD Hub @SA_UKADDHub]

"A good assay leads to good analysis, which supports good compound analogue design" for #drugdiscovery of XDR TB. Brendan Cowley @MERCK Sharp and Dohme, discusses improving the efficacy and selectivity of linezolid.
#H3DSymposium

[SA/UK ADD Hub @SA_UKADDHub]

#H3DSymposium

[SA/UK ADD Hub @SA_UKADDHub]

Clif Barry of the @NIH challenges us to rethink our understanding of treating TB to sterility - is this achievable, particularly with our existing treatment regimens? This is an important consideration in the journey of #drugdiscovery for this critical infectious disease.

[SA/UK ADD Hub @SA_UKADDHub]

Clif Barry of the @NIH challenges us to rethink our understanding of treating TB to sterility - is this achievable, particularly with our existing treatment regimens? This is an important consideration in the journey of #drugdiscovery for this critical infectious disease.