New paper: we show a role for our favorite transcription factor Osr1 in our favorite #stromal cells to non cell autonomously regulate #lymphangiogenesis
Out now in @Dev_journal
https://t.co/Y03ezfd61y
Happy to share the latest paper from our lab: https://t.co/zaqknrXYes where we propose that multipotent progenitors from the dorsal aortic compartment in E9.5 mouse embryos contribute to the formation of brown adipose tissue depots
Hey Muscle And Metabolism Folks on Twitter, @LykkeSylow and I are looking for a Postdoc who is interested in applying for a prestigious @DDEA_Denmark fellowship with us. More details in the picture attached. Please share widely! @MYOTWlTTER
Myc and muscle growth: necessary in muscle stem cells, dispensable in muscle fibers and harmful if overexpressed. Check out our latest work https://t.co/ACbr55RXuz in @NatureComms, where we explore the role of Myc in muscle growth and more.
Mesenchymal Osr1+ cells regulate embryonic lymphatic vessel formation
Read this Research Article by Pedro Vallecillo-García, Sigmar Stricker @StrickerLab (@FU_Berlin@ChariteBerlin) and colleagues:
https://t.co/5rfxA12lk0
Loss of Osr1 leads to altered matrix deposition impairing proliferation of lymph endothelial cells (LECs) at the sprouting tip, while decreased expression of signaling factors as Cxcl12 impairs LEC migration.
New paper: we show a role for our favorite transcription factor Osr1 in our favorite #stromal cells to non cell autonomously regulate #lymphangiogenesis
Out now in @Dev_journal
https://t.co/Y03ezfd61y
So...Mammals normally store fat under the skin in an even layer, but camels evolved to pile fat in one spot, so the rest of their bodies can stay cool in the desert.
Why don't other desert animals do this?
Well, they do.... but for some reason, we never talk about them..... 🧵🧵
Hey #myotwitter! Enjoy this week’s papers on the regulation of skeletal muscle. It features metabolism, sarcopenia, dystrophy, development, exercise, and more.
👇
https://t.co/69ujeHL4Bi
Highlighting work from
@ValFajardoPhD@SamMathew_RCB@StrickerLab
Thanks
@Bims_BiomedNews
New preprint from @LeGrandLab1@GarciaPaulineJ : Setdb1 safeguards genome integrity in muscle stem cells to allow for regenerative myogenesis and inflammation https://t.co/bwRR9yClqe
While studies as these are only a very small step towards providing treatment to patients suffering from complex diseases as NF1, we hope this contributes to the understanding of an important phenotypic facet of NF1 @nfnetwork@NFibromatosis@neurofibroma_uk@ChildrensTumor
This was coupled to premature muscle stem cell quiescence induction via Notch pathway activation; blunting Notch signaling during early postnatal development ameliorated the muscle phenotype in this model.
New on BioRxiv: Adhesion energy controls lipid-binding mediated endocytosis. A group effort lead by @RaluucaG with contributions from our friends @taraskalab @DimovaLab @cmatthaeus2 and Thomas Weikl @MpiciPotsdam@FUBiochemistry@FU_Berlin https://t.co/TqkThLdKqW