Sebastian Preissl

Professor, Pharmacology @UniGraz, Group leader @UniFreiburg, previously @CEpigenomics, epigenomics, technologies, aging, heart, kidney, macrophages

[Intensive Care Medicine Experimental (ICMx) @ICMexperimental]

❓What is the course of 🫀 remodeling and recovery during and after prolonged catecholamine treatment?
🐭 assigned to 14 days soprenaline+phenylephrine
🧬⬆️LV contractility/🫀fibrosis+hypertrophy
💊Targeted therapeutic approaches
🔓Read more: https://t.co/0jrH8KI3nC

[nature @Nature]

Nature research paper: Spatially organized cellular communities form the developing human heart https://t.co/dJbVm4jC8f

[Raphael Reuten @RaphaelReuten]

Our #spatial #filtering #tool might be useful for a broader audience to dissect #mechanics #patterns in #AFM force maps
https://t.co/fVZxUDIczZ
@CIBSS_UniFR @UniFreiburg @NatRevMater

[Universität Freiburg @UniFreiburg]

Ob Genomanalyse von Tierarten oder des Coronavirus – der in Freiburg beheimatete europäische #GalaxyServer ist ein wichtiges Werkzeug für datenintensive Forschung. Bioinformatiker Björn Grüning erklärt, warum. https://t.co/O4ZmyIZNOD @bjoerngruening @galaxyproject #galaxyproject

[Journal of Molecular and Cellular Cardiology @JMCCardiology]

Beautiful cover image for February, courtesy of authors @UniFreiburg, shows whole mount image of the pacemaker cells, M2R, and glycocalyx of the cell membrane of a mouse sino-atrial-node. See their full article: https://t.co/70UybyTfZ9

@SlisaSG @Seb11pr @CallumZgierski @sfb1425

[Circulation Research @CircRes]

Laurette et al found an efficient #AAV-based method for #CRISPRi-mediated epigenetic silencing of gene expression in cardiac myocytes in vivo and in vitro. Learn more at https://t.co/9fmdRSN3Kj

@Patrick_Irt @Ralf_Gilbach @Eileen_Furlong @LisaM_Weiss

[nature @Nature]

Nature research paper: Single-cell analysis of chromatin accessibility in the adult mouse brain https://t.co/Iu7wUGC2BP

[nature @Nature]

This week in Nature: Brain maps - High-resolution cell atlas of entire mouse brain offers genomic, epigenetic and anatomical insights

Browse the full issue: https://t.co/cg9WdqoIcV

[Sebastian Preissl @seb11pr]

@KierdorfLab @TRR359_PILOT Thank you for the kind words and invitation! I enjoyed it a lot!

[bioRxiv @biorxivpreprint]

Age-related structural and functional changes of the intracardiac nervous system https://t.co/uDV1YjRooQ #bioRxiv

[Science Magazine @ScienceMagazine]

In 21 papers across Science, @ScienceAdvances, and @ScienceTM, researchers with the #BICCN consortium present an atlas of the human and nonhuman primate brain in unprecedented detail.

The results uncover the genetic organization of the human brain. https://t.co/K3ePBMRzli

[MPI of Immunobiology & Epigenetics @mpi_ie]

📅 Save the date! Don’t miss the 3rd Symposium on Medical Epigenetics by CRC992 MEDEP.

18-20 March 2024 in #Freiburg (Germany)

Registration is already open: https://t.co/coUvhwrd5e

[Yang Eric Li @YangEricLi]

So excited that our work is published in Science today! 📣We profiled regulatory elements from 1.1 million cells across 42 distinct human brain regions🧠, and associated relevant cell types to 19 common neuropsychiatric disorders. @ScienceMagazine #BICCN https://t.co/MQZlP8XwVS

[Sebastian Preissl @seb11pr]

@YangEricLi @ScienceMagazine Congratulations!

[realArnoldLab @realArnoldLab]

Ancient question with a new twist!
Check our new study by Schüle, Weckerle et al. https://t.co/BhQZIMI5iL showing how TBX TFs Eomes&Brachyury specify cell lineages during gastrulation in a sequence. Eomes first dominates over Brachyury which only acts once Eomes left the scene.

[Cohesin @Xieeee4]

🍺I am so excited that my first paper is online (https://t.co/gwg6bc6l62)! Joint profiling of histone modifications and transcriptome are critical to understand the active or repressive gene regulatory network. We therefore develop Droplet Paired-Tag,

[Nature Reviews Genetics @NatureRevGenet]

Our August 2023 issue is now live!
In this Focus issue (https://t.co/wU2LPPE4dV) and its accompanying collection (https://t.co/Tls8x5qspQ), which includes older reviews, we highlight the exciting developments in single-cell omics and their transformative potential

[Sebastian Preissl @seb11pr]

Do you enjoy the study of gene regulation and the outdoors? Come join our international team in sunny Freiburg, Germany!
#phdposition #generegulation #spatial #singlecell #epigenetics #heart
https://t.co/6rEoVNP0Xj

[Cell Genomics @CellGenomics]

Robust enhancer-gene regulation identified by single-cell transcriptomes and epigenomes https://t.co/Yw4UDCVnKI

[PhD Research Training Group MeInBio @RTG_MeInBio]

Open PhD position! If you are interested in analyzing the spatial dynamics of heart failure pathogenesis through integrative analysis of single cell transcriptomes, epigenomes and subcellular spatial transcriptomes, check here how to apply!
https://t.co/ZdmR81DCaD