Latest on Alternative Splicing

Retweets of alternative splicing tweets. Fell free to tag @SplicingNews if you want some splicing-related content to be retweeted. Acoount managed by @m1quelag.

[Latest on Alternative Splicing @SplicingNews]

Hey all, this page and @m1quelag joined the bluesky community:

https://t.co/JiKry2m3xd

https://t.co/BHcGGcc8sj

[Deeksha Thakur, PhD @Deeeksha_Thakur]

Is splicing ✂️ making it difficult😵‍💫to keep track of the translated protein from your favorite gene?
Not anymore...
@SplicingNews
#AlternativeSplicing #Genomics #Database #scicomm #AcademicTwitter

[Jose Lucas Lab @JJLucasLab]

Finally out https://t.co/NwSmunseCb the study (led by @xsalvatella1 & @RMendezLab) with the biophysical explanation for the profound effect of the microexon of CPEB4 as cause of autism, that we previously reported back in 2018
@ParrasAlbert @GeschwindLab @mirimiam @hervas_millan

[Molecular Cell @MolecularCell]

Online Now: Nutrient control of growth and metabolism through mTORC1 regulation of mRNA splicing https://t.co/1C5h07Ahbf

[UW Rheumatology @UWRheum]

Jointly presenting research on etiology/pathogenesis: we have Tomas Mustelin, MD, PhD and Rayan Najjar, MD, MPH presenting "Splicing into Action: Investigating the Role of Alternative Splicing in Rheumatoid Arthritis Neutrophils" @ 10:30 AM EST/7:30 AM PST! #ACR24 #UWRheum

[jobRxiv @jobRxiv]

PhD Student: Alternative splicing in auxin pathways @_kamilruzicka

PhD project: characterization of auxin-related splice isoforms in Arabidopsis.

https://t.co/2aKqWDdlcn

#alternative_splicing #auxin #development #plant_genetics #plant_hormones #RNA_s...
https://t.co/2aKqWDdlcn

[Nasrollah Rezaei-Ghaleh @NRezaeiGhaleh]

Interested in a #postdoc position in biomolecular #NMR?
Please check out the following link for a 2-year postdoc position in my group to study RNA splicing by NMR at University of Pavia.
https://t.co/dt0610prQU

[Words & Unwords @wordsandunwords]

All Spliced Up Inside RNA Splicing Tee: https://t.co/XZ13C0ABqt #allsplicedup #inside #RNA #matureRNA #introns #exons #RNAsplicing #funny #geek #humor #biotechology #biotechnologist #molecularbiology #molecularbiologist #biologyteacher #genetics #attitude

[lolly🦋 @lollyHalla]

Assessing the Impact of Novel BRCA1 Exon 11 Variants on Pre-mRNA Splicing https://t.co/hDddJWeKSO #mdpicells via @Cells_MDPI

[Earlham Institute @EarlhamInst]

📣 Fully-funded #PhD with Prof Anthony Hall, this project applies state-of-the-art #sequencing and #computational approaches, in collaboration with leading wheat breeders, to understand how RNA splicing influences the transcriptional landscape of #wheat.

https://t.co/pXz8hcYMt5

[Dr Imran Sheikh 🩺 @DrImranSheikh]

Inhibition of RNA splicing triggers CHMP7 nuclear entry, impacting TDP-43 function and leading to the onset of ALS cellular phenotypes
https://t.co/C6DAghg7sb

[MTBatGSBS @MTBatGSBS]

Congratulations to Rachel Shoemaker, second-year MTB student in Dr. Dung-Fang Lee’s lab, on being awarded a CPRIT-funded BIG-TCR predoctoral fellowship! Rachel’s work is focused on p53-dysregulated alternative splicing in osteosarcoma.

[Nature Reviews Disease Primers @DiseasePrimers]

Besides transcription repression, alternative functions have been described to of #MeCP2 including transcriptional activation, #microRNA processing, #chromatin architecture and alternative splicing https://t.co/VLetZDUdIC

[GeroScience @GeroScienceAGE]

📢New in GeroScience by Springer Nature
Investigating the influence of the SIRT6 gene and alternative splicing on canine longevity: an in-depth bioinformatics analysis and experimental confirmation via NGS-based targeted sequencing by Özge Özmen & Gülin Köklü.
https://t.co/xPAOVx5JGt
#alternativesplicing #dog #canine #longevity #SIRT6 #NGSbasedtargetedsequencing

[Dale Yuzuki @DaleYuzuki]

Pigini #ASHG24 Narrowed further with those vars involved in neurological disorders, 529 pathogenic variants, 345 poison exons. Selected genes for targeted validation (about 14). Uses Prime editing, validating variant effect on poison exon splicing.

[Dale Yuzuki @DaleYuzuki]

Paolo Pigini (Mass Gen Hosp MA) #ASHG24 Defining the landscape of poison exon splicing events in the human brain: implications for neurodevelopmental and neurodegenerative disorders

[Dale Yuzuki @DaleYuzuki]

Sangermano #ASHG24 Shows diagram of exon inclusion events (GFP neg), and exon skipping events with GPF pos pools. HTSA = high throughput skipping assay. For 3' or 5' splicing errors, ref seq and var seq as combined libraries, and do RT-PCR and NGS sequence - to see alt splices

[Dale Yuzuki @DaleYuzuki]

Ramadesikan #ASHG24 Showing Firefly plot of GNAS, a tool they developed in-house. An imprinted locus; enrolled in rare disease program. RNAseq shows intron 5 variant - Shows a sashimi plot with differing splicing patterns. Evidence for exon 5 skipping.

[Earlham Institute @EarlhamInst]

📣 Fully-funded #PhD with @WHaerty exploring characterisation of noise in alternative splicing.

This highly collaborative project will develop skills in experimental and computational biology in a rapidly developing field.
https://t.co/C5OJIFnbPv

[jobRxiv @jobRxiv]

PhD Student: Alternative splicing in auxin pathways @_kamilruzicka

PhD project: characterization of auxin-related splice isoforms in Arabidopsis.

https://t.co/qkV40mIVu2

#alternative_splicing #auxin #development #plant_genetics #plant_hormones #RNA_s...
https://t.co/qkV40mIVu2