Simon Lauer

[Simon Lauer @SimonMLauer]

Delighted to announce that our piece of research on antimicrobial peptides is now published. A brief tweetorial will follow soon! https://t.co/f6Ufi6VCSb

[Rainer Nikolay @RainerNikolay]

Read our latest #research on antimicrobial peptides that inhibit the activity of the bacterial ribosome in multiple ways, published in @NatureComms Thx to all co-authors & the members of the Grubmüller, Hoffmann and Spahn groups. https://t.co/7mKxsw91h1
https://t.co/dVrZMP6Ej5

[Simon Lauer @SimonMLauer]

@MatthewKraushar 😅🫶🫶

[WilsonLab @WilsonLab2]

Our preprint reporting the structure and mechanism of the natural product translation inhibitors paenilamicins is out…completely novel binding site on the ribosome! https://t.co/wCoi8Safjc…great collaboration with ⁦@Suessmuth_Lab⁩ ⁦@shuramankin⁩

[WilsonLab @WilsonLab2]

Hot of the press...a ribosome story with a twist! We show how the 3' to 5' exonuclease RNase R twists the head of the small 30S subunit by 160° to mediate degradation...https://t.co/qnJxoxOIHo

[Matthew L. Kraushar @MatthewKraushar]

it was a blast teaming up with @SigmaJuly @AndersHLund @therealLundLab on this story about diverging paths of ribosome modification in development 🤩

...from the earliest lineage specifications to neuronal fates!

congrats to the whole team 🥳

[Arnaud Vanden Broeck @AVBroeck]

Pleased to share our latest work where we combined genome editing, biochemistry and cryo-EM to reveal the structural basis for human nucleolar and nuclear pre-60S biogenesis.

https://t.co/sQFcbyDGfR

[Simon Lauer @SimonMLauer]

@BasuShaon @RainerNikolay thanks a lot Shaon :)

[Simon Lauer @SimonMLauer]

Extremely happy that the first work of PhD is now published:
https://t.co/lvYm7OAMrH
Huge thanks to all the co-authors + my supervisors Christian Spahn and @RainerNikolay.
Many thanks to the on-point reviews and to Nature communications for such a nice publishing experience! 🧵

[Simon Lauer @SimonMLauer]

Late assembly steps are potentially assisted by the long tentacle loops of L-proteins that project into the center of the subunit and may sample rRNA segments to lock them in their final position.

[Simon Lauer @SimonMLauer]

While early assembly proceeds domain-wise, formation of domains IV and V progresses in an incremental manner.

[Misha Kudryashev 🔬 ❄🕊️ @MishaKudryashev]

Here we present tomoBEAR - our workflow for processing cryo-ET data for solving structures in situ.

It helps us a lot in our group and we are happy to share it.

Preprint: https://t.co/gZZbF7Hmai
Presented by: Nikita @N1k_t0 Artsemi @Artsemi_Y Vasilii @mikahydrolysis et al

[Mankin_Vazquez_Lab @shuramankin]

Our paper with the Hoffmann lab on the mechanism of action of the antimicrobial peptide Drosocin is in bioRxiv: https://t.co/jmUgVoHeJ8

[Matthew L. Kraushar @MatthewKraushar]

💥first paper from the Kraushar Lab💥
@MPI_MolGen

how proteostasis builds the most evolutionarily advanced brain region - the neocortex

buckle up folks: a thread with history, summary, and perspective

https://t.co/QzbJuvaSCn

[Chloe Burnside (she/her) @ChemBioChlo]

@rRNAte_ & I are excited to share our work where we visualize native assembly intermediates of the small subunit of the mitochondrial ribosome in yeast and human cells https://t.co/GzQGMEzaze