We aim to shed new light on the complex networks formed in #melanoma, and learn how we can utilize this information to treat melanoma patients
@WeizmannScience
Proud of @samuels_yardena for her fascinating plenary session at the @AACR annual meeting in Chicago! A great thank you to the program committee chairs, Drs. Matthew G. Vander Heiden and Lillian L. Siu for this amazing opportunity.
@mvh_lab@lillian_siu#AACR25#AACR2025
Thrilled to share our work in Cancer Cell! Huge thanks to my PI and mentor @samuels_yardena ,OsnatBartok, and our collaborators @chrismcginnis,@Satpathology , Andreas Schlosser,@EytanRuppin & more. We reveal how impaired translation fidelity enhances anti-tumor immunity!🧵(1/8)
In a study published in @Cancer_Cell, researchers from @Samuels_lab manipulated cancer cells into making themselves visible to the immune system, creating a new approach that gives hope to patients with previously untreatable disease>>https://t.co/V90RKJ6U9M @samuels_yardena
The Various Layers of Intratumor Heterogeneity and Their Impact on Tumor Immunity:
Yardena Samuels will address this topic in a plenary session on Targeting the Cancer Ecosystem (Tuesday, April 29) at #AACR25. Learn more:
https://t.co/DKaZw1uxwc
@samuels_yardena
Our new paper on Macrophage Migration Inhibitory Factor (MIF) as a key regulator of immune evasion in melanoma, is now published in @CD_AACR (full study here:https://t.co/8JiVP0buDq)
Step-by-step breakdown of this exciting research follows:
7/8 Our findings suggest that MIF expression is an important determinant of aggressive tumor growth in low-ITH tumors in melanoma and could lead to new strategies for treating patients with homogeneous, high-MIF-expressing tumors that don't respond to immune checkpoint therapy.
New study in @Samuels_lab, published in Cancer Discovery, reveals a key player in the development of aggressive melanoma tumors: a small immune system protein called Mif. Findings promise to open new directions of therapy >> https://t.co/XP2bgKh1Xm
@samuels_yardena
Congratulations to our very own Sapir Cohen Shvefel! Her paper on Macrophage Migration Inhibitory Factor (MIF) as a key regulator of immune evasion in #melanoma, is now published in @CD_AACR ! Full article here: https://t.co/8JiVP0buDq
Thrilled to share that our new paper on Macrophage Migration Inhibitory Factor (MIF) as a key regulator of immune evasion in melanoma, is now published in @Cancer Discovery! Find the full study here: https://t.co/Gl88qcQ7fy