Sarah Chang

MD/PhD Student at @HarvardMITmdphd. Grad student in @mvh_lab, interested in cellular metabolism and bioenergetics

[Peggy Hsu MD PhD @PeggyPHsu]

So proud of our work (@BrianTDo1 and @mvh_lab) exploring how nucleotide metabolism can impact cell fate which is now @Dev_Cell. This was a fascinating and rewarding journey that started in metabolism and led us far afield (plus add in a pandemic and my move @UMich).

[Allen Su @xiaofengsu]

Please check out this important work from my great friends/collaborators at @mvh_lab. Congrats on the team! @BrianTDo1 @PeggyPHsu

[Evan Lien @eclien]

Happy to share the first preprint from the lab! We describe how extracellular lipid availability regulates a polyunsaturated fatty acid trafficking pathway in cancer cells that influences ferroptosis sensitivity. Check it out! 👇
https://t.co/ZfvIyYRwuK

[Matt Chang @mpchang17]

Missed Tackle Opportunities won the 2024 #BigDataBowl ! So proud of the team for the hard work and a stellar presentation at the #NFLCombine

Thank you @StatsbyLopez, @DataWithBliss, @Ally_Blake3 and the #NFL for such an incredible experience. @NextGenStats your move👀

[Rahul Gupta @rahulg603]

Out today @Nature – our analysis of the influences of common nuclear DNA variation on mitochondrial DNA copy number and heteroplasmy across >250,000 people across two biobanks! https://t.co/VjYsSE0BOg

[Kiera Sapp @ksapp17]

Looking for a crash course in how cellular metabolism and the mammalian cell cycle are connected? Check out this review Franny and I wrote with @mvh_lab! https://t.co/c1E1CSMY0E

[Kaitavjeet Chowdhary @kaitavjeet]

Excited to share a big part of my PhD work in preprint! We used scATAC-seq, machine learning, and genetic variation, validated with TF KOs, CRISPR-editing, and TF binding, to define the architecture of the Treg regulatory network
https://t.co/8qcYbbUSL3
(1/n)

[Sarah Chang @SarahMChang]

From the State College high school tennis courts to Dr. Badding! Congratulations Ed 🥳

[Edward D. Badding @tennisson6478]

Thanks to my lab, friends, and family!

[MVH Lab @mvh_lab]

Congratulations Dr. Kiera Sapp @ksapp17 on defending her PhD thesis "The Influence of Cellular Redox State on Mitosis"! Beautiful science and outstanding talk. We are so excited to see what bright things lay ahead for you (like winning first place in trivia)!

[Lucas Sullivan @LucasBSullivan]

Pleased to share our lab’s first primary research manuscript is now online @eLife.
If you happened to read the @biorxivpreprint version (posted one year ago today!), some of the additional findings are described below:
https://t.co/VQOGoo2sSD

[Sarah Chang @SarahMChang]

@tennisson6478 @srisantitham Congratulations Ed and team!!! So proud

[Edward D. Badding @tennisson6478]

Excited to share our group’s work on chemically modifying FeMo-co. Here we report our strategy to selectively enrich one of its seven Fe sites with 57Fe for mechanistic studies of the Mo nitrogenase. Big thanks to Dmitriy, Brian, Dan, and @srisantitham.

https://t.co/IKHlxYQJ8s

[Sarah Chang @SarahMChang]

@HannahRRoach Congratulations Hannah!!! 🥳

[Sarah Chang @SarahMChang]

@AnnabelZWang Congrats Annabel!!

[Sarah Chang @SarahMChang]

An absolute triumph from @chidley_chris. Congratulations!!! 🥳🥂🤩

[Chris Chidley @chidley_chris]

I’m excited to share a new #cancer #metabolism preprint where we explore nutrient transport in cells and tumors in CRISPRi/a screens.
https://t.co/10aNyqUV6E
Our question:
How do small molecules like nutrients and drugs get in and out of cells?
🧵(1/12)

[Alicia Darnell @amcdarnell]

A tour de force by @chidley_chris - mapped transport mechanisms for every amino acid that cells care about in culture, did rigorous import/export rate measurements, and figured out which actually matter in a physiological env. Really cool surprises – serotonin blocks ferroptosis!

[Muir Lab @Muir_Lab]

Congrats to Mark Sullivan (not on twitter)!! Super cool new metabolism study identifying microenvironment-induced synthetic lethalities that can be targeted to treat antibiotic resistant bacterial infections!

[Alicia Darnell @amcdarnell]

Super honored to be a new fellow. Thanks so much @HRiAction for supporting my work and congrats to the other fellows, can't wait to meet you!

[Sarah Chang @SarahMChang]

@jacobranderso @BloodJournal congrats Jacob!! beautiful 🤩

[Sarah Chang @SarahMChang]

Alejandra was an absolute joy to work with! Bright things ahead for her ✨☀️

[Koch Institute at MIT @kochinstitute]

Through curiosity, collaboration, and mentorship, @mvh_lab MSRP-Bio student Alejandra Rosario is working toward a deeper understanding of glioblastoma metabolism and more effective cancer therapies.

https://t.co/tibkK9stZj