Today we heard from Kimberley on utilising long nanopore reads to sequence ~4,000 human brain clinical research samples, to further understand Alzheimer’s disease and related dementias #nanoporeconf
Been a great day for publications from the team. @mkoretsky1 and the team great job on showing genetic overlap and in some instances a depletion of genetic risk across and within neurodegenerative diseases.
Dramatic improvement for @nanopore DRS using kits RNA004 vs RNA002 @NUBioE1
a) Human poly-A RNA alignment identity: 2019 (RNA002, 86%), 2022 (RNA002, 89.8%), 2023 (RNA004, 95.6%)
b) Human MT poly-A RNA read alignments (2019 vs 2023). Colored lines = base mismatches
@AkesonUCSC
41 novel targets, network insights and potential tox inferences ... #opensource#openscience ... app here https://t.co/AG2Bi2N3oc.
Awesome work from Chelsea X. A. (sensibly twitter averse) to leverage public resource to do this (thx @OpenTargets and other for the APIs)!
New preprint from the team at CARD, nominating novel drug targets for neurodegenerative disease using multi-omic and genetic data.
Hoping this is a starting point for community target discovery specifically focused on ADRD.
https://t.co/grFO1wSgP8
Funding opportunity! GP2 is co-funding two places for @movedisorder Aspen Course. If you are an early career Movement Disorders Fellow who identifies as belonging to an underrepresented group in #PD research, we encourage you to apply. Deadline is 5/1: https://t.co/zBbwOzPTo8
🎉In case you missed it📢
BLAAC-PD is expanding to six sites, allowing the initiative to continue to grow its partnerships with traditionally underrepresented populations and helping to unlock the genetic architecture of #ParkinsonsDisease. https://t.co/QOLCo0f4hv
@ASAP_Research@ucl@UMBC These are great programs and a wonderful way to be a part of GP2, connect with hundreds of PD researchers around the world, and have an impact in globalizing PD research
If you are a doctor or scientist based in Africa, Asia or Latin America interested in getting a master's in clinical neurology or data science via distance learning @ucl or @UMBC, apply for GP2 support! Learn more: https://t.co/HA76fAsqmM