Sam Snider

Neurocritical care attending at BWH in Boston. Practical applications of advanced neuroimaging. Opinions here are mine.

[Brian Edlow @ComaRecoveryLab]

Two new tools to map the human brainstem:

nuclei: https://t.co/XafKSGOGAZ
bundles: https://t.co/Js3qxETEZs

code: https://t.co/oZr3eb4TwN
https://t.co/17a64IQrhA

@olchanyi @JuanEugenioIgl1 @MGHMartinos @MGH_CNTR @MGBResearchNews @MIT

[Sam Snider @SamBSnider]

See our response to concerns raised about the validity of lesion network mapping here. IMO, initial critique published in @NatureNeuro does not hold up to scrutiny.

[Michael Fox @foxmdphd]

A recent paper in @NatureNeuro raised concerns about the lesion network mapping method. Our team of 16 coauthors analyzed >1000 lesions and 34 symptoms and found that "The methodological foundations of lesion network mapping remain sound" https://t.co/kkmpKFh3eE

[Michael Fox @foxmdphd]

A recent paper in @NatureNeuro raised concerns about the lesion network mapping method. Our team of 16 coauthors analyzed >1000 lesions and 34 symptoms and found that "The methodological foundations of lesion network mapping remain sound" https://t.co/kkmpKFh3eE

[Mass General Brigham Research @MGBResearchNews]

A new study shows that signature patterns of brain activity may help predict recovery from #TBI.

Read more from @SamBSnider and colleagues in @PNASNews: https://t.co/jPeNRMB8SO

[Michael Fox @foxmdphd]

~10 years ago we published a paper on anticorrelated brain networks, but are they useful clinically? New work from @SamBSnider @Brain_Circuits @ComaRecoveryLab in @PNASNews suggests they predict recovery from severe brain injury. Thread below:

[Sam Snider @SamBSnider]

paper here: https://t.co/NM9SSzrDOk

Collaboration between @BWHNeurology, @MGHNeurology, @imperialcollege, and the EU.

@foxmdphd @Brain_Circuits @ComaRecoveryLab @BWHNeurosurgery @Neurosharp @nsngraham

2/2

[Sam Snider @SamBSnider]

We report a new biomarker for recovery from moderate/severe TBI:

The synchronized toggling of activity between "task-positive" and "task-negative" brain networks.

Out today in @PNASNews

1/2

[Shan Siddiqi @shansiddiqi.bsky.social @shansiddiqi]

Last week I lost a friend.

But the rest of the world lost a warrior.

A visionary who dedicated his life to healing the sick and relentlessly bulldozing any barriers that got in his way.

1/n

@NolanRyWilliams

[Calvin Howard @calvinwhow]

New research from @harvardmed
@brighamWomens
@brain_circuits:

We evaluated how DBS in Parkinson’s with Alzheimer’s influences cognition. Originally, it looked like DBS was deleterious for cognition in Parkinson’s, but could be beneficial in Alzheimer’s.

[Sam Snider @SamBSnider]

@neuromichael Amazing pictures

[Sam Snider @SamBSnider]

@BWHNeuroICU @Brain_Circuits @_Anesthesiology

[Sam Snider @SamBSnider]

The BIS monitor is used in ORs around the world.

In patients comatose after cardiac arrest, we virtually-emulated BIS monitor output from clinical EEG.

A neural network trained on this data out performed clinical gold-standard at predicting recovery.

https://t.co/7b9MatDTiM

[Anesthesiology Journals @_Anesthesiology]

In a new cover study, Snider et al. tested if internal EEG subparameters extracted by the BIS monitor—a device commonly used to estimate depth of #anesthesia intraoperatively—could be repurposed to predict recovery of consciousness after cardiac arrest: https://t.co/4zhp0qBDTx

[Sam Snider @SamBSnider]

@AmarDhand @PNASNews Congrats. Can’t wait to read it

[Frederic Schaper @fredschaper_]

Is generalized epilepsy a seizure of the whole brain or a specific brain network?

In our new paper out now in @NatureComms we investigate this by combining brain abnormalities and DBS with the human connectome.

Paper: https://t.co/hlQVXigDED

A 🧵 below:

[Brian Edlow @ComaRecoveryLab]

Visualizing Effective Connectivity in the Human Brain

Preprint: https://t.co/ZiORqUJmHs
Code: https://t.co/lKtRg6pCsT
YouTube video: https://t.co/ISwd5ahs7M
Download video & figures: https://t.co/PVlPXDoAVY

Led by #XanderAtalay & #TeoFecchio

@MGH_CNTR @MGHMartinos @MGHNeuroICU

[Sam Snider @SamBSnider]

@peirong26 @JuanEugenioIgl1 @AnaLawryAguila Great work! Does it output a label map for anomalous areas?

[Spaulding Rehab @SpauldingRehab]

Spaulding awarded two #TBI researchers $400K each in support of their new studies to understand mechanisms underlying disorders of consciousness & identify effective treatments. Learn about the Innovative Treatments in Disorders of Consciousness program: https://t.co/scjv0oS9KL.

[Sam Snider @SamBSnider]

@dbfisch @GreenJournal Awesome- looking forward to reading this

[Sam Snider @SamBSnider]

@WillManidis Have never heard it articulated like this- totally agree. So very different from an exam question.