https://t.co/1uBaVe0Zl2
Therapeutic Transplantation of Mitochondria and Extracellular Vesicles: Mechanistic Insights into mitochondria bioenergetics, redox signaling, and organelle dynamics in preclinical models.
Different types of mitochondria transit between cells
Featuring work by @BrestoffLab and other contributors to this exciting field
https://t.co/VsADa12At8
We probed whether there are other anion currents in mitochondrial associated membranes.
https://t.co/yxXNE50ow8
Undergrads (Denis and Mayukha) performed initial experiments, and manuscript was shaped by Shridhar and Satish (postdocs)
@BiophysJ@osuresearch@OhioStatePCB
In mitochondria, respiratory supercomplexes (blue) pump protons across crista membranes to create an electrochemical gradient, fueling adenosine triphosphate (ATP) synthase (pink) to regenerate ATP—the energy currency of life.
Now, cryo–electron tomography captures these supercomplexes in their native organization, illuminating how the coordinated action of these molecular machines drives life’s fundamental energy conversion.
Learn more this week in Science: https://t.co/2hN9Vb6Sf0
Check out my group's new paper suggesting the inactivation mechanism of the ATP synthase leak channel! It comes with 14 supplementary figures and 16 cryo-EM maps and models. I couldn't have dreamed of a better lab and colleagues to work with.https://t.co/LrCQkFmnIb
The bioelectric aspects of mitochondria are of particular relevance on all levels of organization of an organism.
Mitochondria not only stand out because of their high membrane potential but also since they can form mitochondrial networks that can be electrically coupled. Mitochondria can be regarded as electrical transmission fibres.
https://t.co/nXlT6Lm8qS
The brain is full of mitochondria!
But how many, and where?
Different types of mitochondria specialize for energy transformation and other functions
In MitoBrainMap v1.0 we provide the first maps of mitochondrial content and OxPhos capacity across the human brain
Join us for exciting Subgroup dinner at Bottega Louie 630 pm on Feb 15 2025
https://t.co/mjXB0qhbUc. Just scroll down to your Subgroup’s dinner to get the specific link!
https://t.co/aF74TDwqh5