Dr. Rebecca Walker

Computational Biologist | Former IBD + microbiome Postdoc @TheXavierLab @Broadinstitute | Bioinformatics PhD + neuropsychiatric genomics @GeschwindLab @UCLA

[Toufic Mayassi @TouficMayassi]

1/ Keen to share the story of my postdoc research in @TheXavierLab! We built a massive resource characterizing the spatial landscape of the gut, and yes, we dug deep into the biology too. If you’ve got a minute, let me walk you through the story. 🧵👇

https://t.co/sKL3yyCCKZ

[Dr. Rebecca Walker @RebLWalker]

@tanyaphung Check the psychENCODE portal

[Xavier Lab @TheXavierLab]

Excited to share our latest study uncovering gut microbes and microbial metabolites linked to cardiovascular health! We show that Oscillibacter is associated w/decreased cholesterol in human subjects & that these bacteria take up &metabolize cholesterol.

https://t.co/WOCKfF1xHG

[Laura Kiessling @ChemicalBiology]

Human lectins a part of our innate immune system, they influence the #microbes that live in us. What species do they bind?
@KiesslingGroup
@TheXavierLab
@ejalm
developed Lectin-Seq as a method to mine the human #microbiome. Excited to share the strategy:https://t.co/TJQOapHgyA

[Michael Gandal @mikejg84]

Our latest preprint, profiling gene regulation in >670 developing human brains!

Driven by exceptional PhD student @cindywen2019

"Cross-ancestry, cell-type-informed atlas of gene, isoform, and splicing regulation in the developing human brain." https://t.co/pYJq2nYVa2

[Robert Lyle McPherson @LyleMcPherson1]

Excited to share a pre-print of our work in the @KiesslingGroup describing interactions between human lectins and stool microbiota. Some highlights below: (1/4)

https://t.co/S97CWIu4FC

[Eric Brown @ericmichbrown]

Ever wondered how oral microbes colonize the gut? Turns out gut inflammation opens up a niche Veillonella can exploit through nitrate utilization. Congrats to @DanielRojas150 and the team for all the help @emilytemple_ @monyekaba1 @Ahmedbiooo @RebLWalker https://t.co/zgUeELhCQQ

[Dr. Rebecca Walker @RebLWalker]

Congrats @DanielRojas150 @ericmichbrown !! Happy to be a (small) part of this work

[Xavier Lab @TheXavierLab]

Check out our study in @NatureMicrobiol describing how oral microbe #Veillonella parvula switches its metabolism to utilize inflammatory nitrate & colonize the gut.

https://t.co/lbZ3KXrW7I

[Dr. Rebecca Walker @RebLWalker]

Congrats Thomas!

[Thomas Pedersen @thomaskainamura]

Among billions of potential microbiome epitopes hide few immunodominant 'keystone' epitopes recognized by T cells. Out today in @ImmunityCP, we discover keystone epitopes and show T cell responses to reflect intestinal immune health. https://t.co/YE9zHrd3y9

[Dr. Rebecca Walker @RebLWalker]

Check out my latest work exploring the gut microbiome of the Framingham Heart Study participants

[Xavier Lab @TheXavierLab]

Out now in @GenomeMedicine! Read about our latest efforts, led by @RebLWalker, exploring associations between diet, lifestyle, & cardiometabolic disease phenotypes w/the gut #microbiome among the @FraminghamStudy participants.
https://t.co/UP2tXYNOc1

[Eric Brown @ericmichbrown]

Super excited to be able to share this study on gut microbiome ADP-ribosyltransferases and their role as phage-encoded fitness factors in the gut. Been a great collaboration with @HASCiencia and @Novartis along with @broadinstitute @MGH_RI & @emilytemple_ https://t.co/HreT2e3ddx

[Nature Neuroscience @NatureNeuro]

Examination of gene co-expression network architecture in human brain samples from @GTExPortal ; new from @GeschwindLab and colleagues

https://t.co/EUm2lj0LWj

[Xavier Lab @TheXavierLab]

Multi-omic profiling in IBD patients initiating biologic therapy identifies remission-associated gut microbial features. Our findings provide a foundation for more individualized selection of optimal therapeutic agents. Online now @cellhostmicrobe:
https://t.co/7qWyk3PL1y

[Chirag Krishna @chirag_msk]

A comprehensive, integrated review of unconventional T cells- excellent stuff from @TouficMayassi- https://t.co/8pSlS2ddhU

[Xavier Lab @TheXavierLab]

We are excited to share work by @johannesfscheid, @cobarnes27, and @basak_ersln with @bjorkmanlab, Regev lab, and @PaulBieniasz lab characterizing B cell responses against #SARSCoV2. (1/3) @broadinstitute
Online @CellCellPress: https://t.co/KrJlwSLIdz

[Dr. Rebecca Walker @RebLWalker]

@chirag_msk @cancercell @GeneCollector @MingLiLab @arihakimi Congrats!!

[Roderic Guigó @RodericGuigo]

Seen at netflix’s “The one”

[Xavier Lab @TheXavierLab]

In a collaboration with the Weersma lab out now in
@NatureComms, we show that intestinal mucosa cis-eQTLs in IBD can depend on inflammatory status and be influenced by the cell type composition of the mucosa.

Read about this work:
https://t.co/fsXcuzi8Ux

[Dr. Rebecca Walker @RebLWalker]

@goGUrtecho @HHMINEWS @harriswangnyc @srikosuri @GeiselBiofilm Congrats Guillaume!!

[Dr. Rebecca Walker @RebLWalker]

@kellyanneduncan @ShipraVaishnava Congrats!!