Geschwind Lab @ UCLA

Integrative #Genetics, #Genomics, and #Bioinformatics, with basic and clinical #Neuroscience, of neurologic and psychiatric disease.
Tweets from lab members.

[Geschwind Lab @ UCLA @GeschwindLab]

Thanks to Pico Caroni, @AllenInstitute and other organizers/sponsors for a great inaugural conference on the Neurobiology of Mental health. Fantastic program and setting in Thun, Switzerland. @LakeConferences

[Michael Gandal @mikejg84]

New in @ScienceMagazine: Our paper mapping gene/isoform/splicing regulation at pop-scale during human #neurodevelopment.
Major developmental shifts in #genetic reg.,
New colocalized risk genes at ~60% of #psych #GWAS loci. #PsychENCODE24
https://t.co/COilXdAAAh

[Nadav Ahituv @NadavAhituv]

Characterizing >100,000 sequences in primary neurons and organoids and deep learning to decode regulatory activity. Amazing work from @Chengyu_Deng_, @seawhalen, Katie Pollard, @LabNowakowski and others as part of #PsychENCODE in @ScienceMagazine.

https://t.co/Y8oPRkqVVF

[Geschwind Lab @ UCLA @GeschwindLab]

This represents the culmination of years of work by the @NIMHgov #PsychENCODE consortium! furthering our understanding into the genetic and molecular mechanisms of neuropsychiatric conditions🧠🧬 Read more in @ScienceMagazine: https://t.co/cCinMGIRQ2 #Genomics #Neuroscience

[Geschwind Lab @ UCLA @GeschwindLab]

Excited to announce our new pivotal work on autism in the latest #PsychENCODE collection, https://t.co/0YwmHtsxQP
see also @MarkGerstein, @mikejg84 #autism #genomics

[Geschwind Lab @ UCLA @GeschwindLab]

Proud of our UCLA CART colleagues!

[UCLA CART @UCLACART]

A study co-led by researchers at UCLA CART has found distinct brain connectivity patterns in six-week-old infants at risk for developing autism spectrum disorder (ASD). https://t.co/IqI7RHuZ1t

[Geschwind Lab @ UCLA @GeschwindLab]

Our latest publication led by Yonatan Cooper identifying new dementia risk genes using MPRAs to screen noncoding GWAS variants of neurodegenerative disorders w/ functional validation in neurons and microglia @MartinUCSF @srikosuri @giovannicoppoIa
https://t.co/lTEZklEsCA

[Geschwind Lab @ UCLA @GeschwindLab]

Our latest publication from Chris Hartl characterizing brain-wide and brain region-specific gene co-expression, providing a framework to contextualize neuropsychiatric genetic risk, supporting polygenic models of disease
https://t.co/y34R5GYjQ1 @kasper_lage @alexisjbatte

[Geschwind Lab @ UCLA @GeschwindLab]

Dr. Geschwind recently served as a witness in a congressional hearing coordinated by Congresswoman Karen Bass. His testimony focused on introducing Autism Spectrum Disorder. Take a few minutes to listen to Dr. Geschwind's statement: https://t.co/05B7xbAOds.

[Geschwind Lab @ UCLA @GeschwindLab]

@choekatr @katycelina_ @RychlikJoshua Congrats, Katrina!!

[Jordan Smoller @jorsmo]

Announcing the 1st Annual Conference on Precision Psychiatry! Grateful to our amazing speakers @NIMHDirector @AllofUsCEO @WrayNaomi @royperlis @GregSimonKPWHRI @clesemartin @CRodriguezMDPhD @GeschwindLab
@tanzeemc @Stanford_PMHW + more!
RT & Register here:
https://t.co/8dZrg6u0HX

[Aaron Gordon @Aaron_Gordon1]

Our paper looking at the long-term maturation of cortical organoids is out! https://t.co/odhiMtMOCh #organoids #brainorganoids

TL;DR - human cortical organoids start to resemble postnatal cortical development after 250-300 days of culturing

[Geschwind Lab @ UCLA @GeschwindLab]

Dr. Geschwind leads IPH and played a major role in securing this gift. We are very thankful to our donors, Dr. Allen and Charlotte Ginsburg!

Read more: https://t.co/THrI92uDEi

[Geschwind Lab @ UCLA @GeschwindLab]

Thrilled to share that UCLA received a $29M gift to establish a center within the Institute for Precision Health (IPH). which will enable Scientists & physicians to work side by side to examine the role of genetics in disease and develop therapies that improve patients’ lives.

[WashU Medicine Genetics @WashUGenetics]

Don't forget to join us for the Spring 2021 Seminar Series today at noon! Speaker is Daniel Geschwind, MD, PhD, from @UCLA. Here's the Zoom webinar link: https://t.co/jFzBpqmzHP #WashUGen @GeschwindLab

[Finding Genius Podcast @finding_genius]

@UCLAHealth @GeschwindLab Making Sense of Sequencing: Exome Sequencing Analysis and What's Next.

Listen to it here: https://t.co/R4xem2wSW0

Episode also available on @ApplePodcasts: https://t.co/vvIr3KpLhS

#geneexpression #genetics #genomics #sequencing #Findinggeniuspodcast

[Geschwind Lab @ UCLA @GeschwindLab]

@jillhaney21 successfully defended her thesis today - woohoo!

We couldn't be more proud of Jill, and we appreciate all the contributions she made to both @GeschwindLab and @GandalLabUCLA. Congratulations, Dr. Haney!

[Biological Psychiatry @BiologicalPsyc1]

Now out! From @GeschwindLab @UCLA : Abnormal social and repetitive behaviors and elevated striatal dopamine, a molecular hallmark of human psychosis, in a Maternal Immune activation non-human primate model https://t.co/vbfVy19yo8

[Gokul Ramaswami @Gokul_Ramaswami]

Proud and excited to share our work on multi-omic integration in Autism! 1/4

https://t.co/nbSFz3ET06

[Dr. Rebecca Walker @RebLWalker]

My commentary on integrative genomics for the interpretation of genetic loci implicated in neurodevelopmental disorders is out today in @BiologicalPsyc1!! I had a lot of fun writing this and reflecting on all that I’ve learned from the great @GeschwindLab https://t.co/x0xAIew0PO