Scientific Project Manager at DKMS Germany. Working on immune biology and stem cell transplantation.
Interested in kite surfing and Brasilian jiu-jitsu
Cancer Cachexia: Liver Identified as Active Driver of Body Wasting
👉 https://t.co/DY1PTMaiRp
Up to half of all #cancer patients experience #cachexia – a severe syndrome marked by dramatic loss of muscle, fat, and even heart tissue. It is a major cause of therapy resistance, complications, and increased mortality.
🔬A new study led by researchers at #HelmholtzMunich, in collaboration with University Hospital Heidelberg, the @TU_Muenchen, and the @DiabResearch, identifies the #liver as a key contributor to this condition.
🕒The team discovered that a key liver clock gene, REV-ERBα, is silenced during cachexia, leading to the release of harmful hepatokines. These molecules trigger tissue-wasting processes in fat and muscle cells. Reactivating REV-ERBα in preclinical models reduced body wasting significantly.
💡The findings provide a comprehensive molecular dataset and may open new avenues for diagnosis and therapeutic development.
💬“For the first time, we were able to show that the liver is not merely a passive responder to cachexia, but actively contributes to the progression of the disease. Our findings open up new possibilities to better diagnose the syndrome and explore therapeutic interventions.”
– Dr. Mauricio Berriel Diaz
💬“These results clearly demonstrate the importance of systemic organ interactions in the progression of cancer.”
– Prof. Stephan Herzig
@Dorie00@FiskerSchmidt@BerrielDiaz
#CancerResearch #LiverFunction #BiomedicalResearch
#WomenAtHelmholtzMunich
👏 #HelmholtzMunich is celebrating inspiring careers and female leadership, because #ScienceNeedsHer!
👉 Check out our website and learn more about #WomenInScience at Helmholtz Munich: https://t.co/COozFBWkB1
🌟 Get inspired by thoughts of some of our top female scientists!
🎙️ What advice would you give your younger self?
🗨️ “Surround yourself with inspiring people, delegate efficiently and learn how to say no.”
- Prof. Eleftheria Zeggini, Director of the Institute of Translational Genomics
🎙️What would you change for future generations?
🗨️"I would create a future where origin, race, and background are not even thought of in the workplace. Instead, everyone would be valued and united in the scientific endeavor based solely on their commitment, passion, work quality, and ethics."
- Prof. Maria-Elena Torres-Padilla, Director of the Institute for Epigenetics and Stem Cells
🎙️What advice would you give your younger self?
🗨️“Be yourself, follow your passion, be curious and ask bold questions. Trust the journey, foster team growth and diverse perspectives. Science is a marathon, not a sprint - enjoy growing along the way.”
- Prof. Carolin Daniel, Head of the Research Unit “Type 1 Diabetes Immunology”
🎙️What was your career booster?
🗨️“Not doing it alone - a supportive network of colleagues, mentors, friends, and family, as well as taking turns not only in private, but also professionally and collaboratively. While there has certainly been an element of chance, seeking and then also daring to seize opportunities has been invaluable.”
- Prof. Julia Schnabel, Director of the Institute of Machine Learning in Biomedical Imaging
@helmholtz_en@ja_schnabel@EleZeggini@METorresPadilla
#WomenInSTEM #GenderEquality #InspiringWomen #WomenInspiringWomen #CelebrateWomen
Türen auf mit der Maus bei #HelmholtzMunich!
🔬Rund 50 Kinder wurden heute zu Forschenden bei #HelmholtzMunich:
👉 https://t.co/gVsVPe4jR7
👩🔬🧑🔬Unsere Experten öffneten ihre Labore und zeigten, wie #Gesundheitsforschung funktioniert.
🧬DNA extrahieren, Betazellen unter dem Mikroskop bestaunen… und was hat es eigentlich mit der Abnehmspritze auf sich?
Dieses und vieles mehr begeisterte Kinder und Eltern!
Die Aktion „Türen auf mit der Maus“ wird jährlich vom @WDR veranstaltet.
🤝Das Motto: „#ZusammenTun“!
#TürenAuf #TürenAufMitDerMaus #HelmholtzMunich #ZusammenTun #WDR #Abnehmspritze #Diabetes #Prävention #Früherkennung
Happy #WorldMarrowDonorDay! Ein großes Danke an alle Spender:innen!💗 Eure Hilfsbereitschaft gibt Patient:innen auf der ganzen Welt Hoffnung. Und für alle, die sich noch nicht registriert haben, ist der heutige #WMDD die perfekte Gelegenheit dazu!💪 #CheersToTenYears#WMDD24
PLEASE RT/SHARE
Readvertising for a Postdoc RA/Fellow to work on a 12M project focusing on FGF21 and alcohol intake/preference.
Do get in touch if interested.
https://t.co/WyKG6KStBA
Call for applications: DKMS John Hansen Research #Grant 🎓
Are you a young scientist passionate about advancing blood cancer therapy? DKMS supports outstanding #research projects in the field of stem cell transplantation or cell therapy.
Apply now!✏️
https://t.co/A3PJgGhUn8
Sex-specific selection on reproductive fitness contributes to the maintenance of variation at a large effect locus in Atlantic salmon.
And - we got the cover photo too! 😉👍
@kenyon_mobley @FishConGen @helsinkiuni@UiTNorgesarktis@LukeFinland
https://t.co/ReoB3gQWX8
Congrats to my colleagues on their work about "Optimisation of global stem cell donor recruitment basedon analysis of unsuccessful donor searches"
https://t.co/bM0TPp48EM
#hsct#DKMS#HLA
Stammzelltransplantation heilt HIV-Patienten https://t.co/0ayru6up4H Durch eine Stammzelltransplantation ist in Berlin erneut ein HIV-Patient geheilt worden – das Aids-Virus ist in seinen Zellen nicht mehr vorhanden. #HIVirus#Stammzellen#Heilung