SerpellLab

Research groupworking on molecular basis of Neurodegeneration and Alzheimer's disease. Dementia research group. Supported by Alzheimer's society and ARUK

[SerpellLab @SerpellLab]

We were really excited to write this short article for @alzheimerssoc about AlphaFold2. Lovely work @KarenEMarshall https://t.co/gi8wuT9LHK

[Hannah Churchill @ChurchillHannah]

Thank you to @SerpellLab for their @alzheimerssociety guest blog discussing what the Alphafold artificial intelligence programme from @DeepMind could mean for #dementia research - early days but an important step https://t.co/gZ99lGwQIM

[TauRx Therapeutics @TauRx]

#Tau is a protein associated with many #brain diseases, including #Alzheimer's. @TauRx believe #education is essential in spreading awareness and understanding of how tau and Alzheimer's disease are connected.

Learn more here #targetingtau ➡️ https://t.co/FvqZAcRS5D

[SerpellLab @SerpellLab]

Delighted with this newly submitted paper!

[Mahmoud Bukar Maina PhD FRSA @mahmoudbukar]

Read our new work from @SerpellLab using PHF-core Tau fragment, showing that oxidative stress conditions that induce dityrosine crosslinking lead to the trapping of Tau intermediates, preventing them from transforming into fibrils.

[SerpellLab @SerpellLab]

Sharing our two articles from @alzheimerssoc DTC APOE research and Protein misfolding with @TauRx @SussexUni @SussexNeuro @BrainEnergyLab @OGSteele https://t.co/fE9MrrrhEg

[SerpellLab @SerpellLab]

Lovely paper from generated from a chance meeting at a conference! Well done Guna and @mahmoudbukar https://t.co/cvbIKROa8z

[SerpellLab @SerpellLab]

Frontiers | MIRRAGGE – Minimum Information Required for Reproducible AGGregation Experiments | Frontiers in Molecular Neuroscience https://t.co/b6JnJ9ocmS

[SerpellLab @SerpellLab]

Frontiers | MIRRAGGE – Minimum Information Required for Reproducible AGGregation Experiments | Frontiers in Molecular Neuroscience https://t.co/b6JnJ9ocmS

[SerpellLab @SerpellLab]

@sylvia_schroed @SussexLifeSci @SussexNeuro Welcome!

[Sylvia Schröder @sylvia_schroed]

I’m looking for a Phd student to join my lab at @SussexNeuro @SussexLifeSci in September 2021, to study the modulation of early visual processing by behaviour and neuromodulation.
👉https://t.co/7qitjnxaZN
But there is more...

[FEBS Letters @FEBS_Letters]

👏Highlighted in our new issue: #AmyloidBeta 1-42 internalisation and toxicity are influenced by conformation and assembly state rather than size. Study by @KarenEMarshall @Serpell1 & colleagues →https://t.co/4Mf8FWBydO #neurodegeneration #Alzheimers @Serpelllab @SussexNeuro

[Brain Energy @BrainEnergyLab]

Read @cathnaledi ‘s latest blog all about our #mrc funded research project investigating blood flow and #Alzheimers ! 🧠

[SerpellLab @SerpellLab]

We loved working with you!

[Dr Hannah Franklin @neuroblonde]

This work, during my undergrad @SussexUni in the wonderful @SerpellLab, was what made me pursue a career in research! I contributed a very small amount to this paper but it was a very significant part of my baby science career 🤩 #neuroscience

[SerpellLab @SerpellLab]

Latest work from Devkee Vadukul with ⁦@KarenEMarshall and ⁦@mahmoudbukar⁩ Plus 2 ug project students!! ⁦@neuroblonde⁩ and Astrid!. Internalisation and toxicity of amyloid‐β 1‐42 are influenced by its conformation and assembly state. https://t.co/8aFpbh8yFV

[Alzheimer's Society @alzheimerssoc]

We're excited to announce this year's virtual Carols at Christmas concert (Thursday 17 Dec) will include a performance by musician Paul Harvey!

We would love for you to join us! Book your free ticket today: https://t.co/rR4MQEMFuq (with thanks to @mrnickharvey for the video).

[Wei-Feng Xue @wfxue_lab]

Our latest paper investigating the structural polymorphism of #amyloid fibrils is now published with @SpringerNature in @CommsChem :) we use AFM to reconstruct and quantify amyloid polymorphism: https://t.co/L7qeWf8mGw @LDAubrey @LiisaLutter @CJSerpell @psinomore @SerpellLab

[SerpellLab @SerpellLab]

@AstburyCentre @naranson @RadfordLab @R_U_Gallardo @mattiadanza @George_R_Heath @NatureSMB @Astbury_BSL Beautiful work !

[Henning Stahlberg @LabStahlberg]

PostDoc position in Cryo-EM of Neurodegeneration in our group at the EPFL, Lausanne, Switzerland. We offer excellent working conditions with outstanding equipment in a beautiful city at the Lake of Geneva. More info at https://t.co/i6fQusjfyt

[Wei-Feng Xue @wfxue_lab]

Can we distinguish seeding through templated elongation, where the specific conformation encoded by amyloid fibrils is propagated, from a more generic surface-catalysed seeding mechanism? Yes we can, our new manuscript shows how we did it 😊🔬💡: https://t.co/7Uy6NqNrNp

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